The Evolving Landscape of Impella® Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention With Mechanical Circulatory Support
Amit P. Amin,Amit P. Amin,John A. Spertus,Jeptha P. Curtis,Nihar R. Desai,Frederick A. Masoudi,Richard G. Bach,Richard G. Bach,Christian McNeely,Christian McNeely,Firas Al-Badarin,John A. House,Hemant Kulkarni,Sunil V. Rao +13 more
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TLDR
Impella use is rapidly increasing among patients undergoing PCI treated with MCS, with marked variability in its use and associated outcomes, and it was associated with higher rates of adverse events and costs.Abstract:
Background: Impella was approved for mechanical circulatory support (MCS) in 2008, but large-scale, real-world data on its use are lacking. Our objective was to describe trends and variations in Im...read more
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2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
Jean-Philippe Collet,Holger Thiele,Emanuele Barbato,Olivier Barthelemy,Johann Bauersachs,Deepak L. Bhatt,Paul Dendale,Maria Dorobantu,Thor Edvardsen,Thierry Folliguet,Chris P Gale,Martine Gilard,Alexander Jobs,Peter Jüni,Ekaterini Lambrinou,Basil S. Lewis,Julinda Mehilli,Emanuele Meliga,Béla Merkely,Christian Mueller,Marco Roffi,Frans H. Rutten,Dirk Sibbing,George C.M. Siontis +23 more
TL;DR: A correction has been published: European Heart Journal, ehaa895, https://doi.org/10.1093/eurheartj/ehaa-895.
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2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
TL;DR: The guideline for coronary artery revascularization replaces the 2011 coronary artery bypass graft surgery and the 2011 and 2015 percutaneous coronary intervention guidelines, providing a patient-centric approach to guide clinicians in the treatment of patients with significant coronary artery disease undergoing coronary revascularisation as well as the supporting documentation to encourage their use as mentioned in this paper .
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Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock
Sanket S. Dhruva,Sanket S. Dhruva,Joseph S. Ross,Bobak J. Mortazavi,Nathan C. Hurley,Harlan M. Krumholz,Jeptha P. Curtis,Alyssa Berkowitz,Frederick A. Masoudi,John C. Messenger,Craig S. Parzynski,Che Ngufor,Saket Girotra,Amit P. Amin,Nilay Shah,Nihar R. Desai +15 more
TL;DR: Among patients undergoing PCI for AMI complicated by cardiogenic shock from 2015 to 2017, use of an intravascular microaxial LVAD compared with IABP was associated with higher adjusted risk of in-hospital death and major bleeding complications, although study interpretation is limited by the observational design.
Journal ArticleDOI
Left Ventricular Unloading Is Associated With Lower Mortality in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation: Results From an International, Multicenter Cohort Study.
Benedikt Schrage,Peter Moritz Becher,Alexander M. Bernhardt,Hiram G. Bezerra,Stefan Blankenberg,Stefan Brunner,Pascal Colson,Gaston A Cudemus Deseda,Salim Dabboura,Dennis Eckner,Matthias Eden,Ingo Eitel,Derk Frank,Norbert Frey,Masaki Funamoto,Alina Goßling,Tobias Graf,Christian Hagl,Paulus Kirchhof,Danny Kupka,Ulf Landmesser,Jerry Lipinski,Mathew S Lopes,Nicolas Majunke,Octavian Maniuc,Daniel Mcgrath,Sven Möbius-Winkler,David A. Morrow,Marc Mourad,Curt Noel,Peter Nordbeck,Martin Orban,Federico Pappalardo,Federico Pappalardo,Sandeep M. Patel,Matthias Pauschinger,Vittorio Pazzanese,Hermann Reichenspurner,Marcus Sandri,P. Christian Schulze,Robert H. G. Schwinger,Jan Malte Sinning,Adem Aksoy,Carsten Skurk,Lukasz Szczanowicz,Holger Thiele,Franziska Tietz,Anubodh S. Varshney,Lukas Wechsler,Dirk Westermann +49 more
Abstract: Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. The Impella unloads the le...
