Journal ArticleDOI
Treadmill exercise reduces self-administration of morphine in male rats.
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TLDR
As exercise can activate many neurotransmitter systems involved in the addiction process and increase the release of endorphins, it is likely that the effect of short-term and mid-term exercises on the self-administration of morphine in rats will decrease.About:
This article is published in Pathophysiology.The article was published on 2009-06-01. It has received 75 citations till now. The article focuses on the topics: Endorphins.read more
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Natural rewards, neuroplasticity, and non-drug addictions.
TL;DR: Exposure to non-drug rewards can alter neural plasticity in regions of the brain that are affected by drugs of abuse, and repeated exposure to natural rewards might induce neuroplasticity that either promotes or counteracts addictive behavior.
Journal ArticleDOI
Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis.
TL;DR: Clinical and preclinical evidence for the efficacy of exercise at different phases of the addiction process and potential neurobiological mechanisms are discussed focusing on interactions with dopaminergic and glutamatergic signaling and chromatin remodeling in the reward pathway.
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Exercise as a potential treatment for drug abuse: evidence from preclinical studies.
Mark A. Smith,Wendy J. Lynch +1 more
TL;DR: Collectively, these studies have provided convincing evidence to support the development of exercise-based interventions to reduce compulsive patterns of drug intake in clinical and at-risk populations.
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Neurobiology of hyperactivity and reward: agreeable restlessness in anorexia nervosa.
TL;DR: This work focuses on the neurobiological basis of hyperactivity and reward in both animals and humans suggesting that the mesolimbic dopamine and hypothalamic orexin neurons play central roles.
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Voluntary exercise ameliorates cognitive deficits in morphine dependent rats: the role of hippocampal brain-derived neurotrophic factor.
Hossein Miladi-Gorji,Ali Rashidy-Pour,Yaghoub Fathollahi,Maziar Mohammad Akhavan,Saeed Semnanian,Manouchehr Safari +5 more
TL;DR: It is demonstrated that voluntary exercise ameliorates, via a TrkB-mediated mechanism, the cognitive deficits that are induced by chronic morphine.
References
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Journal ArticleDOI
Ageing, fitness and neurocognitive function.
Arthur F. Kramer,Sowon Hahn,Neal J. Cohen,Marie T. Banich,Edward McAuley,Catherine R. Harrison,Julie Chason,Eli Vakil,Lynn Bardell,Richard A. Boileau,Angela Colcombe +10 more
TL;DR: It is found that those who received aerobic training showed substantial improvements in performance on tasks requiring executive control compared with anaerobically trained subjects.
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Cellular and synaptic adaptations mediating opioid dependence.
TL;DR: A review on the adaptive changes in cellular and synaptic function induced by chronic morphine treatment can be found in this article, where the initial steps of opioid action are mediated through the activation of G protein-linked receptors.
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The neurotrophin hypothesis for synaptic plasticity.
TL;DR: The characteristics of synaptic changes that are induced by neurotrophins suggest that this family of proteins is crucial for providing a molecular background in which activity-dependent plasticity can occur at selective synaptic sites within the neural network.
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High, usual and impaired functioning in community-dwelling older men and women: Findings from the MacArthur Foundation Research Network on successful aging
Lisa F. Berkman,Teresa E. Seeman,Marilyn S. Albert,Dan G. Blazer,Robert L. Kahn,Richard C. Mohs,Caleb E. Finch,Edward L. Schneider,Carl W. Cotman,Gerald E. McClearn,John R. Nesselroade,David L. Featherman,Norman Garmezy,Guy M. McKhann,Gilbert Brim,Denis Prager,John W. Rowe +16 more
TL;DR: The range of complex physical and cognitive abilities of older men and women functioning at high, medium and impaired ranges is determined and the psychosocial and physiological conditions that discriminate those in the high functioning group from those functioning at middle or impaired ranges are determined.
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Exercise and Brain Neurotransmission
Romain Meeusen,K. De Meirleir +1 more
TL;DR: The results of the first studies using microdialysis and voltammetry indicate that the release of most neurotransmitters is influenced by exercise, which indicates that a further understanding of the effects of exercise on brain neurotransmission can be gained.