Journal ArticleDOI
Release characteristics of diclofenac sodium from poly(vinyl alcohol)/sodium alginate and poly(vinyl alcohol)-grafted-poly(acrylamide)/sodium alginate blend beads.
Oya Şanlı,Nuran Ay,Nuran Işıklan +2 more
TLDR
It was observed that, DS release from the beads decreased with increasing PVA/NaAlg (m/m) ratio, drug/polymer ratio (d/p) and extent of cross-linking, but release increased with increasing acrylamide content of the PVA-g-PAAm polymer.About:
This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2007-02-01. It has received 150 citations till now. The article focuses on the topics: Controlled release & Polyvinyl alcohol.read more
Citations
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Journal ArticleDOI
γ-Rays and ion beam irradiation effects on the optical and structural properties of poly (vinyl alcohol)-ethylene glycol composite
TL;DR: In this article, the optical and structural properties of the irradiated PVA-EG composites have been investigated using UV-Vis, FTIR and XRD analytical techniques, showing that the optical band gap energy changes with the type of irradiation and exposure time.
Journal ArticleDOI
Flurbiprofen-loaded interpenetrating polymer network beads based on alginate, polyvinyl alcohol and methylcellulose: design, characterization and in-vitro evaluation.
TL;DR: It was observed that the release of FBP from beads was influenced by variables such as NaAlg amount in polymer matrix, crosslinking time and FBP/polymer ratio, and release mechanism ofFBP from IPN beads followed non-Fickian transport.
Journal ArticleDOI
Preparation of ferric ion crosslinked acrylamide grafted poly (vinyl alcohol)/sodium alginate microspheres and application in controlled release of anticancer drug 5-fluorouracil.
Oya Şanlı,Merve Olukman +1 more
TL;DR: Ionically crosslinked microspheres of acrylamide (AAm) grafted poly (vinyl alcohol) (PVA)/sodium alginate (NaAlg) were prepared by crosslinking with FeCl3 and 5-fluorouracil, which is an anticancer drug and was successfully encapsulated into the micro Spheres.
Novel interpenetrating polymer network mucoadhesive microspheres of gum ghatti and poly(vinyl alcohol) for the delivery of ranitidine hcl
Neelam Jain,Arunabha Banik +1 more
TL;DR: In this article, a novel interpenetrating polymer network (IPN) of gum ghatti (Gg) and poly vinyl alcohol (PVA) was prepared and crosslinked with glutaraldehyde (GA) to form mucoadhesive microspheres by emulsion cross-linking method to deliver model anti-ulcer drug, ranitidine HCl.
Journal ArticleDOI
Synthesis and In Vitro/Ex Vivo Characterizations of Ceftriaxone-Loaded Sodium Alginate/poly(vinyl alcohol) Clay Reinforced Nanocomposites: Possible Applications in Wound Healing
Shabana Bibi,Sadullah Mir,Wajid Rehman,Farid Menaa,Alia Gul,Fatima S. Alaryani,Ali Alqahtani,Sirajul Haq,Magda H. Abdellatif +8 more
TL;DR: In this paper , the in vitro properties of the antibiotic ceftriaxone sodium (CTX) once encapsulated into sodium alginate (SA)/poly(vinyl alcohol)PVA-clay reinforced nanocomposite films were investigated.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Journal ArticleDOI
A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.
Alan Ward,Stephen P. Clissold +1 more
TL;DR: Pentoxifylline offers a well-tolerated and effective alternative to the treatment options available for patients with peripheral vascular disease and in isolated studies proved to be superior to drugs such as co-dergocrine mesylate, adenosine and pyrithioxine.