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The Effects of Poverty on Childhood Brain Development: The Mediating Effect of Caregiving and Stressful Life Events

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TLDR
The finding that exposure to poverty in early childhood materially impacts brain development at school age further underscores the importance of attention to the well-established deleterious effects of poverty on child development.
Abstract: 
DESIGN, SETTING, AND PARTICIPANTS This study was conducted at an academic research unit at the Washington University School of Medicine in St Louis. Data from a prospective longitudinal study of emotion development in preschool children who participated in neuroimaging at school age were used to investigate the effects of poverty on brain development. Children were assessed annually for 3 to 6 years prior to the time of a magnetic resonance imaging scan, during which they were evaluated on psychosocial, behavioral, and other developmental dimensions. Preschoolers included in the study were 3 to 6 years of age and were recruited from primary care and day care sites in the St Louis metropolitan area; they were annually assessed behaviorally for 5 to 10 years. Healthy preschoolers and those with clinical symptoms of depression participated in neuroimaging at school age/early adolescence.

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Dissertation

Neuroimmune and Developmental Mechanisms Regulating Motivational Behaviors for Opioids

TL;DR: In this paper, Lacagnina et al. describe the neuroimmune and developmental Mechanisms Regulating Motivational Behaviors for Opioids by Michael J. Lacagnna.
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When trauma hinders learning

Donald A. Barr
- 26 Feb 2018 - 
TL;DR: Many kindergarten teachers have encountered children who enter school lacking the ability to control their behavior, but they may not understand the social and biological processes behind these children's behavior as discussed by the authors...
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Socioeconomic and experiential influences on the neurobiology of language development

TL;DR: A specific focus is given to the burgeoning neuroimaging evidence of relationships between socioeconomic status (SES) and brain development, as well as to emerging research on proximal experiences that may serve as the direct mechanisms by which SES influences language development.
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Poverty and Child Maltreatment

TL;DR: The authors reviewed current knowledge around child maltreatment and poverty and concluded that poverty is not only associated with maltreatment, but also a causal factor, and that any large gains in reducing maltreatment will come at least in part through socioeconomically oriented interventions or policies.
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State-level macro-economic factors moderate the association of low income with brain structure and mental health in U.S. children

TL;DR: In this paper , the authors leveraged data from the Adolescent Brain and Cognitive Development (ABCD) study from 10,633 9-11 year old youth across 17 states and found that lower income was associated with smaller hippocampal volume and higher internalizing psychopathology.
References
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Book

Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach

TL;DR: In this paper, the authors present a discussion of whether, if, how, and when a moderate mediator can be used to moderate another variable's effect in a conditional process analysis.
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Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models

TL;DR: An overview of simple and multiple mediation is provided and three approaches that can be used to investigate indirect processes, as well as methods for contrasting two or more mediators within a single model are explored.
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A comparison of methods to test mediation and other intervening variable effects.

TL;DR: A Monte Carlo study compared 14 methods to test the statistical significance of the intervening variable effect and found two methods based on the distribution of the product and 2 difference-in-coefficients methods have the most accurate Type I error rates and greatest statistical power.
BookDOI

From Neurons to Neighborhoods: The Science of Early Childhood Development

TL;DR: From Neurons to Neighborhoods as discussed by the authors presents the evidence about "brain wiring" and how children learn to learn to speak, think, and regulate their behavior, and examines the effect of the climate-family, child care, community-within which the child grows.
Journal ArticleDOI

Meaningful Differences in the Everyday Experience of Young American Children

TL;DR: Hart and Risley the authors, 1995, the authors ) discuss the effects of gender stereotypes on women's reproductive health and sexual health, and propose a method to improve women's health.
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