C
Christopher A. Haiman
Researcher at University of Southern California
Publications - 783
Citations - 65352
Christopher A. Haiman is an academic researcher from University of Southern California. The author has contributed to research in topics: Breast cancer & Genome-wide association study. The author has an hindex of 106, co-authored 687 publications receiving 54813 citations. Previous affiliations of Christopher A. Haiman include University of California, San Francisco & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.
Christopher I. Amos,Joe Dennis,Zhaoming Wang,Jinyoung Byun,Fredrick R. Schumacher,Simon A. Gayther,Graham Casey,David J. Hunter,Thomas A. Sellers,Stephen B. Gruber,Alison M. Dunning,Kyriaki Michailidou,Laura Fachal,Kimberly F. Doheny,Amanda B. Spurdle,Yafang Li,Xiangjun Xiao,Jane Romm,Elizabeth W. Pugh,Gerhard A. Coetzee,Dennis J. Hazelett,Stig E. Bojesen,Charlisse Caga-Anan,Christopher A. Haiman,Ahsan Kamal,Craig Luccarini,Daniel C. Tessier,Daniel Vincent,Francois Bacot,David Van Den Berg,Stefanie A. Nelson,Stephen Demetriades,David E. Goldgar,Fergus J. Couch,Judith L. Forman,Graham G. Giles,Graham G. Giles,David V. Conti,Heike Bickeböller,Angela Risch,Angela Risch,Melanie Waldenberger,Irene Brüske-Hohlfeld,Belynda Hicks,Hua Ling,Lesley McGuffog,Lesley McGuffog,Andy C. H. Lee,Karoline Kuchenbaecker,Penny Soucy,Judith Manz,Julie M. Cunningham,Katja Butterbach,Zsofia Kote-Jarai,Peter Kraft,Liesel M. FitzGerald,Liesel M. FitzGerald,Sara Lindström,Sara Lindström,Marcia Adams,James McKay,Catherine M. Phelan,Sara Benlloch,Linda E. Kelemen,Paul Brennan,Marjorie J. Riggan,Tracy A. O'Mara,Hongbing Shen,Yongyong Shi,Deborah J. Thompson,Marc T. Goodman,Sune F. Nielsen,Andrew Berchuck,Sylvie Laboissiere,Stephanie L. Schmit,Tameka Shelford,Christopher K. Edlund,Jack A. Taylor,John K. Field,Sue K. Park,Kenneth Offit,Kenneth Offit,Kenneth Offit,Mads Thomassen,Rita K. Schmutzler,Laura Ottini,Rayjean J. Hung,Jonathan Marchini,Ali Amin Al Olama,Ulrike Peters,Rosalind A. Eeles,Michael F. Seldin,Elizabeth M. Gillanders,Daniela Seminara,Antonis C. Antoniou,Paul D.P. Pharoah,Georgia Chenevix-Trench,Stephen J. Chanock,Jacques Simard,Douglas F. Easton +99 more
TL;DR: Results from these analyses will enable researchers to identify new susceptibility loci, perform fine-mapping of new or known loci associated with either single or multiple cancers, assess the degree of overlap in cancer causation and pleiotropic effects of loci that have been identified for disease-specific risk, and jointly model genetic, environmental, and lifestyle-related exposures.
Journal ArticleDOI
Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States.
Paige Maas,Myrto Barrdahl,Amit Joshi,Paul L. Auer,Paul L. Auer,Mia M. Gaudet,Roger L. Milne,Roger L. Milne,Fredrick R. Schumacher,William F. Anderson,David P. Check,Subham Chattopadhyay,Laura Baglietto,Laura Baglietto,Christine D. Berg,Stephen J. Chanock,David G. Cox,David G. Cox,Jonine D. Figueroa,Mitchell H. Gail,Barry I. Graubard,Christopher A. Haiman,Susan E. Hankinson,Susan E. Hankinson,Robert N. Hoover,Claudine Isaacs,Laurence N. Kolonel,Loic Le Marchand,I-Min Lee,Sara Lindström,Kim Overvad,Isabelle Romieu,María José Sánchez,Melissa C. Southey,Daniel O. Stram,Rosario Tumino,Tyler J. VanderWeele,Walter C. Willett,Shumin M. Zhang,Julie E. Buring,Federico Canzian,Susan M. Gapstur,Brian E. Henderson,David J. Hunter,Graham G. Giles,Graham G. Giles,Graham G. Giles,Ross L. Prentice,Ross L. Prentice,Regina G. Ziegler,Peter Kraft,M Garcia-Closas,M Garcia-Closas,Nilanjan Chatterjee,Nilanjan Chatterjee +54 more
TL;DR: This model for absolute risk of breast cancer including SNPs can provide stratification for the population of white women in the United States and can identify subsets of the population at an elevated risk that would benefit most from risk-reduction strategies based on altering modifiable factors.
