Journal ArticleDOI
The simple β-carboline alkaloids
James R.F. Allen,Bo Holmstedt +1 more
TLDR
The simple β-carbolines are presented as a distinct group of alkaloids displaying structural modification of three basic ring systems and aspects of their metabolism, pharmacological properties and taxonomic significance are briefly summarized.About:
This article is published in Phytochemistry.The article was published on 1980-01-01. It has received 253 citations till now.read more
Citations
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Journal ArticleDOI
HR-MALDI-MS Imaging Assisted Screening of β-Carboline Alkaloids Discovered from Mycena metata
TL;DR: In this paper, a new β-carboline alkaloid, 6-hydroxymetatacarboline D (1d), was isolated from fruiting bodies of M. metata.
Journal ArticleDOI
β-Carbolin-Alkaloide, I. Synthese von 1-Aryl- und 1-Alkenyl-β-carbolinen durch Palladium-katalysierte Kupplungsreaktionen
Franz Bracher,Dirk Hildebrand +1 more
TL;DR: In this paper, the synthesis of 1-Aryl and 1-Alkenyl-β-carbolines by Palladium-catalyzed coupling reactions of 6 with aryl boronic acids is described.
Journal ArticleDOI
Visible-light photoredox catalysis: direct synthesis of fused β-carbolines through an oxidation/[3 + 2] cycloaddition/oxidative aromatization reaction cascade in batch and flow microreactors
D. Chandrasekhar,Satheesh Borra,Jeevak Sopanrao Kapure,Ghule Shailendra Shivaji,G. Srinivasulu,Ram Awatar Maurya,Ram Awatar Maurya +6 more
TL;DR: Several structurally diverse heterocyclic scaffolds were obtained in good yields by coupling of tetrahydro-β-carbolines with a variety of dipolarophiles under photoredox multiple C–C bond forming events.
BookDOI
Neurotoxic Factors in Parkinson’s Disease and Related Disorders
TL;DR: This work presents a meta-analysis of catecholamine-Oxidation Pathways in Neurotoxicity, pesticides and metals in Nigrostriatal Degeneration, and Mechanisms of Neuroprotection.
Journal ArticleDOI
A multidisciplinary overview of intoxicating enema rituals in the western hemisphere.
TL;DR: The literature yields convincing clinical evidence that atropine, cocaine, nicotine and scopolamine are effective following nasal application, but experimental confirmation of the efficacy of nasal tryptamine alkaloids is still awaited.
References
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Studies with reversible inhibitors of monoamine oxidase: Harmaline and related compounds
TL;DR: Harmaline and related compounds have been shown to be potent inhibitors of monoamine oxidase effecting 50 per cent inhibition of serotonin metabolism at 10−6 M.
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Smoke composition. An extensive investigation of the water-soluble portion of cigarette smoke
Journal ArticleDOI
“Ayahuasca,” the South American hallucinogenic drink: An ethnobotanical and chemical investigation
L. Rivier,Jan-Erik Lindgren +1 more
TL;DR: Harmine, Harmaline, Tetrahydroharmine and Dimethyltryptamine have been found in the Ayahuasca drink.
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The isolation of harmane and norharmane from tobacco and cigarette smoke
E.H. Poindexter,R.D. Carpenter +1 more
TL;DR: Harmane and norharmane were isolated from cured tobacco and its smoke and the addition of radioactive tryptophan to the tobacco resulted in the isolation of radioactive harmane alkaloids in the smoke, establishing the presence of indole alkaloid in tobacco.
Journal ArticleDOI
Interactions of norharman and harman with DNA
TL;DR: Agarose gel electrophoresis of circular DNA, closed in the presence or absence of norharman revealed that the dye intercalates DNA, thereby causing 17 +/- 3 degrees unwinding of the double helix.