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The design and analysis of experiments.
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Pentobarbital sodium - Variation in toxicity.
Hugh A. Lindsay,V. S. Kullman +1 more
TL;DR: The survival rate of groups of female mice given a standard dose of pentobarbital sodium varied during a 12-hour period, when survival rate was plotted against time, a curve with several inflections was described.
Book ChapterDOI
Non-Inferiority Trials
TL;DR: In this paper, the authors focus on the challenges presented by therapeutic targets in the central nervous system (CNS), the manner in which animal models have and can be used to support the translation of therapeutic biologies to the human CNS, the blood brain barrier (BBB), and the uncertainties of CNS drug exposures.
Journal ArticleDOI
Orthogonal Main-Effect 2 n 3 m Designs and Two-Factor Interaction Aliasing
TL;DR: In this article, the alias matrix of two-factor interactions for the orthogonal main-effect 2 n 3 m plans catalogued by Addelman and Kempthorne is derived.
Journal ArticleDOI
Herbage allowance and intake of cattle
TL;DR: Rates of intake of herbage and grazing time of beef cattle are essential components of simulation models of grassland agroecosystems and intake of cattle grazing vegetative temperate grass swards appears to be ca.