Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
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Mas-related G protein-coupled receptors X (MRGPRX): Orphan GPCRs with potential as targets for future drugs.
Ghazl Al Hamwi,Yvonne Riedel,Sophie Clemens,Vigneshwaran Namasivayam,Dominik Thimm,Christa E. Müller +5 more
TL;DR: The recent elucidation of cryogenic electron microscopy structures of MRGPRX2 and -4 is expected to facilitate and advance drug development for these receptors, which have great potential as future drug targets.
Journal ArticleDOI
Managing side effects of the novel taxane cabazitaxel in castrate-resistant prostate cancer.
TL;DR: The vital role of nurses in identifying patients at high risk for AEs associated with cabazitaxel therapy is reviewed and strategies for prevention and management of symptoms are reviewed.
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Incidence of anaphylaxis and accidental peanut exposure: A systematic review.
TL;DR: In this article, a systematic literature review and meta-analysis was conducted to determine the incidence of peanut-induced anaphylaxis in children and/or adolescents with PA, where the authors used the I2 statistic as the measure of heterogeneity.
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Versorgung von Patienten mit Anaphylaxie — Möglichkeiten und Defizite
Knut Brockow,Kirsten Beyer,Tilo Biedermann,Jörg Fischer,Uwe Gieler,Oliver Giessler-Fichtner,N Gebert,Thilo Jakob,Ludger Klimek,Claudia Kugler,Imke Reese,Ernst Rietschel,Franziska Ruëff,Sabine Schnadt,Cäcilia Siemens,Rüdiger Szczepanski,Margitta Worm,Johannes Ring,Lars Lange +18 more
TL;DR: Die Anaphylaxie-Schulung hat in einem multizentrischen Projekt mit Kontrollgruppen eine signifikante Wirksamkeit in Bezug auf den Umgang mit dem Autoinjektor als lebensrettende Maßnahme and reduzierte Angst gezeigt.
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A case of anaphylaxis to palivizumab.
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
Journal ArticleDOI
Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.