C
Christopher A. Haiman
Researcher at University of Southern California
Publications - 783
Citations - 65352
Christopher A. Haiman is an academic researcher from University of Southern California. The author has contributed to research in topics: Breast cancer & Genome-wide association study. The author has an hindex of 106, co-authored 687 publications receiving 54813 citations. Previous affiliations of Christopher A. Haiman include University of California, San Francisco & National Institutes of Health.
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Journal ArticleDOI
The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study
Robert Carreras-Torres,Philip C Haycock,Caroline L Relton,Richard M. Martin,George Davey Smith,Peter Kraft,Chi Gao,Shelley S. Tworoger,Shelley S. Tworoger,Loic Le Marchand,Lynne R. Wilkens,Sungshim L. Park,Christopher A. Haiman,John K. Field,Michael P.A. Davies,Michael W. Marcus,Geoffrey Liu,Neil E. Caporaso,David C. Christiani,Yongyue Wei,Chu Chen,Jennifer A. Doherty,Gianluca Severi,Gary E. Goodman,Rayjean J. Hung,Christopher I. Amos,James D. McKay,Mattias Johansson,Paul Brennan +28 more
TL;DR: The results indicate that higher BMI may increase the risk of certain types of lung cancer, in particular SQ and SC carcinoma.
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Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.
Christopher A. Haiman,Rachel R Garcia,Chris Hsu,Lucy Xia,Helen Ha,Xin Sheng,Loic Le Marchand,Laurence N. Kolonel,Brian E. Henderson,Michael R. Stallcup,Geoffrey L. Greene,Michael F. Press +11 more
TL;DR: Common coding variation in coactivator and corepressor genes do not make a substantial contribution to breast cancer risk in the general population and may serve as a valuable resource for investigations of other hormone-related phenotypes.
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Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk.
Burcu F. Darst,Xin Sheng,Rosalind A. Eeles,Zsofia Kote-Jarai,David V. Conti,Christopher A. Haiman +5 more
TL;DR: In this article, the authors investigated the combined effect of rare and common variants on prostate cancer risk using a polygenic risk score (PRS) and found that the risk conveyed by rare variants could vary depending on an individual's genetic profile of common risk variants.
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Association of Cancer Susceptibility Variants with Risk of Multiple Primary Cancers: the Population Architecture using Genomics and Epidemiology Study
S. Lani Park,Christian Caberto,Yi Lin,Robert Goodloe,Logan Dumitrescu,Shelly Ann Love,Tara C. Matise,Lucia A. Hindorff,Jay H. Fowke,Fredrick R. Schumacher,Jennifer L. Beebe-Dimmer,Chu Chen,Lifang Hou,Fridtjof Thomas,Ewa Deelman,Ying Han,Ulrike Peters,Kari E. North,Gerardo Heiss,Dana C. Crawford,Christopher A. Haiman,Lynne R. Wilkens,William S. Bush,Charles Kooperberg,Iona Cheng,Loic Le Marchand +25 more
TL;DR: This study has identified rs578776 and rs11249433 as risk variants for IMPC and these findings may help to identify genetic regions associated with IMPC.
Journal ArticleDOI
Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium
Nikhil K. Khankari,Harvey J. Murff,Chenjie Zeng,Wanqing Wen,Rosalind A. Eeles,Douglas F. Easton,Zsofia Kote-Jarai,Ali Amin Al Olama,Sara Benlloch,Kenneth Muir,Graham G. Giles,Fredrik Wiklund,Henrik Grönberg,Christopher A. Haiman,Johanna Schleutker,Børge G. Nordestgaard,Ruth C. Travis,Jenny L Donovan,Nora Pashayan,Kay-Tee Khaw,Janet L. Stanford,William J. Blot,Stephen N. Thibodeau,Christiane Maier,Adam S. Kibel,Cezary Cybulski,Lisa A. Cannon-Albright,Hermann Brenner,Jong Hyuk Park,Radka Kaneva,Jyotsna Batra,Manuel R. Teixeira,Hardev Pandha,Wei Zheng +33 more
TL;DR: Results from this study suggest that circulating ω-3 and ψ-6 PUFAs may have a different role in the aetiology of early- and late-onset prostate cancer.