The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.
TLDR
The amino acid sequence of the protein as determined from the nucleotide sequence disagrees with the published alcohol dehydrogenase isozyme I (ADH-I) sequence for 5 of the 347 amino acid residues.About:
This article is published in Journal of Biological Chemistry.The article was published on 1982-03-25 and is currently open access. It has received 491 citations till now. The article focuses on the topics: Consensus sequence & Nucleic acid sequence.read more
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Transcription termination and 3' processing: the end is in site!
TL;DR: In this article, it was shown that 3' cleavage of pre-mRNA in eukaryotes is, in many ways, the phenotypic equivalent of transcription termi-nation.
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Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.
TL;DR: The Shine-Dalgarno sequence, appropriately positioned upstream from an exposed initiator codon, is sufficient to define a bacterial ribosome bnding site?
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Prediction of the Occurrence of the ADP-binding βαβ-fold in Proteins, Using an Amino Acid Sequence Fingerprint
TL;DR: An amino acid sequence “fingerprint” has been derived that can be used to test if a particular sequence will fold into aβαβ-unit with ADP-binding properties, which is in fact a set of 11 rules describing the type of amino acid that should occur at a specific position in a peptide fragment.
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Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
TL;DR: Recent findings suggest that the association of cleavage/polyadenylation factors with the transcriptional complex via the carboxyl-terminal domain of the RNA polymerase II (Pol II) large subunit is the means by which the cell restricts polyadenylations to Pol II transcripts.
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Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes
TL;DR: Codon usage in the highly expressed group shows a higher correlation with tRNA abundance, a greater degree of third base pyrimidine bias, and a lesser tendency to the A+T richness which is characteristic of the yeast genome.
References
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A new method for sequencing DNA
Allan M. Maxam,Walter Gilbert +1 more
TL;DR: Reactions that cleave DNA preferentially at guanines, at adenines,At cytosines and thymines equally, and at cytosine alone are described.
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Codon selection in yeast.
TL;DR: Extreme codon bias is seen for the Saccharomyces cerevisiae genes for the fermentative alcohol dehydrogenase isozyme I (ADH-I) and glyceraldehyde-3-phosphate dehydrogenased genes and a similar phenomenon is observed in the codon preferences of highly expressed genes in Escherichia coli.
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A simple method for DNA restriction site mapping
TL;DR: When a DNA molecule, enzymatically labelled with 32p at one end, is partially digested with a restriction enzyme labelled tdna fragments are obtained which form an overlapping series of molecules, all with a common labelled terminus, a restriction map can be constructed from an analysis of the size distribution of these molecules.
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The ovalbumin gene - sequence of putative control regions
TL;DR: The sequence of regions of the chicken ovalbumin gene believed to be important in the control of initiation of transcription, splicing, and transcription termination or polyadenylation are presented.
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How do eucaryotic ribosomes select initiation regions in messenger RNA
TL;DR: Assessment of present knowledge about the mechanism by which eucar- yotic ribosomes select the correct site for initiation of protein synthesis finds certain features of translational initia- tion in eucaryotes are sufficiently compelling to warrant discussion.