Journal ArticleDOI
Release characteristics of diclofenac sodium from poly(vinyl alcohol)/sodium alginate and poly(vinyl alcohol)-grafted-poly(acrylamide)/sodium alginate blend beads.
Oya Şanlı,Nuran Ay,Nuran Işıklan +2 more
TLDR
It was observed that, DS release from the beads decreased with increasing PVA/NaAlg (m/m) ratio, drug/polymer ratio (d/p) and extent of cross-linking, but release increased with increasing acrylamide content of the PVA-g-PAAm polymer.About:
This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2007-02-01. It has received 150 citations till now. The article focuses on the topics: Controlled release & Polyvinyl alcohol.read more
Citations
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Journal ArticleDOI
Physical and mechanical properties of sunflower oil and synthetic polymers based bigels for the delivery of nitroimidazole antibiotic – A therapeutic approach for controlled drug delivery
B. Behera,Vinay Singh,Senthilguru Kulanthaivel,Mrinal Bhattacharya,K. Paramanik,Indranil Banerjee,Kunal Pal +6 more
TL;DR: The drug loaded bigels showed equivalent inhibitory zones against Escherichia coli as compared to commercially available formulations and showed a high cell proliferation index and viscoelastic in nature with pseudoplastic flow behavior.
Journal ArticleDOI
Thermoresponsive N-vinyl caprolactam grafted sodium alginate hydrogel beads for the controlled release of an anticancer drug
TL;DR: In this article, a series of graft copolymer beads were synthesized using azobisisobutyronitrile as an initiator, and characterized by Fourier infrared spectroscopy, differential scanning calrimetry and X-ray diffraction for analysis of the amorphous nature drug in the beads.
Journal ArticleDOI
Smart polymeric nanofibers for topical delivery of levothyroxine
Anahita Fathi Azarbayjani,Jayarama Reddy Venugopal,Seeram Ramakrishna,Fung Chye Lim,Yew Weng Chan,Sui Yung Chan +5 more
TL;DR: Polymeric nanofibers were able to sustain the penetration of T₄ to the skin and help maintain the effective drug concentration in the skin layers for longer period of time and may result in great improvement in consumer compliance, avoid frequent dosing and enhance the therapeutic effectiveness.
Journal ArticleDOI
Controlled release study of carbaryl insecticide from calcium alginate and nickel alginate hydrogel beads
TL;DR: Bead characteristics, such as carbaryl entrapment efficiency, particle size, equilibrium swelling degree, and carbaryl release kinetics, were determined and release results indicated that carb Daryl release from both of the Ca-AlG and Ni-Alg beads decreases with the increasing crosslinker concentration, Carb/NaAlg ratio and percentage of NaAlg.
Journal ArticleDOI
Dielectric, thermal, and swelling properties of calcium ion-crosslinked sodium alginate film
TL;DR: In this article, Ca 21 -crosslinked sodium alginate (SA) gel films (SA-Ca/SA2-Ca) have been prepared, and their structural and thermal characterizations were investigated using fourier transform infrared spectroscopy, Xray diffraction, differential scanning calorimetry, and thermogravimetric analysis, respectively.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Journal ArticleDOI
A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.
Alan Ward,Stephen P. Clissold +1 more
TL;DR: Pentoxifylline offers a well-tolerated and effective alternative to the treatment options available for patients with peripheral vascular disease and in isolated studies proved to be superior to drugs such as co-dergocrine mesylate, adenosine and pyrithioxine.