Journal ArticleDOI
Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study.
Feng Yee Chang,James E. Peacock,Daniel M. Musher,Patricia Triplett,Brent B. Macdonald,Joseph M. Mylotte,Alice O'donnell,Marilyn M. Wagener,Victor L. Yu +8 more
TLDR
Nafcillin was superior to vancomycin in preventing bacteriologic failure (persistent bacteremia or relapse) for methicillin-susceptible S. aureus (MSSA) baiteremia following antistaphylococcal therapy, and most were relapses.About:
This article is published in Medicine.The article was published on 2003-09-01. It has received 501 citations till now. The article focuses on the topics: Bacteremia & Vancomycin.read more
Citations
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Journal ArticleDOI
Reversible Antibiotic Tolerance Induced in Staphylococcus aureus by Concurrent Drug Exposure
Jakob Haaber,Jakob Haaber,Cathrine Friberg,Mark McCreary,Richard Z. Lin,Stanley N. Cohen,Hanne Ingmer +6 more
TL;DR: It is shown that phenotypic resistance can arise where changes in gene expression result in tolerance to an antibiotic without any accompanying genetic changes, and that methicillin-resistant Staphylococcus aureus behaves like vancomycin-intermediate S. aUREus (VISA) upon exposure to colistin, which is currently used against infections by Gram-negative bacteria.
Journal ArticleDOI
Can β-lactams be re-engineered to beat MRSA?
TL;DR: Finding viable PBP2′-active β-lactams has proved difficult and the catalogue of near-misses extends back to the 1980s, but one cephalosporin with high affinity for P BP2′—ceftobiprole—is entering phase III trials.
Journal ArticleDOI
Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model.
Karoline Sidelmann Brinch,Anne Sandberg,Pierre Baudoux,Françoise Van Bambeke,Paul M. Tulkens,Niels Frimodt-Møller,Niels Høiby,Hans-Henrik Kristensen +7 more
TL;DR: The in vitro model was a good screening model for intracellular activity and animal models should be applied if further information on activity, PK/pharmacodynamic parameters, and optimal dosing regimens is required, since these features cannot be predicted from traditional MIC and killing kinetic studies.
Journal ArticleDOI
Treatment of Methicillin-Resistant Staphylococcus aureus: Vancomycin and Beyond
Natasha E Holmes,Steven Y. C. Tong,Joshua S. Davis,Sebastiaan J. van Hal,Sebastiaan J. van Hal +4 more
TL;DR: There has been a welcome increase in the number of agents available for the treatment of methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin remains an acceptable treatment option, with moves toward individualized dosing to a pharmacokinetic/pharmacodynamic (PK/PD) target.
Journal ArticleDOI
Clinical consensus conference: survey on Gram-positive bloodstream infections with a focus on Staphylococcus aureus
Christoph Naber,Larry M. Baddour,Evangelos J. Giamarellos-Bourboulis,Ian M. Gould,Mathias Herrmann,Bruno Hoen,Adolf W. Karchmer,Yoshio Kobayashi,R. S. Kozlov,Daniel Pablo Lew,Miró Jm,Robert C. Moellering,Philippe Moreillon,Georg Peters,Ethan Rubinstein,Harald Seifert,G. R. Corey +16 more
TL;DR: The Clinical Consensus Conference on Gram-Positive Bloodstream Infections was convened as a session at the 9th International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections, and participants discussed various aspects of the practical treatment of patients who present with gram-positive BSI.
References
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Journal ArticleDOI
Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.
Fred C. Tenover,Robert D. Arbeit,Richard V. Goering,P. A. Mickelsen,Barbara E Murray,D. H. Persing,B. Swaminathan +6 more
TL;DR: This research presents a novel, scalable and scalable approach that allows for real-time assessment of the severity of the infection and its impact on patients’ health.
Journal ArticleDOI
CDC definitions for nosocomial infections, 1988
TL;DR: The Centers for Disease Control (CDC) developed a new set of definitions for surveillance of nosocomial infections as mentioned in this paper, which combine specific clinical findings with results of laboratory and other tests that include recent advances in diagnostic technology.
Journal ArticleDOI
The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults.
William A. Knaus,Douglas P. Wagner,Elizabeth A. Draper,Jack E. Zimmerman,Marilyn Bergner,Paulo G. Bastos,Carl A. Sirio,Donaldj Murphy,Ted Lotring,Anne M. Damiano +9 more
TL;DR: The overall predictive accuracy of the first-day APACHE III equation was such that, within 24 h ofICU admission, 95 percent of ICU admissions could be given a risk estimate for hospital death that was within 3 percent of that actually observed.
Journal ArticleDOI
New criteria for diagnosis of infective endocarditis : Utilization of specific echocardiographic findings. Duke Endocarditis Service
TL;DR: Application of the proposed new criteria increases the number of definite diagnoses and should be useful for more accurate diagnosis and classification of patients with suspected endocarditis and provide better entry criteria for epidemiologic studies and clinical trials.
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Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by Staphylococcus aureus
Vance G. Fowler,Helen W. Boucher,G. Ralph Corey,Elias Abrutyn,Adolf W. Karchmer,Mark E. Rupp,Donald P. Levine,Henry F. Chambers,Francis P. Tally,Gloria Vigliani,Christopher H. Cabell,Arthur Stanley Link,Ignace DeMeyer,Scott G. Filler,Marcus J. Zervos,Paul P. Cook,Jeffrey Parsonnet,Jack M. Bernstein,Connie S. Price,Graeme N. Forrest,Gerd Fätkenheuer,Marcelo Gareca,Susan J. Rehm,Hans Reinhardt Brodt,Alan D. Tice,Sara E. Cosgrove +25 more