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Andrew K. MacLeod
Researcher at University of Edinburgh
Publications - 11
Citations - 1814
Andrew K. MacLeod is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Population & Galaxy cluster. The author has an hindex of 8, co-authored 11 publications receiving 1585 citations. Previous affiliations of Andrew K. MacLeod include The Roslin Institute & Western General Hospital.
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Journal ArticleDOI
Runs of Homozygosity in European Populations
Ruth McQuillan,Anne-Louise Leutenegger,Rehab Abdel-Rahman,Rehab Abdel-Rahman,Christopher S. Franklin,Marijana Peričić,Lovorka Barac-Lauc,Nina Smolej-Narančić,Branka Janićijević,Ozren Polasek,Ozren Polasek,Albert Tenesa,Andrew K. MacLeod,Susan M. Farrington,Pavao Rudan,Caroline Hayward,Veronique Vitart,Igor Rudan,Igor Rudan,Sarah H. Wild,Malcolm G. Dunlop,Alan F. Wright,Harry Campbell,James F. Wilson +23 more
TL;DR: Using pedigrees to identify individuals with no shared maternal and paternal ancestors in five, and probably at least ten, generations, it is shown that ROHs measuring up to 4 Mb are common in demonstrably outbred individuals.
Journal ArticleDOI
Genome-wide association study identifies five loci associated with lung function.
Emmanouela Repapi,Ian Sayers,Louise V. Wain,Paul Burton,Toby Johnson,Ma'en Obeidat,Jing Hua Zhao,Adaikalavan Ramasamy,Guangju Zhai,Veronique Vitart,Jennifer E. Huffman,Wilmar Igl,E Albrecht,Panagiotis Deloukas,John Henderson,Raquel Granell,Wendy L. McArdle,Alicja R. Rudnicka,Inês Barroso,Loos Rjf.,Nicholas J. Wareham,Linda Mustelin,Taina Rantanen,Ida Surakka,Ida Surakka,Medea Imboden,H E Wichmann,Ivica Grković,Stipan Janković,Lina Zgaga,Hartikainen A-L.,Hartikainen A-L.,Hartikainen A-L.,Leena Peltonen,Leena Peltonen,Leena Peltonen,Ulf Gyllensten,Åsa Johansson,Ghazal Zaboli,Harry Campbell,Sarah H. Wild,James F. Wilson,Sven Gläser,Georg Homuth,Henry Völzke,Massimo Mangino,Nicole Soranzo,Nicole Soranzo,Tim D. Spector,Ozren Polasek,Igor Rudan,Igor Rudan,Alan F. Wright,Markku Heliövaara,Samuli Ripatti,Samuli Ripatti,Anneli Pouta,Åsa Torinsson Naluai,Olin A-C.,Kjell Torén,Mark E. Cooper,Alan James,Lyle J. Palmer,Lyle J. Palmer,Aroon D. Hingorani,S.G. Wannamethee,Peter H. Whincup,George Davey Smith,Shah Ebrahim,Tricia M. McKeever,Ian D. Pavord,Andrew K. MacLeod,Andrew D. Morris,David J. Porteous,Cyrus Cooper,Cyrus Cooper,Elaine M. Dennison,Seif O. Shaheen,Stefan Karrasch,E Schnabel,Holger Schulz,H Grallert,Nabila Bouatia-Naji,Jérôme Delplanque,Philippe Froguel,Philippe Froguel,John D Blakey,John Britton,Richard W Morris,John W. Holloway,Debbie A Lawlor,Jennie Hui,Jennie Hui,Fredrik Nyberg,Fredrik Nyberg,Jarvelin M-R.,Catherine Jackson,Mika Kähönen,Jaakko Kaprio,Jaakko Kaprio,Nicole Probst-Hensch,Nicole Probst-Hensch,Beate Koch,Caroline Hayward,David M. Evans,Paul Elliott,Paul Elliott,David P. Strachan,Ian P. Hall,Martin D. Tobin +109 more
TL;DR: Genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) in the SpiroMeta consortium offers mechanistic insight into pulmonary function regulation and indicate potential targets for interventions to alleviate respiratory disease.
Journal ArticleDOI
Genetic Copy Number Variation and General Cognitive Ability
Andrew K. MacLeod,Gail Davies,Antony Payton,Albert Tenesa,Sarah E. Harris,David C. Liewald,Xiayi Ke,Michelle Luciano,Lorna M. Lopez,Alan J. Gow,Janie Corley,Paul Redmond,Geraldine McNeill,Andrew Pickles,William E R Ollier,Michael A. Horan,John M. Starr,Neil Pendleton,Pippa A. Thomson,David J. Porteous,Ian J. Deary +20 more
TL;DR: This is the first study to examine the effects of rare CNVs as called by multiple algorithms on cognition in a large non-clinical sample, and finds no effects of such variants on general cognitive ability.
Journal ArticleDOI
On the structure of tidal tails
TL;DR: In this article, the authors examined the longitudinal distribution of the stars escaping from a cluster along tidal tails using both theory and simulations and showed that, even in the case of a star cluster in a circular galactic orbit, when the tide is steady, the distribution exhibits maxima at a distance of many tidal radii from the cluster.
Journal ArticleDOI
On the structure of tidal tails
TL;DR: In this paper, the authors examined the longitudinal distribution of the stars escaping from a cluster along tidal tails using both theory and simulations and showed that, even in the case of a star cluster in a circular galactic orbit, when the tide is steady, the distribution exhibits maxima at a distance of many tidal radii from the cluster.