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The Effects of Poverty on Childhood Brain Development: The Mediating Effect of Caregiving and Stressful Life Events

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TLDR
The finding that exposure to poverty in early childhood materially impacts brain development at school age further underscores the importance of attention to the well-established deleterious effects of poverty on child development.
Abstract
DESIGN, SETTING, AND PARTICIPANTS This study was conducted at an academic research unit at the Washington University School of Medicine in St Louis. Data from a prospective longitudinal study of emotion development in preschool children who participated in neuroimaging at school age were used to investigate the effects of poverty on brain development. Children were assessed annually for 3 to 6 years prior to the time of a magnetic resonance imaging scan, during which they were evaluated on psychosocial, behavioral, and other developmental dimensions. Preschoolers included in the study were 3 to 6 years of age and were recruited from primary care and day care sites in the St Louis metropolitan area; they were annually assessed behaviorally for 5 to 10 years. Healthy preschoolers and those with clinical symptoms of depression participated in neuroimaging at school age/early adolescence.

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The role of ethnicity and socioeconomic status in Southeast Asian mothers' parenting sensitivity.

TL;DR: This paper assessed parenting behavior in 293 Singaporean citizen mothers of 6-month olds (153 Chinese, 108 Malay, 32 Indian) via the Maternal Behavioral Q-sort for video interactions.
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Childhood socio-economic disadvantage predicts reduced myelin growth across adolescence and young adulthood

TL;DR: Early socio-economic disadvantage, a vulnerability factor for a range of ill-health outcomes, is a risk factor for aberrant myelin growth during a critical developmental period that is associated with a high risk of psychiatric disorder.
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Examining how rural ecological contexts influence children’s early learning opportunities

TL;DR: This article found that children in one rural state experienced diversity in ecological systems that may impact their opportunities for learning, in particular the level of familial poverty, early education access, family-school engagement, available community resources, and cultural diversity in these rural communities.
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The Impact of the in utero and Early Postnatal Environments on Grey and White Matter Volume: A Study with Adolescent Monozygotic Twins.

TL;DR: It is found that the BW was significantly associated with the total GM and WM volumes, particularly in the superior frontal gyrus and thalamus, supporting the hypothesis that the specific in utero environment is associated with brain development independently of genetics.
References
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Book

Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach

TL;DR: In this paper, the authors present a discussion of whether, if, how, and when a moderate mediator can be used to moderate another variable's effect in a conditional process analysis.
Journal ArticleDOI

Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models

TL;DR: An overview of simple and multiple mediation is provided and three approaches that can be used to investigate indirect processes, as well as methods for contrasting two or more mediators within a single model are explored.
Journal ArticleDOI

A comparison of methods to test mediation and other intervening variable effects.

TL;DR: A Monte Carlo study compared 14 methods to test the statistical significance of the intervening variable effect and found two methods based on the distribution of the product and 2 difference-in-coefficients methods have the most accurate Type I error rates and greatest statistical power.
BookDOI

From Neurons to Neighborhoods: The Science of Early Childhood Development

TL;DR: From Neurons to Neighborhoods as discussed by the authors presents the evidence about "brain wiring" and how children learn to learn to speak, think, and regulate their behavior, and examines the effect of the climate-family, child care, community-within which the child grows.
Journal ArticleDOI

Meaningful Differences in the Everyday Experience of Young American Children

TL;DR: Hart and Risley the authors, 1995, the authors ) discuss the effects of gender stereotypes on women's reproductive health and sexual health, and propose a method to improve women's health.
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