Journal ArticleDOI
Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study.
Feng Yee Chang,James E. Peacock,Daniel M. Musher,Patricia Triplett,Brent B. Macdonald,Joseph M. Mylotte,Alice O'donnell,Marilyn M. Wagener,Victor L. Yu +8 more
TLDR
Nafcillin was superior to vancomycin in preventing bacteriologic failure (persistent bacteremia or relapse) for methicillin-susceptible S. aureus (MSSA) baiteremia following antistaphylococcal therapy, and most were relapses.About:
This article is published in Medicine.The article was published on 2003-09-01. It has received 501 citations till now. The article focuses on the topics: Bacteremia & Vancomycin.read more
Citations
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Journal ArticleDOI
Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children
Catherine Liu,Arnold S. Bayer,Sara E. Cosgrove,Robert S. Daum,Scott K. Fridkin,Rachel J. Gorwitz,Sheldon L. Kaplan,Adolf W. Karchmer,Donald P. Levine,Barbara E. Murray,Michael J. Rybak,Henry F. Chambers +11 more
TL;DR: These guidelines discuss the management of a variety of clinical syndromes associated with MRSA disease, including skin and soft tissue infections (SSTI), bacteremia and endocarditis, pneumonia, bone and joint infections, and central nervous system infections.
Journal ArticleDOI
Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
TL;DR: This review comprehensively covers the epidemiology, pathophysiology, clinical manifestations, and management of S. aureus as a leading cause of bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device-related infections.
Journal ArticleDOI
Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by Staphylococcus aureus
Vance G. Fowler,Helen W. Boucher,G. Ralph Corey,Elias Abrutyn,Adolf W. Karchmer,Mark E. Rupp,Donald P. Levine,Henry F. Chambers,Francis P. Tally,Gloria Vigliani,Christopher H. Cabell,Arthur Stanley Link,Ignace DeMeyer,Scott G. Filler,Marcus J. Zervos,Paul P. Cook,Jeffrey Parsonnet,Jack M. Bernstein,Connie S. Price,Graeme N. Forrest,Gerd Fätkenheuer,Marcelo Gareca,Susan J. Rehm,Hans Reinhardt Brodt,Alan D. Tice,Sara E. Cosgrove +25 more
TL;DR: Daptomycin (6 mg per kilogram daily) is not inferior to standard therapy for S. aureus bacteremia and right-sided endocarditis and met prespecified criteria for the noninferiority of daptomecin.
Journal ArticleDOI
Reduced Vancomycin Susceptibility in Staphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications
Benjamin P Howden,John K. Davies,Paul D R Johnson,Paul D R Johnson,Timothy P. Stinear,Timothy P. Stinear,M Lindsay Grayson,M Lindsay Grayson +7 more
TL;DR: It is now becoming clear that sequential point mutations in key global regulatory genes contribute to the hVISA and VISA phenotypes, which are associated predominately with cell wall thickening and restricted vancomycin access to its site of activity in the division septum.
Journal ArticleDOI
Epidemiology of Methicillin-Resistant Staphylococcus aureus
Helen W. Boucher,G. Ralph Corey +1 more
TL;DR: The trends in both nosocomial and community-associated MRSA infections are examined and recent studies of the mechanisms that allow S. aureus to become resistant to currently available drugs are explored.
References
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Journal ArticleDOI
Relationship of staphylococcal tolerance, teichoic acid antibody, and serum bactericidal activity to therapeutic outcome in Staphylococcus aureus bacteremia
TL;DR: The results suggest that neither clinical nor immunologic methods can reliably detect complications in patients treated for two weeks only, and patients infected with tolerant organisms remained febrile longer than those infected with nontolerant strains but did not require additional antibiotics for cure.
Journal ArticleDOI
Home Intravenous Antibiotic Therapy Using a Programmable Infusion Pump
TL;DR: The development of a computerized ambulatory infusion drug delivery pump has enabled patients previously considered ineligible for home intravenous antibiotic therapy to be treated at home with the infusion pump.
Journal ArticleDOI
Tolerant Staphylococcus aureus causing vertebral osteomyelitis.
Daniel M. Musher,Taylor Fletcher +1 more
TL;DR: Bacterial tolerance in this case appeared to be responsible for the failure of vertebral osteomyelitis to be cured by accepted therapy with beta-lactam antibiotics.
Related Papers (5)
Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by Staphylococcus aureus
Vance G. Fowler,Helen W. Boucher,G. Ralph Corey,Elias Abrutyn,Adolf W. Karchmer,Mark E. Rupp,Donald P. Levine,Henry F. Chambers,Francis P. Tally,Gloria Vigliani,Christopher H. Cabell,Arthur Stanley Link,Ignace DeMeyer,Scott G. Filler,Marcus J. Zervos,Paul P. Cook,Jeffrey Parsonnet,Jack M. Bernstein,Connie S. Price,Graeme N. Forrest,Gerd Fätkenheuer,Marcelo Gareca,Susan J. Rehm,Hans Reinhardt Brodt,Alan D. Tice,Sara E. Cosgrove +25 more