Journal ArticleDOI
The simple β-carboline alkaloids
James R.F. Allen,Bo Holmstedt +1 more
TLDR
The simple β-carbolines are presented as a distinct group of alkaloids displaying structural modification of three basic ring systems and aspects of their metabolism, pharmacological properties and taxonomic significance are briefly summarized.About:
This article is published in Phytochemistry.The article was published on 1980-01-01. It has received 253 citations till now.read more
Citations
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Journal ArticleDOI
Partition Coefficients of Indoles and Betacarbolines
TL;DR: The results show that the HBD properties are similar for indoles and betacarbolines, and the HBA capacity, as expected, is significantly enhanced by the contribution of the extra pyridinic or piperidinic ring in betaccarbolines.
Journal ArticleDOI
Biphasic effects of acetaldehyde‐biogenic amine condensation products on membrane fluidity
TL;DR: The effects of four acetaldehyde‐biogenic amine condensation products on membrane fluidity of liposomes, consisting of 1‐palmitoyl‐2‐oleoylphosphatidylcholine and cholesterol, are studied by measuring fluorescence polarization using different probes.
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Determination of tetrahydro-β-carbolines in urine by high-performance liquid chromatography with suppression of artefact formation
TL;DR: The proposed method enables the determination of the genuine urinary concentrations of TBC and MTBC without involving their artefacts.
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Identification of potential human urinary biomarkers for tomato juice intake by mass spectrometry-based metabolomics
TL;DR: Steroidal glycoalkaloids in tomato juice are cleaved after ingestion, and hydroxylated and sulfonated metabolites of their aglycones might serve as urinary biomarkers for tomato juice intake.
Journal ArticleDOI
The psychoactive flora of Papua New Guinea.
TL;DR: It is recommended that more systematic and multidisciplinary research is required on the psychoactive flora of Papua New Guinea, which has the potential for the discovery and understanding of new psychoactive drugs.
References
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Journal ArticleDOI
Studies with reversible inhibitors of monoamine oxidase: Harmaline and related compounds
TL;DR: Harmaline and related compounds have been shown to be potent inhibitors of monoamine oxidase effecting 50 per cent inhibition of serotonin metabolism at 10−6 M.
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Smoke composition. An extensive investigation of the water-soluble portion of cigarette smoke
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“Ayahuasca,” the South American hallucinogenic drink: An ethnobotanical and chemical investigation
L. Rivier,Jan-Erik Lindgren +1 more
TL;DR: Harmine, Harmaline, Tetrahydroharmine and Dimethyltryptamine have been found in the Ayahuasca drink.
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The isolation of harmane and norharmane from tobacco and cigarette smoke
E.H. Poindexter,R.D. Carpenter +1 more
TL;DR: Harmane and norharmane were isolated from cured tobacco and its smoke and the addition of radioactive tryptophan to the tobacco resulted in the isolation of radioactive harmane alkaloids in the smoke, establishing the presence of indole alkaloid in tobacco.
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Interactions of norharman and harman with DNA
TL;DR: Agarose gel electrophoresis of circular DNA, closed in the presence or absence of norharman revealed that the dye intercalates DNA, thereby causing 17 +/- 3 degrees unwinding of the double helix.