N
Nora Pashayan
Researcher at University College London
Publications - 162
Citations - 6218
Nora Pashayan is an academic researcher from University College London. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 37, co-authored 144 publications receiving 4575 citations. Previous affiliations of Nora Pashayan include University of Melbourne & University College London Hospitals NHS Foundation Trust.
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Journal ArticleDOI
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Fredrick R. Schumacher,Ali Amin Al Olama,Sonja I. Berndt,Sara Benlloch,Mahbubl Ahmed,Edward J. Saunders,Tokhir Dadaev,Daniel Leongamornlert,Ezequiel Anokian,Clara Cieza-Borrella,Chee Goh,Mark N. Brook,Xin Sheng,Laura Fachal,Joe Dennis,Jonathan Tyrer,Kenneth Muir,Kenneth Muir,Artitaya Lophatananon,Artitaya Lophatananon,Victoria L. Stevens,Susan M. Gapstur,Brian D. Carter,Catherine M. Tangen,Phyllis J. Goodman,Ian M. Thompson,Jyotsna Batra,Jyotsna Batra,Suzanne K. Chambers,Suzanne K. Chambers,Leire Moya,Leire Moya,Judith A. Clements,Judith A. Clements,Lisa G. Horvath,Wayne D. Tilley,Gail P. Risbridger,Gail P. Risbridger,Henrik Grönberg,Markus Aly,Tobias Nordström,Paul D.P. Pharoah,Nora Pashayan,Johanna Schleutker,Teuvo L.J. Tammela,Csilla Sipeky,Anssi Auvinen,Demetrius Albanes,Stephanie J. Weinstein,Alicja Wolk,Alicja Wolk,Niclas Håkansson,Catharine M L West,Alison M. Dunning,Neil G. Burnet,Lorelei A. Mucci,Edward Giovannucci,Gerald L. Andriole,Olivier Cussenot,Geraldine Cancel-Tassin,Stella Koutros,Laura E. Beane Freeman,Karina Dalsgaard Sørensen,Torben F. Ørntoft,Michael Borre,Lovise Maehle,Eli Marie Grindedal,David E. Neal,David E. Neal,David E. Neal,Jenny L Donovan,Freddie C. Hamdy,Richard M. Martin,Ruth C. Travis,Timothy J. Key,Robert J. Hamilton,Neil E. Fleshner,Antonio Finelli,Sue A. Ingles,Mariana C. Stern,Barry S. Rosenstein,Sarah L. Kerns,Harry Ostrer,Yong-Jie Lu,Hongwei Zhang,Ninghan Feng,Xueying Mao,Xin Guo,Guomin Wang,Zan Sun,Graham G. Giles,Melissa C. Southey,Robert J. MacInnis,Robert J. MacInnis,Liesel M. FitzGerald,Liesel M. FitzGerald,Adam S. Kibel,Bettina F. Drake,Ana Vega,Antonio Gómez-Caamaño,Robert Szulkin,Martin Eklund,Manolis Kogevinas,Javier Llorca,Gemma Castaño-Vinyals,Kathryn L. Penney,Meir J. Stampfer,Jong Y. Park,Thomas A. Sellers,Hui Yi Lin,Janet L. Stanford,Janet L. Stanford,Cezary Cybulski,Dominika Wokołorczyk,Jan Lubinski,Elaine A. Ostrander,Milan S. Geybels,Børge G. Nordestgaard,Sune F. Nielsen,Maren Weischer,Rasmus Bisbjerg,Martin Andreas Røder,Peter Iversen,Hermann Brenner,Katarina Cuk,Bernd Holleczek,Christiane Maier,Manuel Luedeke,Thomas J. Schnoeller,Jeri Kim,Christopher J. Logothetis,Esther M. John,Esther M. John,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Marta Cardoso,Susan L. Neuhausen,Linda Steele,Yuan Chun Ding,Kim De Ruyck,Gert De Meerleer,Piet Ost,Azad Hassan Abdul Razack,Jasmine Lim,Soo Hwang Teo,Daniel W. Lin,Daniel W. Lin,Lisa F. Newcomb,Lisa F. Newcomb,Davor Lessel,Marija Gamulin,Tomislav Kuliš,Radka Kaneva,Nawaid Usmani,Nawaid Usmani,Sandeep Singhal,Sandeep Singhal,Chavdar Slavov,Vanio Mitev,Matthew Parliament,Matthew Parliament,Frank Claessens,Steven Joniau,Thomas Van den Broeck,Samantha E.T. Larkin,Paul A. Townsend,Claire Aukim-Hastie,Manuela Gago Dominguez,Jose Esteban Castelao,Maria Elena Martinez,Monique J. Roobol,Guido Jenster,Ron H.N. van Schaik,Florence Menegaux,Thérèse Truong,Yves Akoli Koudou,Jianfeng Xu,Kay-Tee Khaw,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hardev Pandha,Agnieszka Michael,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Sara Lindström,Constance Turman,Jing Ma,David J. Hunter,Elio Riboli,A. Siddiq,Federico Canzian,Laurence N. Kolonel,Loic Le Marchand,Robert N. Hoover,Mitchell J. Machiela,Zuxi Cui,Peter Kraft,Christopher I. Amos,David V. Conti,Douglas F. Easton,Fredrik Wiklund,Stephen J. Chanock,Brian E. Henderson,Zsofia Kote-Jarai,Christopher A. Haiman,Rosalind A. Eeles +207 more
TL;DR: A large meta-analysis combining genome-wide and custom high-density genotyping array data identifies 63 new susceptibility loci for prostate cancer, enhancing fine-mapping efforts and providing insights into the underlying biology of PrCa1.
