Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
Citations
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An update on self-injectable epinephrine.
Susan A. Rudders,Aleena Banerji +1 more
TL;DR: It is suggested that all patients at risk for anaphylaxis should always carry two epinephrine doses and once an EAI is prescribed, the patient should receive appropriate education on when and how to use it and it should be administered without delay.
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H1-antihistamines Reduce Progression to Anaphylaxis Among Emergency Department Patients With Allergic Reactions.
Takahisa Kawano,Takahisa Kawano,Frank X. Scheuermeyer,Frank X. Scheuermeyer,Koichiro Gibo,Robert Stenstrom,Brian H. Rowe,Eric Grafstein,Eric Grafstein,Brian Grunau +9 more
TL;DR: It is indicated that early H1a treatment in the ED or prehospital setting may decrease progression to anaphylaxis, and among ED patient with allergic reactions, H 1a administration was associated with a lower likelihood of progression toAnaphylactic shock.
Journal ArticleDOI
Peanut allergy and allergic airways inflammation
TL;DR: Hughes JL, Brown T, Edgar JD, Shields MD: Peanut allergy and allergic airways inflammation.
Journal ArticleDOI
Improving Prehospital Protocol Adherence Using Bundled Educational Interventions.
Megan C Marino,Daniel G Ostermayer,Juan A. Mondragon,Elizabeth A. Camp,Elizabeth M. Keating,Louis B Fornage,Charles A Brown,Manish I. Shah +7 more
TL;DR: The use of a bundled, multifaceted educational intervention including in-person training, decision support tools, and social media improved adherence to updated evidence-based pediatric prehospital protocols.
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Epinephrine for anaphylaxis: underutilized and unavailable.
TL;DR: Broadened awareness of the need for emergent anaphylactic treatment with readily available epinephrine auto-injectors, analogous to the common awareness and use of publicly housed automated external defibrillators (AEDs) in cardiac arrest, may decrease the morbidity and mortality of this rapidly progressing disorder.
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
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Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
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Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.