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Open AccessJournal ArticleDOI

Right Ventricular Function in Cardiovascular Disease, Part I Anatomy, Physiology, Aging, and Functional Assessment of the Right Ventricle

Francois Haddad, +3 more
- 18 Mar 2008 - 
- Vol. 117, Iss: 11, pp 1436-1448
TLDR
The goal of the present review is to offer a clinical perspective on RV structure and function, using echocardiography and magnetic resonance imaging to create new opportunities for the study of RV anatomy and physiology.
Abstract
In 1616, Sir William Harvey was the first to describe the importance of right ventricular (RV) function in his seminal treatise, De Motu Cordis : “Thus the right ventricle may be said to be made for the sake of transmitting blood through the lungs, not for nourishing them.”1,2 For many years that followed, emphasis in cardiology was placed on left ventricular (LV) physiology, overshadowing the study of the RV. In the first half of the 20th century, the study of RV function was limited to a small group of investigators who were intrigued by the hypothesis that human circulation could function adequately without RV contractile function.3 Their studies, however, were based on an open pericardial dog model, which failed to take into account the complex nature of ventricular interaction. In the early 1950s through the 1970s, cardiac surgeons recognized the importance of right-sided function as they evaluated procedures to palliate right-heart hypoplasia. Since then, the importance of RV function has been recognized in heart failure, RV myocardial infarction, congenital heart disease and pulmonary hypertension. More recently, advances in echocardiography and magnetic resonance imaging have created new opportunities for the study of RV anatomy and physiology. The goal of the present review is to offer a clinical perspective on RV structure and function. In the first part, we discuss the anatomy, physiology, aging, and assessment of the RV. In the second part, we discuss the pathophysiology, clinical importance, and management of RV failure. ### Macroscopic Anatomy of the RV In the normal heart, the RV is the most anteriorly situated cardiac chamber and lies immediately behind the sternum. In the absence of transposition of great arteries, the RV is delimited by the annulus of the tricuspid valve and by the pulmonary valve. As suggested by Goor and Lillehi,4 the RV can be described in …

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Citations
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Journal ArticleDOI

Right ventricular function during and after thoracic surgery.

TL;DR: The most recent literature on RV dysfunction following lung resection is examined, including possible mechanisms, time span of RV dysfunction, and available diagnostic modalities, including cardiac MRI and new echocardiographic parameters.
Journal ArticleDOI

Right ventricular transverse displacement increases following cardiac surgery: possibly compensating loss in tricuspid annular plane systolic excursion (TAPSE).

TL;DR: Increased transverse displacement likely compensates for reduction in RV longitudinal contraction following cardiac surgery and maintains cardiac Output in Right Ventricular Echocardiography study.

Pulmonary Hypertension in Intensive Care Units: An Updated Review.

TL;DR: Clinicians should be familiar with the presentations of this disease and diagnostic tools, and vasopressors should be used to maintain systemic blood pressure, albeit cautiously, as they increase the RV afterload.
Journal ArticleDOI

Évaluation de la fraction d’éjection ventriculaire droite par la mesure du déplacement de l’anneau tricuspide via l’utilisation du tricuspid annular displacement (TAD)

TL;DR: This study is the first to correlate TAD with MRI RVEF, and shows that TAD is a simple, rapid, and non-invasive tool for right ventricular systolic function assessment.
References
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Journal ArticleDOI

ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

TL;DR: It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies as they are introduced in the detection, management, and management of diseases.
Journal ArticleDOI

Acute pulmonary embolism: clinical outcomes in the international cooperative pulmonary embolism registry (ICOPER)

TL;DR: Data from ICOPER provide rates and highlight adverse prognostic categories that will help in planning of future trials of high-risk PE patients and highlight significant prognostic factors associated with death.
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