Journal ArticleDOI
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
Rosalind A. Eeles,Ali Amin Al Olama,Sara Benlloch,Edward J. Saunders,Daniel Leongamornlert,Malgorzata Tymrakiewicz,Maya Ghoussaini,Craig Luccarini,Joe Dennis,S Jugurnauth-Little,Tokhir Dadaev,David E. Neal,David E. Neal,Freddie C. Hamdy,Jenny L Donovan,Kenneth Muir,Kenneth Muir,Graham G. Giles,Graham G. Giles,Gianluca Severi,Gianluca Severi,Fredrik Wiklund,Henrik Grönberg,Christopher A. Haiman,Fredrick R. Schumacher,Brian E. Henderson,Loic Le Marchand,Sara Lindström,Peter Kraft,David J. Hunter,Susan M. Gapstur,Stephen J. Chanock,Sonja I. Berndt,Demetrius Albanes,Gerald L. Andriole,Johanna Schleutker,Maren Weischer,Federico Canzian,Elio Riboli,Timothy J. Key,Ruth C. Travis,Daniele Campa,Sue A. Ingles,Esther M. John,Esther M. John,Richard B. Hayes,Paul D.P. Pharoah,Nora Pashayan,Kay-Tee Khaw,Janet L. Stanford,Janet L. Stanford,Elaine A. Ostrander,Lisa B. Signorello,Stephen N. Thibodeau,D J Schaid,Christiane Maier,Walther Vogel,Adam S. Kibel,Cezary Cybulski,Jan Lubinski,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hermann Brenner,Jong Y. Park,Radka Kaneva,Jyotsna Batra,Amanda B. Spurdle,Judith A. Clements,Manuel R. Teixeira,Manuel R. Teixeira,Ed Dicks,Andy C. H. Lee,Alison M. Dunning,Caroline Baynes,Don M. Conroy,Melanie Maranian,Shahana Ahmed,Koveela Govindasami,Michelle Guy,Rosemary A. Wilkinson,Emma J. Sawyer,Angela Morgan,David P. Dearnaley,Alan Horwich,Robert Huddart,Vincent Khoo,Chris Parker,Nicholas van As,C. R. J. Woodhouse,Alan Thompson,Tim Dudderidge,Chris Ogden,Colin Cooper,Artitaya Lophatananon,Angela Cox,Melissa C. Southey,John L. Hopper,Dallas R. English,Dallas R. English,Markus Aly,Jan Adolfsson,Jiangfeng Xu,Siqun L. Zheng,Meredith Yeager,Rudolf Kaaks,W. Ryan Diver,Mia M. Gaudet,Mariana C. Stern,Roman Corral,Amit Joshi,Ahva Shahabi,Tiina Wahlfors,Teuvo L.J. Tammela,Anssi Auvinen,Jarmo Virtamo,Peter Klarskov,Børge G. Nordestgaard,M. Andreas Røder,Sune F. Nielsen,Stig E. Bojesen,Stig E. Bojesen,Afshan Siddiq,Liesel M. FitzGerald,Suzanne Kolb,Erika M. Kwon,Danielle M. Karyadi,William J. Blot,Wei Zheng,Qiuyin Cai,Shannon K. McDonnell,Antje E. Rinckleb,Bettina F. Drake,Graham A. Colditz,Dominika Wokołorczyk,Robert A. Stephenson,Robert A. Stephenson,Craig C. Teerlink,Heiko Müller,Dietrich Rothenbacher,Thomas A. Sellers,Hui-Yi Lin,C. Slavov,Vanio Mitev,Felicity Lose,Srilakshmi Srinivasan,Sofia Maia,Sofia Maia,Paula Paulo,Paula Paulo,Ethan M. Lange,Kathleen A. Cooney,Antonis C. Antoniou,Daniel Vincent,Francois Bacot,Daniel C. Tessier,Zsofia Kote-Jarai,Douglas F. Easton +156 more
TL;DR: In this paper, a custom Illumina array (iCOGS) was used to genotype 211,155 SNPs in blood DNA from 25,074 prostate cancer cases and 24,272 controls from the international PRACTICAL Consortium.
