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Journal ArticleDOI

Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study.

TLDR
Nafcillin was superior to vancomycin in preventing bacteriologic failure (persistent bacteremia or relapse) for methicillin-susceptible S. aureus (MSSA) baiteremia following antistaphylococcal therapy, and most were relapses.
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This article is published in Medicine.The article was published on 2003-09-01. It has received 501 citations till now. The article focuses on the topics: Bacteremia & Vancomycin.

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Citations
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Journal ArticleDOI

Cationic Antimicrobial Peptide LL-37 Is Effective against both Extra- and Intracellular Staphylococcus aureus

TL;DR: LL-37 was shown to be very potent and prompt in eliminating both extra- and intracellular S. aureus and was more effective in killing extra-and-injury-free S.Aureus than commonly used conventional antibiotics.
Journal ArticleDOI

Impact of Empirical-Therapy Selection on Outcomes of Intravenous Drug Users with Infective Endocarditis Caused by Methicillin-Susceptible Staphylococcus aureus

TL;DR: Patients who received vancomycin had higher infection-related mortality, even if they were switched to beta-lactam once culture results became available, and this relationship persisted after logistic regression analysis controlling for clinical characteristics.
Journal ArticleDOI

Development of a real-time Staphylococcus aureus and MRSA (SAM-) PCR for routine blood culture.

TL;DR: A duplex real-time TaqMan polymerase chain reaction targeting the species-specific nuc gene, and the mecA gene encoding methicillin-resistance, was developed as a tool for rapid identification and detection of S. aureus in mixed infection, and identified Methicillin resistance in both S. epidermidis and S.Aureus strains.
Journal ArticleDOI

Treatment Duration for Uncomplicated Staphylococcus aureus Bacteremia To Prevent Relapse: Analysis of a Prospective Observational Cohort Study

TL;DR: It seems reasonable to consider at least 14 days of antibiotic therapy to prevent relapse in the treatment of uncomplicated SAB, as practice guidelines recommend.
References
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Journal ArticleDOI

Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.

TL;DR: This research presents a novel, scalable and scalable approach that allows for real-time assessment of the severity of the infection and its impact on patients’ health.
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CDC definitions for nosocomial infections, 1988

TL;DR: The Centers for Disease Control (CDC) developed a new set of definitions for surveillance of nosocomial infections as mentioned in this paper, which combine specific clinical findings with results of laboratory and other tests that include recent advances in diagnostic technology.
Journal ArticleDOI

The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults.

TL;DR: The overall predictive accuracy of the first-day APACHE III equation was such that, within 24 h ofICU admission, 95 percent of ICU admissions could be given a risk estimate for hospital death that was within 3 percent of that actually observed.
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New criteria for diagnosis of infective endocarditis : Utilization of specific echocardiographic findings. Duke Endocarditis Service

TL;DR: Application of the proposed new criteria increases the number of definite diagnoses and should be useful for more accurate diagnosis and classification of patients with suspected endocarditis and provide better entry criteria for epidemiologic studies and clinical trials.
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