Journal ArticleDOI
A Genomewide Admixture Map for Latino Populations
Alkes L. Price,Nick Patterson,Fuli Yu,Fuli Yu,David Cox,Alicja Waliszewska,Alicja Waliszewska,Gavin J. McDonald,Gavin J. McDonald,Arti Tandon,Arti Tandon,Christine Schirmer,Christine Schirmer,Julie Neubauer,Julie Neubauer,Gabriel Bedoya,Constanza Duque,Alberto Villegas,Maria Cátira Bortolini,Francisco M. Salzano,Carla Gallo,Guido Mazzotti,Marcela K. Tello-Ruiz,Laura Riba,Carlos A. Aguilar-Salinas,Samuel Canizales-Quinteros,Marta Menjivar,William Klitz,Brian E. Henderson,Christopher A. Haiman,Cheryl A. Winkler,Teresa Tusié-Luna,Andres Ruiz-Linares,David Reich,David Reich +34 more
TL;DR: A advantage of the strategy is that the map focused on markers distinguishing Native American from other ancestries and restricted it to markers with very similar frequencies in Europeans and Africans, which decreased the number of markers needed and minimized the possibility of false disease associations.
Journal ArticleDOI
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
Zsofia Kote-Jarai,Olama Aaa.,G.G. Giles,G.G. Giles,Gianluca Severi,Gianluca Severi,Johanna Schleutker,Maren Weischer,Daniele Campa,Elio Riboli,Timothy J. Key,Henrik Grönberg,David J. Hunter,Peter Kraft,Michael J. Thun,Sue A. Ingles,Stephen J. Chanock,Stephen J. Chanock,Demetrius Albanes,Richard B. Hayes,David E. Neal,David E. Neal,Freddie C. Hamdy,Jenny L Donovan,Paul D.P. Pharoah,Fredrick R. Schumacher,Brian E. Henderson,Janet L. Stanford,Janet L. Stanford,Elaine A. Ostrander,Karina Dalsgaard Sørensen,Thilo Dörk,Gerald L. Andriole,Joanne L. Dickinson,Cezary Cybulski,Jan Lubinski,Amanda B. Spurdle,Judith A. Clements,Suzanne K. Chambers,Joanne F. Aitken,Gardiner Raf.,S. N. Thibodeau,D J Schaid,Esther M. John,Esther M. John,Christiane Maier,W. Vogel,Kathleen A. Cooney,Jong Y. Park,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hermann Brenner,Tomonori Habuchi,Zhang H-W.,Lu Y-J.,Radka Kaneva,Kenneth Muir,Sara Benlloch,Daniel Leongamornlert,Ed Saunders,Malgorzata Tymrakiewicz,N. Mahmud,Michelle Guy,Lynne T. O'Brien,R A Wilkinson,Amanda L. Hall,E J Sawyer,Tokhir Dadaev,Jonathan J. Morrison,David P. Dearnaley,David P. Dearnaley,Alan Horwich,Alan Horwich,Robert Huddart,Robert Huddart,Vincent Khoo,Vincent Khoo,Chris Parker,Chris Parker,N. van As,C.R.J. Woodhouse,A. Thompson,Timothy J. Christmas,Chris Ogden,Colin Cooper,Aritaya Lophatonanon,Melissa C. Southey,John L. Hopper,Dallas R. English,Dallas R. English,T. Wahlfors,Tammela Tlj.,Peter Klarskov,Børge G. Nordestgaard,Martin Andreas Røder,Anne Tybjærg-Hansen,Stig E. Bojesen,Ruth C. Travis,Federico Canzian,Rudolph Kaaks,Fredrik Wiklund,Markus Aly,Sara Lindström,W. R. Diver,Susan M. Gapstur,Mariana C. Stern,Roman Corral,Jarmo Virtamo,Angela Cox,Christopher A. Haiman,Loic Le Marchand,Liesel M. FitzGerald,Suzanne Kolb,Erika M. Kwon,Danielle M. Karyadi,Torben F. Ørntoft,Michael Borre,Andreas Meyer,Jürgen Serth,Meredith Yeager,Sonja I. Berndt,James R. Marthick,Briony Patterson,Dominika Wokołorczyk,Jyotsna Batra,Felicity Lose,Shannon K. McDonnell,Amit Joshi,A Shahabi,Antje E. Rinckleb,A Ray,T A Sellers,Lin H-Y.,Robert A. Stephenson,J. M. Farnham,Heiko Müller,Dietrich Rothenbacher,Norihiko Tsuchiya,Shintaro Narita,Cao G-W.,C. Slavov,Vanio Mitev,Douglas F. Easton,Rosalind A. Eeles,Rosalind A. Eeles +144 more
TL;DR: The results of stage 3 are reported, in which 1,536 SNPs are evaluated in 4,574 individuals with prostate cancer (cases) and 4,164 controls and a SNP in TERT more strongly associated with PrCa than that previously reported is identified.
