Resting state fMRI: A review on methods in resting state connectivity analysis and resting state networks.
K A Smitha,K Akhil Raja,K M Arun,P.G. Rajesh,Bejoy Thomas,T R Kapilamoorthy,Chandrasekharan Kesavadas +6 more
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TLDR
The concept of resting state functional magnetic resonance imaging is introduced in detail, three most widely used methods for analysis are discussed, and a few of the resting state networks featuring the brain regions, associated cognitive functions and clinical applications are described.Abstract:
The inquisitiveness about what happens in the brain has been there since the beginning of humankind. Functional magnetic resonance imaging is a prominent tool which helps in the non-invasive examination, localisation as well as lateralisation of brain functions such as language, memory, etc. In recent years, there is an apparent shift in the focus of neuroscience research to studies dealing with a brain at 'resting state'. Here the spotlight is on the intrinsic activity within the brain, in the absence of any sensory or cognitive stimulus. The analyses of functional brain connectivity in the state of rest have revealed different resting state networks, which depict specific functions and varied spatial topology. However, different statistical methods have been introduced to study resting state functional magnetic resonance imaging connectivity, yet producing consistent results. In this article, we introduce the concept of resting state functional magnetic resonance imaging in detail, then discuss three most widely used methods for analysis, describe a few of the resting state networks featuring the brain regions, associated cognitive functions and clinical applications of resting state functional magnetic resonance imaging. This review aims to highlight the utility and importance of studying resting state functional magnetic resonance imaging connectivity, underlining its complementary nature to the task-based functional magnetic resonance imaging.read more
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Resting state connectivity differences in eyes open versus eyes closed conditions
Oktay Agcaoglu,Tony W. Wilson,Yu-Ping Wang,Julia M. Stephen,Vince D. Calhoun,Vince D. Calhoun +5 more
TL;DR: The results indicated that resting‐state condition is an important variable that may limit the generalizability of clinical findings using rs‐fMRI, and that task condition significantly affected a wide range of networks.
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Simultaneous resting-state FDG-PET/fMRI in Alzheimer Disease: Relationship between glucose metabolism and intrinsic activity.
Rocco Marchitelli,Marco Aiello,Arnaud Cachia,Mario Quarantelli,Carlo Cavaliere,Alfredo Postiglione,Gioacchino Tedeschi,Patrizia Montella,Graziella Milan,Marco Salvatore,Elena Salvatore,Jean-Claude Baron,Sabina Pappatà +12 more
TL;DR: Results support the presence of bioenergetic coupling between glucose utilization and rapid transmission of neural information in healthy ageing, which is substantially reduced in aMCI/AD, suggesting that abnormal glucose utilization is in some way linked to communication breakdown among brain regions impacted by the underlying pathological process.
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Resting State Dynamic Functional Connectivity in Neurodegenerative Conditions: A Review of Magnetic Resonance Imaging Findings.
TL;DR: This review summarizes the main currently available approaches for dFC analysis and reports their recent applications for the assessment of the most common neurodegenerative conditions, including Alzheimer's disease, Parkinson’s disease, dementia with Lewy bodies, and frontotemporal dementia.
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Functional Connectivity Signatures of Parkinson's Disease.
TL;DR: The present narrative review attempts to summarize the most recent RS-fMRI findings highlighting the role of brain networks re-organization and adaptation in the course of PD.
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A review of resting-state fMRI and its use to examine psychiatric disorders
TL;DR: In this review, rs-fMRI and its advantages over task based fMRI, its currently used analysis methods, and its application in psychiatric disorders using different analysis methods are discussed.
References
More filters
Journal ArticleDOI
Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
Journal ArticleDOI
An information-maximization approach to blind separation and blind deconvolution
TL;DR: It is suggested that information maximization provides a unifying framework for problems in "blind" signal processing and dependencies of information transfer on time delays are derived.
Journal ArticleDOI
Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
Journal ArticleDOI
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Michael D. Fox,Abraham Z. Snyder,Justin L. Vincent,Maurizio Corbetta,David C. Van Essen,Marcus E. Raichle +5 more
TL;DR: It is suggested that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain, featuring the presence of anticorrelated networks in the absence of overt task performance.
Journal ArticleDOI
Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control
William W. Seeley,Vinod Menon,Alan F. Schatzberg,Jennifer Keller,Gary H. Glover,Heather A. Kenna,Allan L. Reiss,Michael D. Greicius +7 more
TL;DR: Two distinct networks typically coactivated during functional MRI tasks are identified, anchored by dorsal anterior cingulate and orbital frontoinsular cortices with robust connectivity to subcortical and limbic structures, and an “executive-control network” that links dorsolateral frontal and parietal neocortices.
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