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Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.
Abstract
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.

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Citations
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Medication errors in the management of anaphylaxis in a pediatric emergency department.

TL;DR: Use of an SOF significantly reduced the rate of dosage errors in the management of anaphylaxis and the number of medication errors was significantly reduced when the SOF was used.
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The time course of anaphylaxis manifestations in children is diverse and unpredictable.

TL;DR: The most current clinical definition of anaphylaxis is that proposed by Sampson et al. and different scoring systems have been proposed to assess its severity and underused by patients, families and even by health professionals.
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Quality‐of‐life issues in survivors to anaphylactic reactions to drugs

TL;DR: Compared with the Italian reference population, patients with drug‐induced anaphylaxis had a significantly reduced PGWBI total and domain score and the results highlight for the first time how impaired HRQoL and distress commonly feature in survivors toAnaphylactic reactions to drug.
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Consensus document on the approach to children with allergic reactions after vaccination or allergy to vaccine components

TL;DR: The usual vaccine components must be known in order to determine whether vaccination can be safely performed, and if a child with allergy to some of the vaccine components is scheduled for vaccination, a correct diagnosis of the possible allergic process must be made.
References
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Journal ArticleDOI

Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents

TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
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Fatalities due to anaphylactic reactions to foods.

TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis

TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
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Advances in H1-Antihistamines

TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.
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