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Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.
Abstract
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.

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Drug-induced anaphylaxis: a decade review of reporting to the Portuguese Pharmacovigilance Authority

TL;DR: In this series of drug-related anaphylaxis, it was found that most of the reported episodes were associated with widely used drugs, such as antibiotics and analgesics, and the female gender was more highly represented, with the exception of pediatric patients.
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Anaphylaxis management in the pediatric emergency department: opportunities for improvement.

TL;DR: This study is the first to describe the management of anaphylaxis in a pediatric emergency department of the Children's Hospital of Alabama and revealed opportunities for improvement.
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H1‐antihistamines for the treatment of anaphylaxis with and without shock

TL;DR: A review of Randomized and quasi-randomized controlled trials comparing H1-antihistamines with placebo or no intervention in the treatment of anaphylaxis found no studies that satisfied the inclusion criteria.
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Incidence and characteristics of biphasic reactions after allergen immunotherapy.

TL;DR: Biphasic reactions were significantly less severe compared with the initial reaction, did not occur in children, and did not require additional epinephrine.
References
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Journal ArticleDOI

Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents

TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.

TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis

TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
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Advances in H1-Antihistamines

TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.
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