Separation of Submicron Bioparticles by Dielectrophoresis
TLDR
With electrode arrays fabricated using direct write electron beam lithography, it is shown that different types of submicron latex spheres can be spatially separated and it is demonstrated that tobacco mosaic virus and herpes simplex virus can be manipulated and spatially separation in a microelectrode array.About:
This article is published in Biophysical Journal.The article was published on 1999-07-01 and is currently open access. It has received 533 citations till now. The article focuses on the topics: Dielectrophoresis & Particle.read more
Citations
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Journal ArticleDOI
Electrothermal flow effects in insulating (electrodeless) dielectrophoresis systems
Benjamin G. Hawkins,Brian Kirby +1 more
TL;DR: Electrothermal (ET) effects perturb the EO flow field, creating vorticity near the channel constriction and enhancing the deflection and trapping effects, and in almost all cases, ET effects enhance negative dielectrophoretic particle deflected and trapping phenomena.
Journal ArticleDOI
Microfluidic‐Based Approaches in Targeted Cell/Particle Separation Based on Physical Properties: Fundamentals and Applications
Rohollah Nasiri,Rohollah Nasiri,Amir Shamloo,Samad Ahadian,Leyla Amirifar,Javad Akbari,Marcus J. Goudie,KangJu Lee,Nureddin Ashammakhi,Mehmet R. Dokmeci,Dino Di Carlo,Ali Khademhosseini +11 more
TL;DR: In this article, the most commonly used label-free microfluidic-based cell separation methods are described and the challenges and perspectives to further develop such methods are discussed, as well as computational approaches complementing such methods.
Journal ArticleDOI
Aligning fast alternating current electroosmotic flow fields and characteristic frequencies with dielectrophoretic traps to achieve rapid bacteria detection
Zachary Gagnon,Hsueh-Chia Chang +1 more
TL;DR: The multiscale trap, with a typical trapping time of seconds for a dilute 70 µL volume of 103 particles per cc sample, is several orders of magnitude faster than conventional DEP traps and earlier AC‐EO traps with parallel, castellated, or finger electrodes.
Journal ArticleDOI
AC electrokinetics-enhanced capacitive immunosensor for point-of-care serodiagnosis of infectious diseases
Shanshan Li,Shanshan Li,Haochen Cui,Quan Yuan,Jie Wu,Ashutosh Wadhwa,Shigetoshi Eda,Hongyuan Jiang +7 more
TL;DR: The capacitive sensing method was shown to work with bovine sera to differentiate disease-positive samples from negative samples within 2 min, while conventional immunoassay would require multiple processing steps and take hours to complete.
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Acute On-Chip HIV Detection Through Label-Free Electrical Sensing of Viral Nano-Lysate
Hadi Shafiee,Muntasir Jahangir,Fatih Inci,ShuQi Wang,Remington B. M. Willenbrecht,Francoise Giguel,Athe M. N. Tsibris,Daniel R. Kuritzkes,Utkan Demirci +8 more
TL;DR: This study demonstrated for the first time a label-free electrical sensing method that can detect lysed viruses through impedance analysis, offering an alternative technology to the antibody-based methods such as dipsticks and Enzyme-linked Immunosorbent Assay (ELISA).
References
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Book
CRC Handbook of Chemistry and Physics
TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Book
Electromechanics of Particles
TL;DR: In this paper, a detailed account of the electromechanical interactions that govern the behaviour of small particles when an electric or magnetic field is present is presented, with numerous real-world examples.
Journal ArticleDOI
Ac electrokinetics: a review of forces in microelectrode structures
TL;DR: In this article, the frequency dependency and magnitude of electrothermally induced fluid flow are discussed for low frequencies (up to 500 kHz) and the effects of Brownian motion, diffusion and buoyancy force are discussed in the context of the controlled manipulation of sub-micrometre particles.
Journal ArticleDOI
The Motion and Precipitation of Suspensoids in Divergent Electric Fields
TL;DR: In this article, it was shown that the phenomena of dielectrophoresis and dielectro-precipitation can be observed under rather ideal conditions, though it is ordinarily often difficult to do so because of the presence of the more easily produced electrophoreis or ion-type migration of charged particles.
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Separation of Human Breast Cancer Cells From Blood by Differential Dielectric Affinity
Frederick F. Becker,Xiao-Bo Wang,Ying Huang,Ronald Pethig,Jody Vykoukal,Peter R. C. Gascoyne +5 more
TL;DR: Findings indicate that the dielectric affinity technique may prove useful in a wide variety of cell separation and characterization applications.