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Open AccessJournal ArticleDOI

Separation of Submicron Bioparticles by Dielectrophoresis

Hywel Morgan, +2 more
- 01 Jul 1999 - 
- Vol. 77, Iss: 1, pp 516-525
TLDR
With electrode arrays fabricated using direct write electron beam lithography, it is shown that different types of submicron latex spheres can be spatially separated and it is demonstrated that tobacco mosaic virus and herpes simplex virus can be manipulated and spatially separation in a microelectrode array.
About
This article is published in Biophysical Journal.The article was published on 1999-07-01 and is currently open access. It has received 533 citations till now. The article focuses on the topics: Dielectrophoresis & Particle.

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Citations
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Proceedings ArticleDOI

Micro- electrical impedance spectroscopy for particle detection

TL;DR: In this paper, a micro-electrical impedance spectroscopy detector for particle detection was proposed, and preliminary experiments were carried out using microelectrode pairs, and impedance spectra were compared with respect to opposite effects of dielectrophoresis and electrode polarization.
Journal ArticleDOI

Dynamic polarisation of a charged colloid in an oscillating electric field

TL;DR: In this paper, the complex polarisability of a single colloidal particle under an AC electric field, where the polarisation is affected by the zeta potential of the colloid, the diffusion constant of the ions, the thickness of the electric double layer, and the frequency of the AC field, was investigated.
Journal ArticleDOI

Determination of electrophysiological properties of human monocytes and THP-1 cells by dielectrophoresis

TL;DR: The dielectric properties for each type of cells can be used as the criteria in the development of DEP-based characterization assays and showed that THP-1 cells were physically larger than human monocytes.
Journal ArticleDOI

Numerical modelling and measurement of cell trajectories in 3-D under the influence of dielectrophoretic and hydrodynamic forces.

TL;DR: A 3‐D microstructure micro‐milled in a cyclic olefin copolymer was designed in such a way as to assemble liver cells via insulator‐based dielectrophoresis (iDEP) in a sinusoid‐type fashion to develop a fluidic microsystem for in vitro drug testing.
Dissertation

Non-Destructive Bio-Assay of Single Living Cell

TL;DR: The aim of this research is to investigate an innovative mechanism that enables to characterize, identify and differentiate among various living cells including malignant tumor cells through the use of the electromagnetic energy detection technique.
References
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Book

CRC Handbook of Chemistry and Physics

TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Book

Electromechanics of Particles

TL;DR: In this paper, a detailed account of the electromechanical interactions that govern the behaviour of small particles when an electric or magnetic field is present is presented, with numerous real-world examples.
Journal ArticleDOI

Ac electrokinetics: a review of forces in microelectrode structures

TL;DR: In this article, the frequency dependency and magnitude of electrothermally induced fluid flow are discussed for low frequencies (up to 500 kHz) and the effects of Brownian motion, diffusion and buoyancy force are discussed in the context of the controlled manipulation of sub-micrometre particles.
Journal ArticleDOI

The Motion and Precipitation of Suspensoids in Divergent Electric Fields

TL;DR: In this article, it was shown that the phenomena of dielectrophoresis and dielectro-precipitation can be observed under rather ideal conditions, though it is ordinarily often difficult to do so because of the presence of the more easily produced electrophoreis or ion-type migration of charged particles.
Journal ArticleDOI

Separation of Human Breast Cancer Cells From Blood by Differential Dielectric Affinity

TL;DR: Findings indicate that the dielectric affinity technique may prove useful in a wide variety of cell separation and characterization applications.
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