Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
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Oncologic emergencies: Pathophysiology, presentation, diagnosis, and treatment
TL;DR: Oncologic emergencies can occur at any time during the course of a malignancy, from the presenting symptom to end‐stage disease, and prompt identification of and intervention in these emergencies can prolong survival and improve quality of life, even in the setting of terminal illness.
Journal ArticleDOI
Validation of the REMA Score for Predicting Mast Cell Clonality and Systemic Mastocytosis in Patients with Systemic Mast Cell Activation Symptoms
Iván Álvarez-Twose,David González-de-Olano,Laura Sánchez-Muñoz,Almudena Matito,María Jara-Acevedo,Cristina Teodosio,Andrés C. García-Montero,José Mário Morgado,Alberto Orfao,Luis Escribano +9 more
TL;DR: The clinical utility of the REMA score versus serum baseline tryptase (sBt) levels for predicting MC clonality and SM in patients suffering from systemic MC activation symptoms without MIS is confirmed.
Journal ArticleDOI
Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007.
TL;DR: Although most characteristics of peanut allergy have changed little over the period of the last 13 years (onset age, sex, comorbidity, severity, severity), later onset was associated with greater risk of anaphylaxis.
Journal ArticleDOI
Determining the negative predictive value of provocation tests with beta‐lactams
Pascal Demoly,Antonino Romano,Carmen Botelho,L. Bousquet-Rouanet,Francesco Gaeta,Rui Silva,G. Rumi,J. Rodrigues Cernadas,Philippe-Jean Bousquet +8 more
TL;DR: Determining the negative predictive value of provocation tests with beta‐lactams with Allergy 2010; 65: 327–332 is determined.
Journal ArticleDOI
Plasma contact system activation drives anaphylaxis in severe mast cell–mediated allergic reactions
Anna Sala-Cunill,Anna Sala-Cunill,Jenny Björkqvist,Riccardo Senter,Riccardo Senter,Mar Guilarte,Victoria Cardona,Moisés Labrador,Katrin F. Nickel,Katrin F. Nickel,Lynn M. Butler,Lynn M. Butler,Olga Luengo,Parvin Kumar,Linda Labberton,Andy T. Long,Antonio Di Gennaro,Ellinor Kenne,Anne Jämsä,Thorsten Krieger,Hartmut Schlüter,Tobias A. Fuchs,Tobias A. Fuchs,Stefanie Flohr,Ulrich Hassiepen,Frederic Cumin,Keith R. McCrae,Coen Maas,Evi X. Stavrou,Thomas Renné,Thomas Renné +30 more
TL;DR: In this paper, a plasma protease cascade, the factor XII-driven contact system, critically contributes to the pathogenesis of anaphylaxis in both murine models and human subjects.
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
Journal ArticleDOI
Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
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Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.