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Allon Wagner
Researcher at University of California, Berkeley
Publications - 38
Citations - 3741
Allon Wagner is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Metabolic network & Transcriptome. The author has an hindex of 14, co-authored 34 publications receiving 2885 citations. Previous affiliations of Allon Wagner include University of California & Tel Aviv University.
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Journal ArticleDOI
The Human Cell Atlas
Aviv Regev,Aviv Regev,Aviv Regev,Sarah A. Teichmann,Sarah A. Teichmann,Sarah A. Teichmann,Eric S. Lander,Eric S. Lander,Eric S. Lander,Ido Amit,Christophe Benoist,Ewan Birney,Bernd Bodenmiller,Bernd Bodenmiller,Peter J. Campbell,Peter J. Campbell,Piero Carninci,Menna R. Clatworthy,Hans Clevers,Bart Deplancke,Ian Dunham,James Eberwine,Roland Eils,Roland Eils,Wolfgang Enard,Andrew Farmer,Lars Fugger,Berthold Göttgens,Nir Hacohen,Nir Hacohen,Muzlifah Haniffa,Martin Hemberg,Seung K. Kim,Paul Klenerman,Paul Klenerman,Arnold R. Kriegstein,Ed S. Lein,Sten Linnarsson,Emma Lundberg,Emma Lundberg,Joakim Lundeberg,Partha P. Majumder,John C. Marioni,John C. Marioni,John C. Marioni,Miriam Merad,Musa M. Mhlanga,Martijn C. Nawijn,Mihai G. Netea,Garry P. Nolan,Dana Pe'er,Anthony Phillipakis,Chris P. Ponting,Stephen R. Quake,Wolf Reik,Wolf Reik,Wolf Reik,Orit Rozenblatt-Rosen,Joshua R. Sanes,Rahul Satija,Ton N. Schumacher,Alex K. Shalek,Alex K. Shalek,Alex K. Shalek,Ehud Shapiro,Padmanee Sharma,Jay W. Shin,Oliver Stegle,Michael R. Stratton,Michael J. T. Stubbington,Fabian J. Theis,Matthias Uhlen,Matthias Uhlen,Alexander van Oudenaarden,Allon Wagner,Fiona M. Watt,Jonathan S. Weissman,Barbara J. Wold,Ramnik J. Xavier,Nir Yosef,Nir Yosef,Human Cell Atlas Meeting Participants +81 more
TL;DR: An open comprehensive reference map of the molecular state of cells in healthy human tissues would propel the systematic study of physiological states, developmental trajectories, regulatory circuitry and interactions of cells, and also provide a framework for understanding cellular dysregulation in human disease.
Journal ArticleDOI
Revealing the vectors of cellular identity with single-cell genomics
TL;DR: In this paper, a cell is represented as a superposition of "basis vectors", each determining a different (but possibly dependent) aspect of cellular organization and function, which can be used for constructing and characterizing a reference map of cell identities.
Journal ArticleDOI
Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma
Saverio Tardito,Anais Oudin,Shafiq U. Ahmed,Fred Fack,Olivier Keunen,Liang Zheng,Hrvoje Miletic,Per Øystein Sakariassen,Adam Weinstock,Allon Wagner,Susan L. Lindsay,Andreas K. Hock,Susan C. Barnett,Eytan Ruppin,Svein H. Mørkve,Morten Lund-Johansen,Morten Lund-Johansen,Anthony J. Chalmers,Rolf Bjerkvig,Simone P. Niclou,Eyal Gottlieb +20 more
TL;DR: It is shown here that in glioblastoma (GBM) cells, almost half of the Gln-derived glutamate (Glu) is secreted and does not enter the TCA cycle, and that inhibiting glutaminolysis does not affect cell proliferation.
Revealing the vectors of cellular identity with single-cell genomics
TL;DR: Single-cell genomics has now made it possible to create a comprehensive atlas of human cells and has reopened definitions of a cell's identity and of the ways in which identity is regulated by the cell's molecular circuitry.
Journal ArticleDOI
Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution
Russell B. Fletcher,Diya Das,Levi Gadye,Kelly Street,Ariane Baudhuin,Allon Wagner,Michael B. Cole,Quetzal Flores,Yoon Gi Choi,Nir Yosef,Elizabeth Purdom,Sandrine Dudoit,Davide Risso,John Ngai,John Ngai +14 more
TL;DR: It is demonstrated that Wnt signaling regulates stem cell fate by promoting neuronal fate choices, and provides a model for deconstructing similar hierarchies in other stem cell niches.