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Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.
Abstract
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.

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One-year survey of paediatric anaphylaxis in an allergy department.

TL;DR: In the paediatric population, the main triggering agent of anaphylaxis was IgE-mediated food allergy andEpinephrine is underused, as reported by others.
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Long-term safety and efficacy of taliglucerase alfa in pediatric Gaucher disease patients who were treatment-naïve or previously treated with imiglucerase.

TL;DR: The findings extend the taliglucerase alfa safety and efficacy profile and demonstrate long-term clinical improvement in treatment-naïve children receiving taligluce alfa and maintenance of disease stability in children switched to taliglucine alfa.
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Food allergy endotype with high risk of severe anaphylaxis in children—Monosensitization to cashew 2S albumin Ana o 3

TL;DR: Food allergy in children can be life‐threatening and component‐resolved diagnostics approach to food anaphylaxis is rarely assessed in children.
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Heterogeneity in presentation and treatment of catamenial anaphylaxis.

TL;DR: Whether the mechanism causing cyclical anaphylaxis may involve hypersensitivity to progesterone or prostaglandins, the variable response to suppressive medications in these cases suggests that catamenial anAPHylaxis is a heterogeneous disorder in which a number of mechanisms and mediators may play a role.
References
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Journal ArticleDOI

Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents

TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.

TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis

TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
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Advances in H1-Antihistamines

TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.
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