Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
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Treatment of patients who present after an episode of anaphylaxis.
TL;DR: This journal-based CME activity for amaximumof 1AMA PRA Category 1 Credit is designed to establish a differential diagnosis for patients presenting to their practice with symptoms suggestive of a previous anaphylactic episode and institute an effective treatment program to prevent recurrent episodes of anaphlyaxis.
Journal ArticleDOI
Tree Nut-Induced Anaphylaxis in Canadian Emergency Departments: Rate, Clinical Characteristics and Management.
Laurence Ducharme,Sofianne Gabrielli,Ann E. Clarke,Judy Morris,Jocelyn Gravel,Rod Lim,Edmond Chan,Ran D. Goldman,Andrew O'Keefe,Jennifer Gerdts,Derek K. Chu,Julia Upton,Elana Hochstadter,Adam Bretholz,Christine McCusker,Xun Zhang,Moshe Ben-Shoshan +16 more
TL;DR: In this article , the authors used multivariate logistic analysis to evaluate factors associated with severe reactions (stridor, cyanosis, circulatory collapse, or hypoxia) and epinephrine use.
Manejo actual de la anafilaxia
TL;DR: Las causas mas frecuentes de muerte relacionada with reacciones inmunes IgE son the penicilina parenteral, las picaduras de himenopteros y los alimentos, mientras que las sustancias empleadas para estudios de radiocontraste, the aspirina y otros medicamentos no esteroideos o los antiinflamatorios constituyen las
Dissertation
Mast cell activation disorders : a liaison between anaphylaxis and mastocytosis
TL;DR: These findings support that all patients with mast cell activation disorders should undergo comprehensive allergy work-up providing personal risk assessment before considering treatment and preventive measures and lend further support to the hypothesis of a clear-cut association between severe HVA and clonal mast cell disorders.
Journal ArticleDOI
Safety and efficacy of long‐term emicizumab prophylaxis in hemophilia A with factor VIII inhibitors: A phase 3b, multicenter, single‐arm study (STASEY)
Víctor Jiménez-Yuste,Flora Peyvandi,Robert Klamroth,Giancarlo Castaman,Chandrakala Shanmukhaiah,Savita Rangarajan,Jaime García Chavez,R. Martinez,Gili Kenet,Hazaa Alzahrani,Susan Robson,Christophe Schmitt,Anna Kiialainen,Oliver Meier,Margareth C. Ozelo +14 more
TL;DR: The bispecific monoclonal antibody emicizumab bridges activated factor IX and factor X, mimicking the cofactor function of activated factor VIII (FVIII), restoring hemostasis as discussed by the authors .
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
Journal ArticleDOI
Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
Journal ArticleDOI
Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
Journal ArticleDOI
Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.