Journal ArticleDOI
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
Ali Amin Al Olama,Zsofia Kote-Jarai,Sonja I. Berndt,David V. Conti,Fredrick R. Schumacher,Ying Han,Sara Benlloch,Dennis J. Hazelett,Zhaoming Wang,Ed Saunders,Daniel Leongamornlert,Sara Lindström,Sara Jugurnauth-Little,Tokhir Dadaev,Malgorzata Tymrakiewicz,Daniel O. Stram,Kristin A. Rand,Peggy Wan,Alex Stram,Xin Sheng,Loreall Pooler,Karen Park,Lucy Xia,Jonathan Tyrer,Laurence N. Kolonel,Loic Le Marchand,Robert N. Hoover,Mitchell J. Machiela,Merideth Yeager,Laurie Burdette,Charles C. Chung,Amy K. Hutchinson,Kai Yu,Chee Goh,Mahbubl Ahmed,Koveela Govindasami,Michelle Guy,Teuvo L.J. Tammela,Anssi Auvinen,Tiina Wahlfors,Johanna Schleutker,Tapio Visakorpi,Katri A. Leinonen,Jianfeng Xu,Markus Aly,Jenny L Donovan,Ruth C. Travis,Timothy J. Key,Afshan Siddiq,Federico Canzian,Kay-Tee Khaw,Atsushi Takahashi,Michiaki Kubo,Paul D.P. Pharoah,Nora Pashayan,Maren Weischer,Børge G. Nordestgaard,Sune F. Nielsen,Peter Klarskov,Martin Andreas Røder,Peter Iversen,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Janet L. Stanford,Janet L. Stanford,Suzanne Kolb,Sarah K. Holt,Beatrice S. Knudsen,Antonio Hurtado Coll,Susan M. Gapstur,W. Ryan Diver,Victoria L. Stevens,Christiane Maier,Manuel Luedeke,Kathleen Herkommer,Antje E. Rinckleb,Sara S. Strom,Curtis A. Pettaway,Edward D. Yeboah,Edward D. Yeboah,Yao Tettey,Yao Tettey,Richard B. Biritwum,Richard B. Biritwum,Andrew A. Adjei,Andrew A. Adjei,Evelyn Tay,Evelyn Tay,Ann Truelove,Shelley Niwa,Anand P. Chokkalingam,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Cezary Cybulski,Dominika Wokołorczyk,Wojciech Kluźniak,Jong Y. Park,Thomas A. Sellers,Hui-Yi Lin,William B. Isaacs,Alan W. Partin,Hermann Brenner,Aida Karina Dieffenbach,Christa Stegmaier,Constance Chen,Edward Giovannucci,Jing Ma,Meir J. Stampfer,Kathryn L. Penney,Lorelei A. Mucci,Esther M. John,Esther M. John,Sue A. Ingles,Rick A. Kittles,Adam B. Murphy,Hardev Pandha,Agnieszka Michael,Andrzej M. Kierzek,William J. Blot,Lisa B. Signorello,Wei Zheng,Demetrius Albanes,Jarmo Virtamo,Stephanie J. Weinstein,Barbara Nemesure,John D. Carpten,Cristina Leske,Suh-Yuh Wu,Anselm Hennis,Anselm Hennis,Adam S. Kibel,Benjamin A. Rybicki,Christine Neslund-Dudas,Ann W. Hsing,Ann W. Hsing,Lisa Chu,Lisa Chu,Phyllis J. Goodman,Eric A. Klein,S. Lilly Zheng,Jyotsna Batra,Judith A. Clements,Amanda B. Spurdle,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Sofia Maia,Chavdar Slavov,Radka Kaneva,Vanio Mitev,John S. Witte,Graham Casey,Elizabeth M. Gillanders,Daniella Seminara,Elio Riboli,Freddie C. Hamdy,Gerhard A. Coetzee,Qiyuan Li,Matthew L. Freedman,David J. Hunter,Kenneth Muir,Kenneth Muir,Henrik Grönberg,David E. Neal,David E. Neal,Melissa C. Southey,Graham G. Giles,Graham G. Giles,Gianluca Severi,Gianluca Severi,Michael B. Cook,Hidewaki Nakagawa,Fredrik Wiklund,Peter Kraft,Stephen J. Chanock,Brian E. Henderson,Douglas F. Easton,Rosalind A. Eeles,Christopher A. Haiman +179 more
TL;DR: These findings provide new regions for investigation into the pathogenesis of prostate cancer and demonstrate the usefulness of combining ancestrally diverse populations to discover risk loci for disease.
