Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
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Epidemiology of severe anaphylaxis: can we use population-based data to understand anaphylaxis?
Paul Turner,Dianne E. Campbell +1 more
TL;DR: An improved ability to accurately gather and analyse population-level anaphylaxis data in a harmonized fashion is required, so as to ultimately minimize risk and improve management.
Journal Article
Oral Immunotherapy in Children With IgE-Mediated Wheat Allergy: Outcome and Molecular Changes
Rodríguez del Río P,Araceli Díaz-Perales,Silvia Sanchez-Garcia,C. Escudero,do Santos P,Manuela Catarino,Ibáñez +6 more
TL;DR: The authors' wheat OIT protocol with wheat to treat IgE-mediated wheat-allergic children was safe, efficient, and rapid, and alpha-amylase inhibitors were recognized by all patients.
Journal ArticleDOI
Multinational experience with hypersensitivity drug reactions in Latin America
Edgardo Jares,Mario Sánchez-Borges,Ricardo Cardona-Villa,Luis Felipe Ensina,Alfredo Arias-Cruz,Maximiliano Gómez,Susana De Barayazarra,Jonathan A. Bernstein,Carlos Serrano,Mabel Noemi Cuello,Blanca María Morfin-Maciel,Alicia De Falco,Ivan Cherrez-Ojeda +12 more
TL;DR: Nonsteroidal anti-inflammatory drugs and antibiotics were the drugs used in at least 75% of patients, and more than half the reactions were treated in the emergency department, whereas epinephrine was administered in fewer than 25% of Patients with anaphylaxis.
Journal ArticleDOI
Food allergy: Stakeholder perspectives on acceptable risk
Charlotte Bernhard Madsen,René W.R. Crevel,C. H. Chan,Anthony E.J. Dubois,Audrey DunnGalvin,Bertine M. J. Flokstra-de Blok,M. Hazel Gowland,Sue Hattersley,Jonathan O'b Hourihane,Pia Nørhede,Sylvia Pfaff,Gene Rowe,Sabine Schnadt,Berber Vlieg-Boerstra +13 more
TL;DR: The perspectives of the different stakeholders (allergic consumers, health professionals, public authorities and the food industry) on acceptable risk in food allergy are discussed and where these perspectives diverge and even conflict may help develop an approach to define what is acceptable.
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Diagnostic Value of Tryptase in Food Allergic Reactions: A Prospective Study of 160 Adult Peanut Challenges
TL;DR: Serum tryptase measurement is valuable in food allergic reactions, and correlates with symptom severity, and the optimal cutoff to identify a reaction as a 30% rise is demonstrated.
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
Journal ArticleDOI
Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.