Journal ArticleDOI
Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults
Mariaelisa Graff,Robert A. Scott,Anne E. Justice,Kristin L. Young,Mary F. Feitosa,Llilda Barata,Thomas W. Winkler,Audrey Y. Chu,Audrey Y. Chu,Anubha Mahajan,David Hadley,Luting Xue,Luting Xue,Tsegaselassie Workalemahu,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Marcel den Hoed,Marcel den Hoed,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Qibin Qi,Julius S. Ngwa,Frida Renström,Frida Renström,Lydia Quaye,John D. Eicher,James E. Hayes,James E. Hayes,Marilyn C. Cornelis,Marilyn C. Cornelis,Marilyn C. Cornelis,Zoltán Kutalik,Zoltán Kutalik,Elise Lim,Jian'an Luan,Jennifer E. Huffman,Jennifer E. Huffman,Weihua Zhang,Weihua Zhang,Wei Zhao,Paula J. Griffin,Toomas Haller,Shafqat Ahmad,Pedro Marques-Vidal,Stephanie A. Bien,Loic Yengo,Alexander Teumer,Albert V. Smith,Meena Kumari,Marie Neergaard Harder,Johanne Marie Justesen,Marcus E. Kleber,Marcus E. Kleber,Mette Hollensted,Kurt Lohman,Natalia V. Rivera,John Whitfield,Jing Hua Zhao,Heather M. Stringham,Leo-Pekka Lyytikäinen,Charlotte Huppertz,Charlotte Huppertz,Gonneke Willemsen,Gonneke Willemsen,Wouter J. Peyrot,Ying Wu,Kati Kristiansson,Kati Kristiansson,Ayse Demirkan,Ayse Demirkan,Myriam Fornage,Maija Hassinen,Lawrence F. Bielak,Gemma Cadby,Toshiko Tanaka,Reedik Mägi,Peter J. van der Most,Anne U. Jackson,Jennifer L. Bragg-Gresham,Veronique Vitart,Jonathan Marten,Pau Navarro,Claire Bellis,Claire Bellis,Dorota Pasko,Åsa Johansson,Soren Snitker,Yu-Ching Cheng,Joel Eriksson,Unhee Lim,Mette Aadahl,Mette Aadahl,Linda S. Adair,Najaf Amin,Beverley Balkau,Juha Auvinen,Juha Auvinen,John Beilby,John Beilby,Richard N. Bergman,Sven Bergmann,Sven Bergmann,Alain G. Bertoni,John Blangero,Amélie Bonnefond,Lori L. Bonnycastle,Judith B. Borja,Soren Brage,Fabio Busonero,Steve Buyske,Harry Campbell,Peter S. Chines,Francis S. Collins,Tanguy Corre,Tanguy Corre,George Davey Smith,Graciela E. Delgado,Nicole Dueker,Marcus Dörr,Tapani Ebeling,Tapani Ebeling,Gudny Eiriksdottir,Tõnu Esko,Jessica D. Faul,Mao Fu,Kristine Færch,Christian Gieger,Sven Gläser,Jian Gong,Penny Gordon-Larsen,Harald Grallert,Tanja B. Grammer,Niels Grarup,Gerard van Grootheest,Kennet Harald,Nicholas D. Hastie,Aki S. Havulinna,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Lynne J. Hocking,Oddgeir L. Holmens,Christina Holzapfel,Jouke-Jan Hottenga,Jie Huang,Tao Huang,Jennie Hui,Jennie Hui,Cornelia Huth,Nina Hutri-Kähönen,Alan James,Alan James,John-Olov Jansson,Min A. Jhun,Markus Juonala,Markus Juonala,Leena Kinnunen,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Ivana Kolcic,Pirjo Komulainen,Johanna Kuusisto,Kirsti Kvaløy,Mika Kähönen,Timo A. Lakka,Lenore J. Launer,Benjamin Lehne,Cecilia M. Lindgren,Cecilia M. Lindgren,Cecilia M. Lindgren,Mattias Lorentzon,Mattias Lorentzon,Robert Luben,Michel Marre,Yuri Milaneschi,Keri L. Monda,Keri L. Monda,Grant W. Montgomery,Marleen H.M. de Moor,Marleen H.M. de Moor,Antonella Mulas,Martina Müller-Nurasyid,Arthur