Journal ArticleDOI
The simple β-carboline alkaloids
James R.F. Allen,Bo Holmstedt +1 more
TLDR
The simple β-carbolines are presented as a distinct group of alkaloids displaying structural modification of three basic ring systems and aspects of their metabolism, pharmacological properties and taxonomic significance are briefly summarized.About:
This article is published in Phytochemistry.The article was published on 1980-01-01. It has received 253 citations till now.read more
Citations
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Monoamine oxidase inhibitors in South American hallucinogenic plants: tryptamine and beta-carboline constituents of ayahuasca.
TL;DR: The levels of DMT and beta-carbolines found in the ayahuasca samples examined in the present study were an order of magnitude greater than the levels reported in a previous study, which indicated that their effects in combination are additive, rather than synergistic or antagonistic.
Journal ArticleDOI
Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges.
TL;DR: Ayahuasca is a hallucinogenic beverage that is prominent in the ethnomedicine and shamanism of indigenous Amazonian tribes as discussed by the authors and is used as a sacrament by several syncretic churches.
Journal ArticleDOI
Photoredox activation and anion binding catalysis in the dual catalytic enantioselective synthesis of β-amino esters
Giulia Bergonzini,Corinna S. Schindler,Carl-Johan Wallentin,Eric N. Jacobsen,Corey R. J. Stephenson +4 more
TL;DR: The enantioselective oxidative C-H functionalization of tetrahydroisoquinoline derivatives is achieved through the merger of photoredox and asymmetric anion-binding catalysis and introduces a potentially general approach to asymmetric transformations in oxidative photocatalysis.
Journal ArticleDOI
Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth.
Rainer-B. Volk,Franz H. Furkert +1 more
TL;DR: The antimicrobial activity of two cyanobacterial exometabolites, norharmane (9H-pyrido(3,4-b)indole) and 4,4'-dihydroxybiphenyl, was determined in suspension assays and the natural function as allelopathic chemicals and a possible applicability as antifouling agents or leads for the development of new antIFouling chemicals are discussed.
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Exposure to beta-carbolines norharman and harman.
W. Pfau,Kerstin Skog +1 more
TL;DR: The literature data on levels of norharman and harman in fried meat and fish, meat extracts, alcoholic drinks, and coffee brews is summarized to indicate that inhalative exposure leads to a rapid increase in plasma levels and high bioavailability of norHarman and Harman and there are indications that sublingual absorption may increase dietary uptake of beta-carbolines.
References
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Alkaloidal constituents ofpeganum harmala and synthesis of the minor alkaloid deoxyvascinone
Asima Chatterjee,M. Ganguly +1 more
TL;DR: In this paper, a new synthesis of deoxyvascinone has been achieved from anthranilic acid and γ-aminobutyric acid, for which a plausible structure has been postulated from spectral evidences.
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Ueber Anhalonium Lewinii
Journal ArticleDOI
The biosynthesis and metabolism of harman in passiflora edulis—I
M. Slaytor,I.J. McFarlane +1 more
TL;DR: The β-carboline alkaloid harman was shown by a combination of feeding and trapping experiments to be formed in Passiflora edulis from N-acetyltryptamine via harmalan.