Journal ArticleDOI
Release characteristics of diclofenac sodium from poly(vinyl alcohol)/sodium alginate and poly(vinyl alcohol)-grafted-poly(acrylamide)/sodium alginate blend beads.
Oya Şanlı,Nuran Ay,Nuran Işıklan +2 more
TLDR
It was observed that, DS release from the beads decreased with increasing PVA/NaAlg (m/m) ratio, drug/polymer ratio (d/p) and extent of cross-linking, but release increased with increasing acrylamide content of the PVA-g-PAAm polymer.About:
This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2007-02-01. It has received 150 citations till now. The article focuses on the topics: Controlled release & Polyvinyl alcohol.read more
Citations
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Journal ArticleDOI
Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres
Avik Kumar Saha,Sarbani Dey Ray +1 more
TL;DR: In this article, an oral sustained release delivery system of sodium diclofenac(DS) based on SA as a hydrophilic carrier in combination with chitosan (CH) and sodium carboxymethyl cellulose (SCMC) as drug release modifiers to overcome the drug-related adverse effects and to improve bioavailability.
Journal ArticleDOI
Fabrication and evaluation of bi-layer tablet containing conventional paracetamol and modified release diclofenac sodium
TL;DR: The results of analysis of variance showed that the friability of paracetamol was distinctly influenced by the formulation variables.
Journal ArticleDOI
Modified tamarind kernel polysaccharide: A novel matrix for control release of aspirin
Sandipta Ghosh,Sagar Pal +1 more
TL;DR: The release characteristics from the matrices under study show non-Fickian diffusion mechanism, suggesting the controlled release of aspirin, and TKP-g-PAM based hydrogels show significant enhancement for control release.
Journal Article
Development of diclofenac sodium-loaded alginate-PVP K 30 microbeads using central composite design
TL;DR: Microbeads for oral controlled delivery of diclofenac sodium were successfully developed by ionotropic gelation to eliminate the need for multiple dosing and adverse effects.
Journal ArticleDOI
Interpenetrating polymer network microspheres of hydroxy propyl methyl cellulose/poly (vinyl alcohol) for control release of ciprofloxacin hydrochloride
B. Yerriswamy,C. Venkata Prasad,C. L. N. Reedy,B. Mallikarjuna,K. Chowdoji Rao,M. C. S. Subha +5 more
TL;DR: In this article, Ciprofloxacin hydrochloride (CFHcl) was loaded into interpenetrating polymer network (IPN) microspheres that are crosslinked with glutaraldehyde (GA).
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Journal ArticleDOI
A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.
Alan Ward,Stephen P. Clissold +1 more
TL;DR: Pentoxifylline offers a well-tolerated and effective alternative to the treatment options available for patients with peripheral vascular disease and in isolated studies proved to be superior to drugs such as co-dergocrine mesylate, adenosine and pyrithioxine.