Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
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Patients' Satisfaction with Diagnostic Drug Provocation Tests and Perception of Its Usefulness
TL;DR: Most patients were satisfied with DPT for diagnostic purposes, and satisfaction with the procedure was independent of the results of the provocation tests and did not depend on the country.
Journal ArticleDOI
Long-term efficacy and safety of ixekizumab: A 5-year analysis of the UNCOVER-3 randomized controlled trial.
Andrew Blauvelt,Mark Lebwohl,Tomotaka Mabuchi,Ann Leung,Alyssa Garrelts,Heidi Crane,H. Elmaraghy,Himanshu Patel,Terri Ridenour,Kyoungah See,Gaia Gallo,Carle Paul +11 more
TL;DR: IXE demonstrates sustained efficacy and consistent safety through 264 weeks in patients using the approved dose over 5 years from UNCOVER-3.
Journal ArticleDOI
Bee and wasp stings in Deniyaya; a series of 322 cases.
E. W. R. A. Witharana,S. K. J. Wijesinghe,K S M Pradeepa,W. A. I. P. Karunaratne,Saroj Jayasinghe +4 more
TL;DR: Risk factors included day-time outdoor activities, occupation (tea plantation workers) and period of year, and the latter may be due to pollen season when the insects are found in abundance.
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Hospital admissions for anaphylaxis in Istanbul, Turkey.
TL;DR: This work aimed to estimate the frequency of anaphylaxis admissions to hospitals in Istanbul by estimating the number of patients treated for the disease in low‐ and middle‐income country settings.
Journal ArticleDOI
Improving Anaphylaxis Care: The Impact of a Clinical Pathway.
Juhee Lee,Bonnie Rodio,Jane Lavelle,Megan Lewis,Rachel English,Sarah Hadley,Jennifer Molnar,Cynthia Jacobstein,Antonella Cianferoni,Jonathan M. Spergel,Lisa Zielinski,Nicholas Tsarouhas,Terri F. Brown-Whitehorn +12 more
TL;DR: Reducing the recommended length of observation from 8 to 4 hours resulted in a near 60% reduction in the average rate of admission, and streamline the care of patients with anaphylaxis presenting to a busy pediatric ED, without any compromise in safety.
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
Journal ArticleDOI
Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.