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Journal ArticleDOI

Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials

TLDR
Drug treatment is justified in older patients with isolated systolic hypertension whose systolics blood pressure is 160 mm Hg or higher and in those with previous cardiovascular complications or wider pulse pressure, suggesting the coronary protection may have been underestimated.
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This article is published in The Lancet.The article was published on 2000-03-11. It has received 1159 citations till now. The article focuses on the topics: Blood pressure & Prehypertension.

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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.

TL;DR: Throughout middle and old age, usual blood pressure is strongly and directly related to vascular (and overall) mortality, without any evidence of a threshold down to at least 115/75 mm Hg.
References
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Book

Applied Logistic Regression

TL;DR: Hosmer and Lemeshow as discussed by the authors provide an accessible introduction to the logistic regression model while incorporating advances of the last decade, including a variety of software packages for the analysis of data sets.
Journal ArticleDOI

Applied Logistic Regression.

TL;DR: Applied Logistic Regression, Third Edition provides an easily accessible introduction to the logistic regression model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables.
Book

Statistical methods for rates and proportions

TL;DR: In this paper, the basic theory of Maximum Likelihood Estimation (MLE) is used to detect a difference between two different proportions of a given proportion in a single proportion.
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