Journal ArticleDOI
Surface characteristics and hemocompatibility of PAN/PVDF blend membranes
TLDR
In this article, polyacrylonitrile (PAN) was blended with polyvinylidine fluoride (PVDF) at various ratios and made into membranes, and the hemocompatibility of the resulting membranes was evaluated based on human plasma proteins adsorption, platelet adhesion, thrombus formation, and blood coagulation time.Abstract:
Polyacrylonitrile (PAN) was blended with polyvinylidine fluoride (PVDF) at various ratios and made into membranes. The hemocompatibility of the resulting membranes was evaluated based on human plasma proteins adsorption, platelet adhesion, thrombus formation, and blood coagulation time. The PAN/PVDF blends exhibited partial miscibility according to the inward shifting of their two glass transition temperatures. The microstructures of blend membranes examined using atomic force microscopy (AFM) indicated that the roughness increased with the PVDF content, and the phase separation was too severe to form a membrane when the PVDF content was more than 30%. The water contact angle of PAN/PVDF blend membranes increased with the PVDF content. By blending with 20wt% apolar PVDF the adsorption of blood proteins could be reduced, and hence the platelet adhesion and thrombus formation was also reduced. However, when the PVDF content was 30wt%, severe thrombogenicity was observed due probably to the more porous structure of blend membrane. These results demonstrated that the hemocompatibility would be improved for PAN/PVDF blend membranes with appropriate hydrophilicity and roughness. Copyright # 2005 John Wiley & Sons, Ltd.read more
Citations
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Application and modification of poly(vinylidene fluoride) (PVDF) membranes – A review
Guodong Kang,Yiming Cao +1 more
TL;DR: An overview of recent progress on the application and modification of polyvinylidene fluoride (PVDF) membranes can be found in this article, where two major problems of PVDF membranes in applications, namely membrane fouling and membrane wetting, are comprehensively reviewed.
Journal ArticleDOI
Long-term safety of drug-eluting and bare-metal stents: Evidence from a comprehensive network meta-analysis
Tullio Palmerini,Umberto Benedetto,Giuseppe Biondi-Zoccai,Diego Della Riva,Letizia Bacchi-Reggiani,Pieter C. Smits,Georgios J. Vlachojannis,Lisette Okkels Jensen,Evald Høj Christiansen,Klara Berencsi,Marco Valgimigli,Carlotta Orlandi,Mario Petrou,Claudio Rapezzi,Gregg W. Stone +14 more
TL;DR: Among DES, second- generation devices have substantially improved long-term safety and efficacy outcomes compared with first-generation devices.
Journal ArticleDOI
Development of electrospun PVdF-PAN membrane-based polymer electrolytes for lithium batteries
A. I. Gopalan,Padmanabhan Santhosh,Kalayil Manian Manesh,Jin Hee Nho,Sang-Ho Kim,Chul-Gyun Hwang,Kwang-Pill Lee +6 more
TL;DR: In this article, the morphology of polyvinylidene fluoride and polyacrylonitrile (PVdF-PAN-ESFMs) was examined by field emission scanning electron microscopy (FESEM).
Journal ArticleDOI
Clinical Outcomes With Bioabsorbable Polymer- Versus Durable Polymer-Based Drug-Eluting and Bare-Metal Stents: Evidence From a Comprehensive Network Meta-Analysis
Tullio Palmerini,Giuseppe Biondi-Zoccai,Diego Della Riva,Andrea Mariani,Manel Sabaté,Pieter C. Smits,Christoph Kaiser,Fabrizio D'Ascenzo,Giacomo Frati,Massimo Mancone,Philippe Généreux,Gregg W. Stone +11 more
TL;DR: In this large-scale network meta-analysis, BP-BES were associated with superior clinical outcomes compared with BMS and first-generation DES and similar rates of cardiac death/MI, MI, and TVR compared with second-generation DP-DES but higher rates of definite ST than CoCr-EES.
Journal ArticleDOI
A prospective, randomized evaluation of a novel everolimus-eluting coronary stent: the PLATINUM (a Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System [PROMUS Element] for the Treatment of Up to Two de Novo Coronary Artery Lesions) trial.
Gregg W. Stone,Paul S. Teirstein,Ian T. Meredith,Bruno Farah,Christophe Dubois,Robert L. Feldman,Joseph Dens,Nobuhisa Hagiwara,Dominic J. Allocco,Keith D. Dawkins,Platinum Trial Investigators +10 more
TL;DR: In this large-scale, prospective, single-blind randomized trial, a novel PtCr-EES was noninferior to the predicate CoCr- EES for TLF, with nonsignificant differences in measures of safety and efficacy through 12-month follow-up after PCI.
References
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Hemocompatibility of polyacrylonitrile dialysis membrane immobilized with chitosan and heparin conjugate.
TL;DR: PEC-immobilization can endow the PAN membrane hemocompatibility and antibacterial activity while retaining the original permeability, and the pure water permeability results show little variation due to PEC-IMobilization.
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Synthesis and characterization of heparinized polyurethanes using plasma glow discharge.
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