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Open AccessJournal ArticleDOI

Separation of Submicron Bioparticles by Dielectrophoresis

Hywel Morgan, +2 more
- 01 Jul 1999 - 
- Vol. 77, Iss: 1, pp 516-525
TLDR
With electrode arrays fabricated using direct write electron beam lithography, it is shown that different types of submicron latex spheres can be spatially separated and it is demonstrated that tobacco mosaic virus and herpes simplex virus can be manipulated and spatially separation in a microelectrode array.
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This article is published in Biophysical Journal.The article was published on 1999-07-01 and is currently open access. It has received 533 citations till now. The article focuses on the topics: Dielectrophoresis & Particle.

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Citations
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Journal ArticleDOI

Highlighting the uniqueness in dielectrophoretic enrichment of circulating tumor cells.

TL;DR: The potential of dielectrophoresis for CTCs enrichment is underlined and DEP has the potential of becoming a cytometric method for large‐scale sorting and characterization of cells.
Journal ArticleDOI

Dielectrophoretic isolation of cells using 3D microelectrodes featuring castellated blocks

TL;DR: These electrodes provide a more effective dielectrophoretic force field than thin-film surface electrodes and yet immobilize cells near stagnation points across a parabolic flow profile for enhanced cell viability and separation efficiency.
Journal ArticleDOI

Floating electrode dielectrophoresis.

TL;DR: Electrically floating electrodes are used in DEP devices and it is demonstrated that effective DEP forces can be achieved by using floating electrodes, which is expected to promote the use ofDEP devices in the manipulation of nanoparticles.
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Electrokinetic trapping and surface enhanced Raman scattering detection of biomolecules using optofluidic device integrated with a microneedles array.

TL;DR: In this study, microneedles which possess sharp tips were utilized to trap and detect the biomolecules and showed that the Raman signals of S. aureus were detected and greatly enhanced through SERS effect.
Journal ArticleDOI

Separation of sub-micron particles from micron particles using acoustic fluid relocation combined with acoustophoresis.

TL;DR: By combining acoustic fluid relocation with acoustophoresis, sub-micron particles can be effectively separated from micron particles at high flow rates and it can be further implemented to separate binary mixtures of micron particle if the volumetric ratio of two particles is greater than 10 and the larger particle diameter is about 10 μm.
References
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Book

CRC Handbook of Chemistry and Physics

TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Book

Electromechanics of Particles

TL;DR: In this paper, a detailed account of the electromechanical interactions that govern the behaviour of small particles when an electric or magnetic field is present is presented, with numerous real-world examples.
Journal ArticleDOI

Ac electrokinetics: a review of forces in microelectrode structures

TL;DR: In this article, the frequency dependency and magnitude of electrothermally induced fluid flow are discussed for low frequencies (up to 500 kHz) and the effects of Brownian motion, diffusion and buoyancy force are discussed in the context of the controlled manipulation of sub-micrometre particles.
Journal ArticleDOI

The Motion and Precipitation of Suspensoids in Divergent Electric Fields

TL;DR: In this article, it was shown that the phenomena of dielectrophoresis and dielectro-precipitation can be observed under rather ideal conditions, though it is ordinarily often difficult to do so because of the presence of the more easily produced electrophoreis or ion-type migration of charged particles.
Journal ArticleDOI

Separation of Human Breast Cancer Cells From Blood by Differential Dielectric Affinity

TL;DR: Findings indicate that the dielectric affinity technique may prove useful in a wide variety of cell separation and characterization applications.
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