Journal ArticleDOI
Epidemiology, pathophysiology and contemporary management of cardiogenic shock - a position statement from the Heart Failure Association of the European Society of Cardiology
Ovidiu Chioncel,John Parissis,Alexandre Mebazaa,Holger Thiele,Steffen Desch,Johann Bauersachs,Veli-Pekka Harjola,Elena-Laura Antohi,Mattia Arrigo,Tuvia Ben Gal,Tuvia Ben Gal,Jelena Celutkiene,Sean P. Collins,Daniel DeBacker,Vlad Anton Iliescu,Ewa A. Jankowska,Tiny Jaarsma,Tiny Jaarsma,Kalliopi Keramida,Mitja Lainscak,Lars H. Lund,Lars H. Lund,Alexander R. Lyon,Josep Masip,Josep Masip,Marco Metra,Òscar Miró,Andrea Mortara,Christian Mueller,Wilfried Mullens,Maria Nikolaou,Massimo F Piepoli,Susana Price,Giuseppe M.C. Rosano,Antoine Vieillard-Baron,Jean Mark Weinstein,Stefan D. Anker,Gerasimos Filippatos,Gerasimos Filippatos,Frank Ruschitzka,Andrew J.S. Coats,Petar M. Seferovic,Petar M. Seferovic +42 more
TL;DR: The goal of this review is to summarize the current knowledge concerning the definition, epidemiology, underlying causes, pathophysiology and management of CS based on important lessons from clinical trials and registries, with a focus on improving in‐hospital management.
References
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Multilevel analysis : an introduction to basic and advanced multilevel modeling
Tom A. B. Snijders,Roel Bosker +1 more
TL;DR: In this paper, the authors proposed a multilevel regression model to estimate within-and between-group correlations using a combination of within-group correlation and cross-group evidence.
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A Randomized Clinical Trial to Evaluate the Safety and Efficacy of a Percutaneous Left Ventricular Assist Device Versus Intra-Aortic Balloon Pumping for Treatment of Cardiogenic Shock Caused by Myocardial Infarction
Melchior Seyfarth,Dirk Sibbing,Iris Bauer,Georg M. Fröhlich,Lorenz Bott-Flügel,Robert A. Byrne,Josef Dirschinger,Adnan Kastrati,Albert Schömig +8 more
TL;DR: In patients presenting with cardiogenic shock caused by AMI, the use of a percutaneously placed LVAD (Impella LP 2.5) is feasible and safe, and provides superior hemodynamic support compared with standard treatment using an intra-aortic balloon pump.
Journal ArticleDOI
Appropriate Assessment of Neighborhood Effects on Individual Health: Integrating Random and Fixed Effects in Multilevel Logistic Regression
TL;DR: The authors suggest a measure of heterogeneity, the median odds ratio, that quantifies cluster heterogeneity and facilitates a direct comparison between covariate effects and the magnitude of heterogeneity in terms of well-known odds ratios.
Journal ArticleDOI
Assessing Validity of ICD-9-CM and ICD-10 Administrative Data in Recording Clinical Conditions in a Unique Dually Coded Database
Hude Quan,Bing Li,L. Duncan Saunders,Gerry A Parsons,Carolyn Nilsson,Arif Alibhai,William A. Ghali +6 more
TL;DR: The validity of the International Classification of Disease, 10th Version (ICD-10) administrative hospital discharge data was generally similar though validity differed between coding versions for some conditions.
Journal ArticleDOI
A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump in patients undergoing high-risk percutaneous coronary intervention: the PROTECT II study.
William W. O'Neill,Neal S. Kleiman,Jeffrey W. Moses,José P.S. Henriques,Simon R. Dixon,Joseph M. Massaro,Igor F. Palacios,Brijeshwar Maini,Suresh Mulukutla,Vladimír Džavík,Jeffrey J. Popma,Pamela S. Douglas,Magnus Ohman +12 more
TL;DR: In this paper, the authors compared intra-aortic balloon pump (IABP) and Impella 2.5 for percutaneous coronary intervention in patients with complex multivessel, or left main disease.