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The Effects of Poverty on Childhood Brain Development: The Mediating Effect of Caregiving and Stressful Life Events

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TLDR
The finding that exposure to poverty in early childhood materially impacts brain development at school age further underscores the importance of attention to the well-established deleterious effects of poverty on child development.
Abstract
DESIGN, SETTING, AND PARTICIPANTS This study was conducted at an academic research unit at the Washington University School of Medicine in St Louis. Data from a prospective longitudinal study of emotion development in preschool children who participated in neuroimaging at school age were used to investigate the effects of poverty on brain development. Children were assessed annually for 3 to 6 years prior to the time of a magnetic resonance imaging scan, during which they were evaluated on psychosocial, behavioral, and other developmental dimensions. Preschoolers included in the study were 3 to 6 years of age and were recruited from primary care and day care sites in the St Louis metropolitan area; they were annually assessed behaviorally for 5 to 10 years. Healthy preschoolers and those with clinical symptoms of depression participated in neuroimaging at school age/early adolescence.

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Socioeconomic Status in Infancy and the Developing Brain: Functional Connectivity of the Hippocampus and Amygdala

TL;DR: Higher parental education predicted stronger functional connectivity between the left and right hippocampi and the right amygdala with the dorsal anterior cingulate cortex, and between theleft amygdala and bilateral angular gyrus, and in turn, the connectivity of these regions was associated with higher child prosocial behavior.
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A Review of Family Environment and Neurobehavioral Outcomes Following Pediatric Traumatic Brain Injury: Implications of Early Adverse Experiences, Family Stress, and Limbic Development

TL;DR: In this article, a comprehensive review of the more comprehensive literature on family environment and neurobehavioral outcomes in pediatric traumatic brain injury (TBI) and leverage the work in both TBI and non-TBI populations to expand our understanding of the underlying neural mechanisms.
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Timing-specific associations between income-to-needs ratio and hippocampal and amygdala volumes in middle childhood: A preliminary study.

TL;DR: Using a longitudinal birth cohort and linear mixed-effects models, this article identified associations between income-to-needs ratio (INR) at 6 timepoints throughout childhood and hippocampal and amygdala volumes at age 7-9 years (n = 41; 236 INR measurements; 41 brain measurements).
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Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: III. Biology.

TL;DR: In this article , the authors present an overview of pathophysiological mechanisms and neurobiological processes plausibly involved in the effects of major social determinants of health (SDoHs) on clinical outcomes in SSPD.
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A Review of Family Environment and Neurobehavioral Outcomes Following Pediatric Traumatic Brain Injury: Implications of Early Adverse Experiences, Family Stress, and Limbic Development

TL;DR: In this paper , the authors summarize the literature on the family environment's role in neurobehavioral sequelae in children with TBI and explore potential neural correlates by synthesizing the wealth of literature on family environment and limbic development specifically related to the amygdala.
References
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TL;DR: In this paper, the authors present a discussion of whether, if, how, and when a moderate mediator can be used to moderate another variable's effect in a conditional process analysis.
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Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models

TL;DR: An overview of simple and multiple mediation is provided and three approaches that can be used to investigate indirect processes, as well as methods for contrasting two or more mediators within a single model are explored.
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A comparison of methods to test mediation and other intervening variable effects.

TL;DR: A Monte Carlo study compared 14 methods to test the statistical significance of the intervening variable effect and found two methods based on the distribution of the product and 2 difference-in-coefficients methods have the most accurate Type I error rates and greatest statistical power.
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From Neurons to Neighborhoods: The Science of Early Childhood Development

TL;DR: From Neurons to Neighborhoods as discussed by the authors presents the evidence about "brain wiring" and how children learn to learn to speak, think, and regulate their behavior, and examines the effect of the climate-family, child care, community-within which the child grows.
Journal ArticleDOI

Meaningful Differences in the Everyday Experience of Young American Children

TL;DR: Hart and Risley the authors, 1995, the authors ) discuss the effects of gender stereotypes on women's reproductive health and sexual health, and propose a method to improve women's health.
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