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Open AccessJournal ArticleDOI

Separation of Submicron Bioparticles by Dielectrophoresis

Hywel Morgan, +2 more
- 01 Jul 1999 - 
- Vol. 77, Iss: 1, pp 516-525
TLDR
With electrode arrays fabricated using direct write electron beam lithography, it is shown that different types of submicron latex spheres can be spatially separated and it is demonstrated that tobacco mosaic virus and herpes simplex virus can be manipulated and spatially separation in a microelectrode array.
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This article is published in Biophysical Journal.The article was published on 1999-07-01 and is currently open access. It has received 533 citations till now. The article focuses on the topics: Dielectrophoresis & Particle.

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Citations
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Journal ArticleDOI

The polarization of a nanoparticle surrounded by a thick electric double layer

TL;DR: The theoretical predictions are compared and favorably agree with experimental data, leading one to conclude that the standard, PNP based-model adequately represents the behavior of nanoparticles subject to electric fields.
Journal ArticleDOI

A rapid electrochemical biosensor based on an AC electrokinetics enhanced immuno-reaction

TL;DR: By integrating alternating current electrokinetics and electrochemical impedance spectroscopy, an immunochip is constructed for rapid, sensitive, and label-free detection and demonstrates excellent specificity for practical applications.
Journal ArticleDOI

Direct calculation of Maxwell stress tensor for accurate trajectory prediction during DEP for 2D and 3D structures

TL;DR: In this article, a robust numerical tool based on calculation of the Maxwell stress tensor (MST) both in a 2D and in a 3D formulation was developed to provide a deeper understanding of cells interaction using DEP as a handle to position and manipulate cells for fundamental cell biology.
Journal ArticleDOI

Large Area Patterning of Nanoparticles and Nanostructures: Current Status and Future Prospects

TL;DR: In this paper, a review of the parallel methods, materials that have been processed by them, and the types of particles that can be used with each method is presented, as well as the advantages and disadvantages of each method and challenges that still need to be addressed to enable facile, on-demand large-area nanopatterning.
Journal ArticleDOI

New trends in non-invasive prenatal diagnosis: applications of dielectrophoresis-based Lab-on-a-chip platforms to the identification and manipulation of rare cells.

TL;DR: DEP-based Lab-on-a-chip platforms have been demonstrated to be suitable for several applications in biotechnology and biomedicine, and are compatible with molecular interactions between monoclonal antibodies and target cells, allowing integration of these devices with magnetic cell sorting.
References
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Book

CRC Handbook of Chemistry and Physics

TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Book

Electromechanics of Particles

TL;DR: In this paper, a detailed account of the electromechanical interactions that govern the behaviour of small particles when an electric or magnetic field is present is presented, with numerous real-world examples.
Journal ArticleDOI

Ac electrokinetics: a review of forces in microelectrode structures

TL;DR: In this article, the frequency dependency and magnitude of electrothermally induced fluid flow are discussed for low frequencies (up to 500 kHz) and the effects of Brownian motion, diffusion and buoyancy force are discussed in the context of the controlled manipulation of sub-micrometre particles.
Journal ArticleDOI

The Motion and Precipitation of Suspensoids in Divergent Electric Fields

TL;DR: In this article, it was shown that the phenomena of dielectrophoresis and dielectro-precipitation can be observed under rather ideal conditions, though it is ordinarily often difficult to do so because of the presence of the more easily produced electrophoreis or ion-type migration of charged particles.
Journal ArticleDOI

Separation of Human Breast Cancer Cells From Blood by Differential Dielectric Affinity

TL;DR: Findings indicate that the dielectric affinity technique may prove useful in a wide variety of cell separation and characterization applications.
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