W. Musk,Arthur W. Musk,Reija Männikkö,Satu Männistö,Narisu Narisu,Matthias Nauck,Jennifer A. Nettleton,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Sandosh Padmanabhan,Lavinia Paternoster,Jeremiah Perez,Markus Perola,Markus Perola,Markus Perola,Annette Peters,Ulrike Peters,Patricia A. Peyser,Inga Prokopenko,Hannu Puolijoki,Olli T. Raitakari,Olli T. Raitakari,Tuomo Rankinen,Laura J. Rasmussen-Torvik,Rajesh Rawal,Paul M. Ridker,Paul M. Ridker,Lynda M. Rose,Igor Rudan,Cinzia Sarti,Mark A. Sarzynski,Kai Savonen,William R. Scott,Serena Sanna,Alan R. Shuldiner,Steve Sidney,Günther Silbernagel,Blair H. Smith,Blair H. Smith,Jennifer A. Smith,Harold Snieder,Alena Stančáková,Barbara Sternfeld,Amy J. Swift,Tuija Tammelin,Sian-Tsung Tan,Barbara Thorand,Dorothée Thuillier,Liesbeth Vandenput,Henrik Vestergaard,Henrik Vestergaard,Jana V. van Vliet-Ostaptchouk,Marie-Claude Vohl,Uwe Völker,Gérard Waeber,Mark Walker,Sarah H. Wild,Andrew Wong,Alan F. Wright,M. Carola Zillikens,Niha Zubair,Christopher A. Haiman,Loic LeMarchand,Ulf Gyllensten,Claes Ohlsson,Albert Hofman,Albert Hofman,Fernando Rivadeneira,Fernando Rivadeneira,André G. Uitterlinden,Louis Pérusse,James F. Wilson,Caroline Hayward,Ozren Polasek,Francesco Cucca,Kristian Hveem,Catharina A. Hartman,Anke Tönjes,Stefania Bandinelli,Lyle J. Palmer,Sharon L.R. Kardia,Rainer Rauramaa,Thorkild I. A. Sørensen,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,Veikko Salomaa,Brenda W.J.H. Penninx,Eco J. C. de Geus,Eco J. C. de Geus,Dorret I. Boomsma,Terho Lehtimäki,Massimo Mangino,Massimo Mangino,Markku Laakso,Claude Bouchard,Nicholas G. Martin,Diana Kuh,Yongmei Liu,Allan Linneberg,Allan Linneberg,Winfried März,Winfried März,Winfried März,Konstantin Strauch,Mika Kivimäki,Tamara B. Harris,Vilmundur Gudnason,Henry Völzke,Lu Qi,Marjo-Riitta Järvelin,John C. Chambers,John C. Chambers,John C. Chambers,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Philippe Froguel,Philippe Froguel,Charles Kooperberg,Peter Vollenweider,Göran Hallmans,Torben Hansen,Oluf Pedersen,Andres Metspalu,Nicholas J. Wareham,Claudia Langenberg,David R. Weir,David J. Porteous,Eric Boerwinkle,Daniel I. Chasman,Daniel I. Chasman,Daniel I. Chasman,Gonçalo R. Abecasis,Inês Barroso,Inês Barroso,Mark I. McCarthy,Mark I. McCarthy,Timothy M. Frayling,Jeffrey R. O'Connell,Cornelia M. van Duijn,Cornelia M. van Duijn,Michael Boehnke,Iris M. Heid,Karen L. Mohlke,David P. Strachan,Caroline S. Fox,Ching-Ti Liu,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Robert J. Klein,Andrew D. Johnson,Ingrid B. Borecki,Paul W. Franks,Paul W. Franks,Paul W. Franks,Kari E. North,L. Adrienne Cupples,L. Adrienne Cupples,Ruth J. F. Loos,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen +349 more
TL;DR: In additional genome-wide meta-analyses adjusting for PA and interaction with PA, 11 novel adiposity loci are identified, suggesting that accounting for PA or other environmental factors that contribute to variation in adiposity may facilitate gene discovery.