Right Ventricular Function in Cardiovascular Disease, Part I Anatomy, Physiology, Aging, and Functional Assessment of the Right Ventricle
TLDR
The goal of the present review is to offer a clinical perspective on RV structure and function, using echocardiography and magnetic resonance imaging to create new opportunities for the study of RV anatomy and physiology.Abstract:
In 1616, Sir William Harvey was the first to describe the importance of right ventricular (RV) function in his seminal treatise, De Motu Cordis : “Thus the right ventricle may be said to be made for the sake of transmitting blood through the lungs, not for nourishing them.”1,2 For many years that followed, emphasis in cardiology was placed on left ventricular (LV) physiology, overshadowing the study of the RV. In the first half of the 20th century, the study of RV function was limited to a small group of investigators who were intrigued by the hypothesis that human circulation could function adequately without RV contractile function.3 Their studies, however, were based on an open pericardial dog model, which failed to take into account the complex nature of ventricular interaction. In the early 1950s through the 1970s, cardiac surgeons recognized the importance of right-sided function as they evaluated procedures to palliate right-heart hypoplasia. Since then, the importance of RV function has been recognized in heart failure, RV myocardial infarction, congenital heart disease and pulmonary hypertension. More recently, advances in echocardiography and magnetic resonance imaging have created new opportunities for the study of RV anatomy and physiology.
The goal of the present review is to offer a clinical perspective on RV structure and function. In the first part, we discuss the anatomy, physiology, aging, and assessment of the RV. In the second part, we discuss the pathophysiology, clinical importance, and management of RV failure.
### Macroscopic Anatomy of the RV
In the normal heart, the RV is the most anteriorly situated cardiac chamber and lies immediately behind the sternum. In the absence of transposition of great arteries, the RV is delimited by the annulus of the tricuspid valve and by the pulmonary valve. As suggested by Goor and Lillehi,4 the RV can be described in …read more
Citations
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Impact of right ventricular dysfunction on mortality in adults with cardiac arrest undergoing coronary angiogram.
TL;DR: In this observational contemporary study, RV dysfunction was independently associated with higher mortality in adults with CA undergoing coronary angiogram and may be useful for risk stratification and management in this high-mortality population.
Dissertation
Étude de la fonction vasculaire et du remodelage cardiaque avant l’établissement de l’obésité et de la dyslipidémie chez les rats femelles Sprague-Dawley recevant une diète riche en gras
TL;DR: L’administration orale chronique de l’antioxydant resveratrol (RES; 20 mg·kg-1·jr-1) a prevenu le developpement of ces alterations pathologiques, attestant d’une implication du stress oxydant.
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Recent advances in multimodality imaging of the tricuspid valve.
Sergio Caravita,Stefano Figliozzi,Diana-Ruxandra Florescu,Valentina Volpato,Giorgio Oliverio,Michele Tomaselli,Camilla Torlasco,Giuseppe Muscogiuri,Franco Cernigliaro,Gianfranco Parati,Luigi P. Badano,Denisa Muraru +11 more
TL;DR: In this article, the tricuspid valve and the right heart chambers are complex three-dimensional structures that are difficult to assess using tomographic imaging techniques, and the integrated use of multimodal cardiac imaging is pivotal to assess patients with TR and to identify tailored and timely treatment of TR in properly selected patients.
Journal ArticleDOI
Physiologie du couplage entre le ventricule droit et la circulation pulmonaire
TL;DR: In this article, a connaissance de la physiologie du couplage entre le ventricule droit (VD) and the circulation pulmonaire aide a mieux comprendre la physiopathologie des differentes maladies touchant le coeur droit and la circulation pulminaire.
Journal ArticleDOI
Usefulness of scoring right ventricular function for assessment of prognostic factors in patients with chronic thromboembolic pulmonary hypertension.
Yoshihiro Kamimura,Naoki Okumura,Shiro Adachi,Shigetake Shimokata,F. Tajima,Yoshihisa Nakano,Akihiro Hirashiki,Toyoaki Murohara,Takahisa Kondo +8 more
TL;DR: This RV dysfunction score using the four RV echocardiographic parameters could be a simple and useful scoring system to evaluate prognostic factors in patients with CTEPH.
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