Journal ArticleDOI
The nucleolus: A structural and functional interpretation
Franz Wachtler,André Stahl +1 more
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TLDR
This review addresses the problem of understanding nucleolar morphology in terms of nucleolar function by reviewing in situ-cytochemical results that have not led to a generally accepted view on the structure-function correlation for nucleoli.About:
This article is published in Micron.The article was published on 1993-01-01. It has received 138 citations till now. The article focuses on the topics: Nucleolus.read more
Citations
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Journal ArticleDOI
Coexisting Liquid Phases Underlie Nucleolar Subcompartments
Marina Feric,Nilesh Vaidya,Tyler S. Harmon,Diana M. Mitrea,Lian Zhu,Tiffany M. Richardson,Richard W. Kriwacki,Rohit V. Pappu,Clifford P. Brangwynne +8 more
TL;DR: It is shown that subcompartments within the nucleolus represent distinct, coexisting liquid phases that may facilitate sequential RNA processing reactions in a variety of RNP bodies, and suggested that phase separation can give rise to multilayered liquids.
Journal ArticleDOI
Oocyte growth, capacitation and final maturation in cattle
TL;DR: The final oocyte maturation up to metaphase II after LH stimulation of the ovulatory follicle is the culmination of the previous processes and equips the oocyte with a haploid chromosomal compartment and the cell biological apparatus specialized for fertilization and initial embryonic development.
Journal ArticleDOI
The nucleolus and transcription of ribosomal genes.
TL;DR: The recent results on the regulation of rRNA synthesis in relation to the functional organization of the nucleolus are discussed, and an emphasis on the situation encountered in mammalian somatic cells is put on.
Journal ArticleDOI
Proteome analysis of human metaphase chromosomes
Susumu Uchiyama,Shouhei Kobayashi,Hideaki Takata,Takeshi Ishihara,Naoto Hori,Tsunehito Higashi,Kayoko Hayashihara,Takefumi Sone,Daisuke Higo,Takashi Nirasawa,Toshifumi Takao,Sachihiro Matsunaga,Kiichi Fukui +12 more
TL;DR: A four-layer model of metaphase chromosomes is presented, which represents the first compositional view of human metaphase chromosome and provides a protein framework for future research on this topic.
Journal ArticleDOI
Codling moth cytogenetics: karyotype, chromosomal location of rDNA, and molecular differentiation of sex chromosomes.
TL;DR: The demonstrated ways of W chromosome identification will facilitate the development of genetic sexing strains desirable for pest control using the sterile insect technique.
References
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Journal Article
Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes.
TL;DR: The studies suggest that the mitogenic action of PHA does not involve mitosis per se but rather the stage preceding mitosis—the alteration of circulating monocytes and large lymphocytes to a state wherein they are capable of division.
Journal ArticleDOI
Major nucleolar proteins shuttle between nucleus and cytoplasm
TL;DR: These unexpected results suggest a role for these major nucleolar proteins in the nucleocytoplasmic transport of ribosomal components and suggest that transient exposure of shuttling proteins to the cy toplasm may provide a mechanism for cytop lasmic regulation of nuclear activities.
Journal ArticleDOI
Visualization of nucleolar organizer regions im mammalian chromosomes using silver staining
TL;DR: The available cytochemical data suggest that the Ag-AS reaction stains chromosomal proteins at the NOR rather than the rDNA itself, and this was critically demonstrated by Ag- AS staining of the nucleolus organizer regions in karyotypes of the same species and cell lines used for locating the ribosomal cistrons by DNA/RNA in situ hybridization.
Journal ArticleDOI
Visualization of Nucleolar Genes
O. L. Miller,Barbara R. Beatty +1 more
TL;DR: The presence of extrachromosomal nucleoli in amphibian oocytes has permitted isolation and electron microscopic observation of the genes coding for ribosomal RNA precursor molecules.
Journal ArticleDOI
Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form.
N.H. Waseem,David P. Lane +1 more
TL;DR: Results suggest that the PCNA protein may fulfil several separate roles in the cell nucleus associated with changes in its antigenic structure, including leading and lagging strand synthesis at the replication fork.
Related Papers (5)
Fibrillarin: a new protein of the nucleolus identified by autoimmune sera.
Controlled silver-staining of nucleolus organizer regions with a protective colloidal developer: a 1-step method.
W. M. Howell,Deborah Black +1 more