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Renal protective effects of thymoquinone against sodium nitrite-induced chronic toxicity in rats: Impact on inflammation and apoptosis

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TLDR
Treatment with sodium nitrite significantly increased markers of renal dysfunction, oxidative stress, inflammation and apoptosis, and these effects were markedly attenuated by TQ in dose dependent manner.
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This article is published in Life Sciences.The article was published on 2017-07-01. It has received 40 citations till now. The article focuses on the topics: Thymoquinone & Nephrotoxicity.

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The Neuroprotective Effects of Thymoquinone: A Review:

TL;DR: It is purposed that although experimental studies indicated the beneficial effects of TQ against nervous system problems, better designed clinical trials in humans are needed to confirm these effects.
Journal ArticleDOI

Diclofenac-induced renal toxicity in female Wistar albino rats is protected by the pre-treatment of aqueous leaves extract of Madhuca longifolia through suppression of inflammation, oxidative stress and cytokine formation.

TL;DR: Aqueous leaf extract of Madhuca longifolia was observed to show a better result in normalizing the toxicity caused by diclofenac, due to its ability in restoring renal function by restoring antioxidants and preventing cellular damages.
Journal ArticleDOI

Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates α-synuclein aggregation in vitro

TL;DR: Thymoquinone is thought to protect against MPTP-induced PD and the observed neuroprotective effects are attributed to its potent antioxidant and anti-inflammatory properties.
References
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Journal ArticleDOI

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
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Theory and Practice of Histological Techniques

TL;DR: Light Microscopy, Enzyme Histochemistry, and Immunocytochemical Techniques: Diagnostic Cytopathology, Specimen Collection and Preparation.
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Histological and Histochemical Methods: Theory and Practice

TL;DR: This text presents the chemical and physical principles of fixation, staining and histochemistry, and offers a practical guide to the preparation of specimens for light microscopy and includes detailed practical instructions of the techniques used.
Journal ArticleDOI

Old, new and emerging functions of caspases.

TL;DR: Caspase-2 has emerged as a unique caspase with potential roles in maintaining genomic stability, metabolism, autophagy and aging, and some of these less studied and emerging functions of mammalian caspases are focused on.
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