Journal ArticleDOI
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Hugh A. Sampson,Anne Muñoz-Furlong,Ronna L. Campbell,N. Franklin Adkinson,S. Allan Bock,Amy M. Branum,Simon G A Brown,Carlos A. Camargo,Rita K. Cydulka,Stephen J. Galli,Jane Gidudu,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Robert E. O'Connor,Antonella Muraro,Amanda Rudman,Cara Schmitt,Debra Scherrer,F. Estelle R. Simons,Stephen Thomas,Joseph P. Wood,Wyatt W. Decker +25 more
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TLDR
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis, so representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition.Abstract:
There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network convened a second meeting on anaphylaxis, which included representatives from 16 different organizations or government bodies, including representatives from North America, Europe, and Australia, to continue working toward a universally accepted definition of anaphylaxis, establish clinical criteria that would accurately identify cases of anaphylaxis with high precision, further review the evidence on the most appropriate management of anaphylaxis, and outline the research needs in this area.read more
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Journal ArticleDOI
Fatal anaphylaxis with neuromuscular blocking agents: a risk factor and management analysis
M. Reitter,Nadine Petitpain,C. Latarche,Judith Cottin,N. Massy,Pascal Demoly,Pierre Gillet,Paul-Michel Mertes +7 more
TL;DR: Obese males with a history of cardiovascular disease receiving ongoing beta-blocker treatment and undergoing surgery in an emergency setting were at high risk of a fatal outcome after NMBA-induced anaphylaxis.
Journal ArticleDOI
Comparison of international guidelines for the emergency medical management of anaphylaxis.
M. Alrasbi,Aziz Sheikh +1 more
TL;DR: This study presents a meta-analysis of literature oneline‐based treatment approaches for managing anaphylaxis and found that these approaches are widely believed to result in good outcomes, but the strength of evidence underpinning the recommendations made therein is unclear.
Journal ArticleDOI
Efficacy and safety of oral immunotherapy with AR101 in European children with a peanut allergy (ARTEMIS): a multicentre, double-blind, randomised, placebo-controlled phase 3 trial
Jonathan O'b Hourihane,Jonathan O'b Hourihane,Kirsten Beyer,Allyah Abbas,Montserrat Fernandez-Rivas,Paul Turner,Katharina Blumchen,Caroline Nilsson,Maria D Ibáñez,Antoine Deschildre,Antonella Muraro,Vibha Sharma,Michel Erlewyn-Lajeunesse,José Manuel Zubeldia,Frédéric de Blay,Christine Sauvage,Aideen Byrne,John Chapman,Franck Boralevi,Audrey DunnGalvin,Charmaine O'Neill,David Norval,Andrea Vereda,Ben Skeel,Daniel C. Adelman,George Du Toit,George Du Toit +26 more
TL;DR: AR101 oral immunotherapy treatment led to rapid desensitisation to peanut protein, with a predictable safety profile that improved with treatment, and an associated improvement in self-reported and caregiver-reported food allergy-related quality of life.
Journal ArticleDOI
Anaphylaxis: Unique aspects of clinical diagnosis and management in infants (birth to age 2 years)
TL;DR: In this article, the authors aim to increase awareness of anaphylaxis in infancy in order to improve clinical diagnosis, management, and prevention of recurrences, which is increasingly reported in this age group.
Journal ArticleDOI
Inadvertent exposures in children with peanut allergy.
Nha Uyen Nguyen-Luu,Moshe Ben-Shoshan,Reza Alizadehfar,Lawrence Joseph,Laurie Harada,Mary Allen,Yvan St-Pierre,Ann E. Clarke +7 more
TL;DR: Inadvertent exposures in children with peanut allergy are found to be a cause for concern and research is needed to establish a causative mechanism.
References
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Journal ArticleDOI
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
TL;DR: Six children and adolescents who died of anaphylactic reactions to foods and seven others who nearly died and required intubation were identified and the failure to recognize the severity of these reactions and to administer epinephrine promptly increases the risk of a fatal outcome.
Journal ArticleDOI
Fatalities due to anaphylactic reactions to foods.
TL;DR: Fatal anaphylactic reactions to foods are continuing to occur, and better characterization might lead to better prevention, and peanuts and tree nuts accounted for more than 90% of the fatalities.
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Clinical features and severity grading of anaphylaxis
TL;DR: A simple grading system and definition of anaphylaxis has potential value for defining reaction severity in clinical practice and research settings and appears to be the major determinants of reaction severity.
Journal ArticleDOI
Symposium on the Definition and Management of Anaphylaxis: Summary report
Hugh A. Sampson,Anne Muñoz-Furlong,S. Allan Bock,Cara Schmitt,Robert Bass,Badrul A. Chowdhury,Wyatt W. Decker,Terence J. Furlong,Stephen J. Galli,David B.K. Golden,Rebecca S. Gruchalla,Allen D. Harlor,David L. Hepner,Marilyn Howarth,Allen P. Kaplan,Jerrold H. Levy,Lawrence M. Lewis,Phillip Lieberman,Dean D. Metcalfe,Ramon Murphy,Susan M. Pollart,Richard S. Pumphrey,Lanny J. Rosenwasser,F. Estelle R. Simons,Joseph P. Wood,Carlos A. Camargo +25 more
TL;DR: This dissertation aims to provide a history of medical marijuana use in the United States and Canada over a 40-year period from 1989 to 2002, with a focus on the period up to and including the year ending in 2002.
Journal ArticleDOI
Advances in H1-Antihistamines
TL;DR: There are clinically relevant differences among H1-antihistamines in their pharmacology and safety profiles in allergic rhinoconjunctivitis and chronic urticaria.