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Carlos A. Guzmán
Researcher at University of Genoa
Publications - 281
Citations - 10481
Carlos A. Guzmán is an academic researcher from University of Genoa. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 54, co-authored 260 publications receiving 9506 citations. Previous affiliations of Carlos A. Guzmán include Hannover Medical School & Bill & Melinda Gates Foundation.
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Journal ArticleDOI
Hepatitis C Virus Isolates from Argentina Disclose a Novel Genotype 1-Associated Restriction Pattern
María Inés Gismondi,Lothar H. Staendner,Saul Grinstein,Carlos A. Guzmán,María Victoria Preciado +4 more
TL;DR: Hepatitis C virus isolates which disclosed a novel genotype 1-associated restriction pattern by restriction fragment length polymorphism analysis were characterized and revealed that these isolates constitute a novel genetic lineage within the main cluster of genotypes 1 strains.
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Local treatment with BPPcysMPEG reduces allergic airway inflammation in sensitized mice.
S. Knothe,V. Mutschler,Sabine Rochlitzer,Carla Winkler,Thomas Ebensen,Carlos A. Guzmán,Jens M. Hohlfeld,Armin Braun,Meike Müller +8 more
TL;DR: It is concluded that BPPcysMPEG was able to influence the immune system with regard to subsequent allergen contact by TLR2/6 agonization and to reduce allergic airway inflammation by preventive modulation of the innate immune system via TLR 2/ 6 agonization.
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Construction and characterization of genetically-marked bivalent anti-Shigella dysenteriae 1 and anti-Shigella flexneri Y live vaccine candidates.
Silke R. Klee,B D Tzschaschel,Mahavir Dr Singh,Inger C. Fält,Alf A. Lindberg,Kenneth N. Timmis,Carlos A. Guzmán +6 more
TL;DR: The recombinant clones constitute promising vaccine candidates which can readily be distinguished from endemic shigellae by their non-antibiotic resistance marker.
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B cell depletion impairs vaccination-induced CD8 + T cell responses in a type I interferon-dependent manner.
Theresa Graalmann,Katharina Borst,Himanshu Manchanda,Lea A. I. Vaas,Matthias Bruhn,Lukas Graalmann,Mario Köster,Murielle Verboom,Michael Hallensleben,Carlos A. Guzmán,Gerd Sutter,Reinhold E. Schmidt,Torsten Witte,Ulrich Kalinke +13 more
TL;DR: In this paper, the authors studied CD8+ T cell expansion in rituximab-treated rheumatoid arthritis (RA) patients and B cell-deficient mice on vaccination/infection with different vaccines/pathogens.
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Evaluation of invalid vaccine doses in 31 countries of the WHO African Region.
Manas K. Akmatov,Elizabeth Kimani-Murage,Frank Pessler,Carlos A. Guzmán,Gérard Krause,Lothar Kreienbrock,Rafael T. Mikolajczyk +6 more
TL;DR: Timing of childhood vaccinations should be improved to ensure an optimal protection against vaccine-preventable infections and to avoid unnecessary wastage in these economically deprived countries.