TBP, a universal eukaryotic transcription factor ?
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This article is published in Genes & Development.The article was published on 1993-07-01 and is currently open access. It has received 583 citations till now. The article focuses on the topics: Eukaryotic transcription & TATA-binding protein.read more
Citations
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The general transcription factors of RNA polymerase II.
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The general transcription machinery and general cofactors.
Mary C. Thomas,Cheng Ming Chiang +1 more
TL;DR: These cofactors are capable of repressing basal transcription when activators are absent and stimulating transcription in the presence of activators, with emphasis on the events occurring after the chromatin has been remodeled but prior to the formation of the first phosphodiester bond.
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Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
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Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery
TL;DR: This review focuses on the global effectors of RNA polymerase II transcription in yeast, including the general transcription factors, the coactivators, and the general repressors.
References
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A novel genetic system to detect protein-protein interactions.
Stanley Fields,Ok-kyu Song +1 more
TL;DR: A novel genetic system to study protein-protein interactions between two proteins by taking advantage of the properties of the GAL4 protein of the yeast Saccharomyces cerevisiae, which may be applicable as a general method to identify proteins that interact with a known protein by the use of a simple galactose selection.
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Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein.
TL;DR: A sequence within the transcription control region of the adeno-associated virus P5 promoter has been shown to mediate transcriptional activation by the adenovirus E1A protein, and it is reported here that this same element mediates transcriptional repression in the absence of E 1A.
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Five intermediate complexes in transcription initiation by RNA polymerase II
TL;DR: A native gel electrophoresis DNA binding assay was used to resolve complexes formed on the adenovirus Major Late Promoter by general transcription factors and RNA polymerase II, generating new complexes that contained accurately initiated transcripts associated with the transcription machinery and the template DNA.
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Mechanism of transcriptional activation by Sp1: evidence for coactivators.
B. Franklin Pugh,Robert Tjian +1 more
TL;DR: These findings with Sp1 and CTF suggest that partially purified TFIID fractions from human and Drosophila cells contain coactivators that are dispensable for basal transcription but are required as molecular adaptors between trans-activators and the general transcription initiation machinery.
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Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation
TL;DR: Results suggest that one or more of the TAF polypeptides confer coactivator function in NTF-1, a developmentally regulated transcription factor in Drosophila.