Journal ArticleDOI
Report on a WHO consultation on immunological endpoints for evaluation of new Japanese encephalitis vaccines, WHO, Geneva, 2-3 September, 2004.
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The consultation made a series of recommendations for specifications on immunological criteria to assess JE vaccine efficacy, and more detailed recommendations will be drafted following further consultations to serve as WHO guidelines for evaluation and licensure for new JE vaccines.About:
This article is published in Vaccine.The article was published on 2005-11-01. It has received 203 citations till now. The article focuses on the topics: Vaccine efficacy & Japanese encephalitis vaccine.read more
Citations
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Correlates of Protection Induced by Vaccination
TL;DR: This paper attempts to summarize current knowledge about immune responses to vaccines that correlate with protection, finding some vaccines have no true correlates, but only useful surrogates, for an unknown protective response.
Journal ArticleDOI
Vaccine protection against Zika virus from Brazil
Rafael A. Larocca,Peter Abbink,Jean Pierre Schatzmann Peron,Paolo Marinho de Andrade Zanotto,M. Justin Iampietro,Alexander Badamchi-Zadeh,Michael R. Boyd,David Ng’ang’a,Marinela Kirilova,Ramya Nityanandam,Noe B. Mercado,Zhenfeng Li,Edward T. Moseley,Christine A. Bricault,Erica N. Borducchi,Patricia B. Giglio,David Jetton,George H. Neubauer,Joseph P. Nkolola,Lori F. Maxfield,Rafael De La Barrera,Richard G. Jarman,Kenneth H. Eckels,Nelson L. Michael,Stephen J. Thomas,Dan H. Barouch,Dan H. Barouch +26 more
TL;DR: It is demonstrated that protection against ZIKV challenge can be achieved by single-shot subunit and inactivated virus vaccines in mice and that Env-specific antibody titers represent key immunologic correlates of protection.
Journal ArticleDOI
Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys
Peter Abbink,Rafael A. Larocca,Rafael De La Barrera,Christine A. Bricault,Edward T. Moseley,Michael R. Boyd,Marinela Kirilova,Zhenfeng Li,David Ng’ang’a,Ovini Nanayakkara,Ramya Nityanandam,Noe B. Mercado,Erica N. Borducchi,Arshi Agarwal,Amanda L. Brinkman,Crystal Cabral,Abishek Chandrashekar,Patricia B. Giglio,David Jetton,Jessica Jimenez,Benjamin C. Lee,Shanell Mojta,Katherine Molloy,Mayuri Shetty,George H. Neubauer,Kathryn E. Stephenson,Jean Pierre Schatzmann Peron,Paolo Marinho de Andrade Zanotto,Johnathan Misamore,Brad Finneyfrock,Mark G. Lewis,Galit Alter,Kayvon Modjarrad,Richard G. Jarman,Kenneth H. Eckels,Nelson L. Michael,Stephen J. Thomas,Dan H. Barouch,Dan H. Barouch +38 more
TL;DR: It is demonstrated that three different vaccine platforms protect against ZIKV challenge in rhesus monkeys, and these data support the rapid clinical development of ZikV vaccines for humans.
Journal ArticleDOI
Yellow fever vaccine
TL;DR: The genus Flavivirus is a member of the family Flaviviridae, a group of small, enveloped, positive-sense, single-strand RNA viruses as mentioned in this paper.
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From research to phase III: Preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine
TL;DR: The different steps and challenges of developing CYD TDV are discussed, from research to industrialization, and some of the challenges to the successful introduction of a dengue vaccine into immunization programs are summarized.
References
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Journal ArticleDOI
Role of CD8+ T cells in control of West Nile virus infection.
TL;DR: These experiments suggest that, while specific antibody is responsible for terminating viremia, CD8+ T cells have an important function in clearing infection from tissues and preventing viral persistence.
Journal ArticleDOI
Protection against Japanese Encephalitis by Inactivated Vaccines
Charles H. Hoke,A Nisalak,N Sangawhipa,S Jatanasen,T Laorakapongse,Bruce L. Innis,S Kotchasenee,John B. Gingrich,J R Latendresse,K Fukai +9 more
TL;DR: It is concluded that two doses of inactivated Japanese encephalitis vaccine, either monovalent or bivalent, protect against encephalitis due to JapaneseEncephalitis virus and may have a limited beneficial effect on the severity of dengue hemorrhagic fever.
Journal ArticleDOI
Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants.
Luis Jódar,Jay C. Butler,George M. Carlone,Ron Dagan,David Goldblatt,Helena Käyhty,Keith P. Klugman,Brian D. Plikaytis,George R. Siber,Robert Kohberger,Ih Chang,Thomas Cherian +11 more
TL;DR: This report analyses the various options with their relative merits and drawbacks and provides preliminary recommendations as guidance to regulatory agencies in evaluating these vaccines for the purposes of licensure.
Journal ArticleDOI
Effectiveness of live-attenuated Japanese encephalitis vaccine (SA14-14-2): a case-control study.
Sean Hennessy,Brian L. Strom,Warren B. Bilker,L. Zhengle,W. Chao-Min,L. Hui-Lian,W. Tai-Xiang,Y. Hong-Ji,L. Qi-Mau,Theodore F. Tsai,N. Karabatsos,Scott B. Halstead +11 more
TL;DR: It is concluded that a regimen of two doses of live-attenuated Japanese encephalitis vaccine, administered 1 year apart, is effective in the prevention of clinically important disease.
Journal ArticleDOI
Chimeric live, attenuated vaccine against Japanese encephalitis (ChimeriVax-JE): phase 2 clinical trials for safety and immunogenicity, effect of vaccine dose and schedule, and memory response to challenge with inactivated Japanese encephalitis antigen.
Thomas P. Monath,Farshad Guirakhoo,Richard A. Nichols,Sutee Yoksan,Robert Schrader,Christopher J. Murphy,Paul S. Blum,Stephen Woodward,Karen McCarthy,Danell Mathis,Casey Johnson,Philip Bedford +11 more
TL;DR: ChimeriVax-JE appears to be a safe vaccine that provides protective levels of neutralizing antibody after a single dose.