Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
Reads0
Chats0
TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
Citations
More filters
Journal ArticleDOI
Platelet-Activating Factor, PAF Acetylhydrolase, and Severe Anaphylaxis
Peter Vadas,Milton Gold,Boris Perelman,Gary M. Liss,Gideon Lack,Thomas Blyth,F. Estelle R. Simons,Keith J. Simons,Daniel Cass,Jupiter Yeung +9 more
TL;DR: Serum PAF levels were directly correlated and serum PAF acetylhydrolase activity was inversely correlated with the severity of anaphylaxis, and failure of PAf acetylHydrolase to inactivate PAF may contribute to the severity.
Journal ArticleDOI
Speaking the same language: The World Allergy Organization Subcutaneous Immunotherapy Systemic Reaction Grading System
TL;DR: A uniform classification system for grading SCIT SRs will be helpful in assessing more accurately when epinephrine should be administered, and may prevent the progression of an SR to a more serious life-threatening problem.
Journal ArticleDOI
Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group.
Phil Lieberman,Carlos A. Camargo,Kari Bohlke,Hershel Jick,Rachel L. Miller,Aziz Sheikh,F. Estelle R. Simons +6 more
TL;DR: A qualitative review by hand of the major epidemiology studies of anaphylaxis highlighted the importance of broader access to self-injectable epinephrine for high-risk populations and underdiagnosis, especially for those at highest risk.
Journal ArticleDOI
Anaphylaxis in children and adolescents: The European Anaphylaxis Registry
Linus Grabenhenrich,Sabine Dölle,Anne Moneret-Vautrin,Alice Köhli,Lars Lange,Thomas Spindler,F. Ruëff,Katja Nemat,Ioana Maris,Eirini Roumpedaki,Kathrin Scherer,Hagen Ott,Thomas S. Reese,Tihomir B. Mustakov,Roland Lang,Montserrat Fernandez-Rivas,Marek L. Kowalski,Maria Beatrice Bilò,Jonathan O'b Hourihane,Nikolaos G. Papadopoulos,Kirsten Beyer,Antonella Muraro,Margitta Worm +22 more
TL;DR: The European Anaphylaxis Registry (EAR) as mentioned in this paper is a registry for the identification and management of severe allergic reactions in children and adolescents in 10 European countries between 2007 and 2015.
Journal ArticleDOI
NCCN Guidelines ® Insights: Non-Small Cell Lung Cancer, Version 4.2016 Featured Updates to the NCCN Guidelines
David S. Ettinger,Douglas E. Wood,Wallace Akerley,Lyudmila Bazhenova,Hossein Borghaei,D.R. Camidge,Richard T. Cheney,Lucian R. Chirieac,Thomas A. D'Amico,Thomas J. Dilling,M. Chris Dobelbower,Ramaswamy Govindan,Mark Hennon,Leora Horn,Thierry Jahan,Ritsuko Komaki,Rudy P. Lackner,Michael Lanuti,Rogerio Lilenbaum,Jules Lin,Billy W. Loo,Renato G. Martins,Gregory A. Otterson,Jyoti D. Patel,Katherine M.W. Pisters,Karen L. Reckamp,Gregory J. Riely,Steven E. Schild,Theresa A. Shapiro,Neelesh Sharma,James P. Stevenson,Scott J. Swanson,Kurt Tauer,Stephen C. Yang,Kristina M. Gregory,Miranda Hughes +35 more
TL;DR: New immunotherapeutic agents, such as nivolumab and pembrolizumab, for patients with metastatic NSCLC are discussed, based on improved overall survival rates, higher response rates, longer duration of response, and fewer adverse events when compared with docetaxel therapy.
References
More filters
Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
Journal ArticleDOI
Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
Journal ArticleDOI
Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
Journal ArticleDOI
Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.