Three-Dimensional Printing of Hydroxyapatite Composites for Biomedical Application
Yanting Han,Qianqian Wei,Pengbo Chang,Kehui Hu,Oseweuba Valentine Okoro,Amin Shavandi,Lei Nie +6 more
- Vol. 11, Iss: 4, pp 353
TLDR
Three-dimensional printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds and the desired properties via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored.Abstract:
Hydroxyapatite (HA) and HA-based nanocomposites have been recognized as ideal biomaterials in hard tissue engineering because of their compositional similarity to bioapatite However, the traditional HA-based nanocomposites fabrication techniques still limit the utilization of HA in bone, cartilage, dental, applications, and other fields In recent years, three-dimensional (3D) printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds This review therefore explores available 3D printing technologies for the preparation of porous HA-based nanocomposites In the present review, different 3D printed HA-based scaffolds composited with natural polymers and/or synthetic polymers are discussed Furthermore, the desired properties of HA-based composites via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored Lastly, the applications and the next generation of HA-based nanocomposites for tissue engineering are discussedread more
Citations
More filters
A Novel Fabrication Method of Macroporous Biodegradable Polymer Scaffolds Using Gas Foaming Salt as Porogen Additive
TL;DR: The novelty of this new method is that the PLLA paste containing ammonium bicarbonate salt particles can be easily handled and molded into any shape, allowing for fabricating a wide range of temporal tissue scaffolds requiring a specific shape and geometry.
Journal ArticleDOI
Natural Hydrogel-Based Bio-Inks for 3D Bioprinting in Tissue Engineering: A Review
TL;DR: In this article , the state of the art of the utilization of bio-inks based on natural polymers (biopolymers), such as cellulose, agarose, alginate, decellularized matrix, in 3D bioprinting is explored.
Journal ArticleDOI
Injectable nanocomposite hydrogels as an emerging platform for biomedical applications: A review.
TL;DR: This work aims to critically review injectable nanocomposite hydrogels, their preparation methods, properties, functionalities, and versatile biomedical and pharmaceutical applications such as tissue engineering, drug delivery, and cancer labeling and therapy.
Journal ArticleDOI
Protein-Based 3D Biofabrication of Biomaterials.
TL;DR: The protein gelation process is the unfolding of its native structure and aggregation into a gel network, which is then stabilized through both noncovalent and covalent cross-link.
Journal ArticleDOI
Biodegradable and Biocompatible 3D Constructs for Dental Applications: Manufacturing Options and Perspectives
TL;DR: In this article, the authors report the currently employed manufacturing processes for the development of engineered self-supporting, easily processable, and cost-effective 3D constructs with target-specific tuneable mechanics, bioactivity, and degradability aspects in the oral cavity for their potential use in numerous dental applications ranging from soft pulp tissues to hard alveolar bone tissues.
References
More filters
Journal ArticleDOI
Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
Journal ArticleDOI
Biodegradable polymers as biomaterials
TL;DR: This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications ofBiodegradable synthetic and natural polymers.
Journal ArticleDOI
Porous scaffold design for tissue engineering
TL;DR: The integration of CTD with SFF to build designer tissue-engineering scaffolds is reviewed and the mechanical properties and tissue regeneration achieved using designer scaffolds are details.
Journal ArticleDOI
Collagen Structure and Stability
TL;DR: The fibrillar structure of type I collagen-the prototypical collagen fibril-has been revealed in detail and will guide further development of artificial collagenous materials for biomedicine and nanotechnology.
Journal ArticleDOI
Chitosan—A versatile semi-synthetic polymer in biomedical applications
TL;DR: The chemical structure and relevant biological properties of chitosan for regenerative medicine have been summarized as well as the methods for the preparation of controlled drug release devices and their applications.