Andrew Barron

TL;DR: Comparisons of the cytoskeleton and endocytic trafficking systems of Trypanosoma brucei with those of humans and other eukaryotic organisms reveal major differences.

TL;DR: The crucial role that accessory elements play in the rapid evolution of S. aureus is clearly illustrated by comparing the MSSA476 genome with that of an extremely closely related MRSA community-acquired strain; the differential distribution of large mobile elements carrying virulence and drug-resistance determinants may be responsible for the clinically important phenotypic differences in these strains.

TL;DR: The genome sequence revealed key information about the phylogeny of C. rodentium and suggested that C. rodentsium and EPEC/EHEC have converged on a common host infection strategy through access to a common pool of mobile DNA and that C rodentium has lost gene functions associated with a previous pathogenic niche.

TL;DR: Functional and bioinformatic analysis suggests that SPI-7 has a mosaic structure and may have evolved as a consequence of several independent insertion events, and that it may be a mobile element, such as a conjugative transposon or an integrated plasmid remnant.

TL;DR: The results suggest that North American isolates of Pa have acquired virulence against man via the acquisition of a plasmid and specific virulence factors with similarity to those shown to play roles in pathogenicity against humans in other bacteria.