Journal ArticleDOI
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
David V. Conti,Burcu F. Darst,Lilit C. Moss,Edward J. Saunders,Xin Sheng,Alisha Chou,Fredrick R. Schumacher,Ali Amin Al Olama,Sara Benlloch,Tokhir Dadaev,Mark N. Brook,Ali Sahimi,Thomas J. Hoffmann,Atushi Takahashi,Koichi Matsuda,Yukihide Momozawa,Masashi Fujita,Kenneth Muir,Kenneth Muir,Artitaya Lophatananon,Peggy Wan,Loic Le Marchand,Lynne R. Wilkens,Victoria L. Stevens,Susan M. Gapstur,Brian D. Carter,Johanna Schleutker,Teuvo L.J. Tammela,Csilla Sipeky,Anssi Auvinen,Graham G. Giles,Graham G. Giles,Graham G. Giles,Melissa C. Southey,Robert J. MacInnis,Robert J. MacInnis,Cezary Cybulski,Dominika Wokołorczyk,Jan Lubinski,David E. Neal,David E. Neal,David E. Neal,Jenny L Donovan,Freddie C. Hamdy,Richard M. Martin,Børge G. Nordestgaard,Sune F. Nielsen,Maren Weischer,Stig E. Bojesen,Martin Andreas Røder,Peter Iversen,Jyotsna Batra,Suzanne K. Chambers,Leire Moya,Lisa G. Horvath,Judith A. Clements,Wayne D. Tilley,Gail P. Risbridger,Gail P. Risbridger,Henrik Grönberg,Markus Aly,Robert Szulkin,Martin Eklund,Tobias Nordström,Nora Pashayan,Alison M. Dunning,Maya Ghoussaini,Ruth C. Travis,Timothy J. Key,Elio Riboli,Jong Y. Park,Thomas A. Sellers,Hui Yi Lin,Demetrius Albanes,Stephanie J. Weinstein,Lorelei A. Mucci,Edward Giovannucci,Sara Lindström,Peter Kraft,David J. Hunter,Kathryn L. Penney,Constance Turman,Catherine M. Tangen,Phyllis J. Goodman,Ian M. Thompson,Robert J. Hamilton,Robert J. Hamilton,Neil Fleshner,Antonio Finelli,Marie-Élise Parent,Marie-Élise Parent,Janet L. Stanford,Janet L. Stanford,Elaine A. Ostrander,Milan S. Geybels,Stella Koutros,Laura E. Beane Freeman,Meir J. Stampfer,Alicja Wolk,Alicja Wolk,Niclas Håkansson,Gerald L. Andriole,Robert N. Hoover,Mitchell J. Machiela,Karina Dalsgaard Sørensen,Michael Borre,William J. Blot,Wei Zheng,Edward D. Yeboah,Edward D. Yeboah,James E. Mensah,James E. Mensah,Yong-Jie Lu,Hongwei Zhang,Ninghan Feng,Xueying Mao,Yudong Wu,Shan Chao Zhao,Zan Sun,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Catharine M L West,Neil G. Burnet,Gill Barnett,Christiane Maier,Thomas J. Schnoeller,Manuel Luedeke,Adam S. Kibel,Bettina F. Drake,Olivier Cussenot,Geraldine Cancel-Tassin,Florence Menegaux,Thérèse Truong,Yves Akoli Koudou,Esther M. John,Eli Marie Grindedal,Lovise Maehle,Kay-Tee Khaw,Sue A. Ingles,Mariana C. Stern,Ana Vega,Antonio Gómez-Caamaño,Laura Fachal,Barry S. Rosenstein,Sarah L. Kerns,Harry Ostrer,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Andreia Brandão,Stephen Watya,Alexander Lubwama,Jeannette T. Bensen,Elizabeth T. H. Fontham,James L. Mohler,James L. Mohler,Jack A. Taylor,Manolis Kogevinas,Javier Llorca,Gemma Castaño-Vinyals,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Craig C. Teerlink,Craig C. Teerlink,Chad D. Huff,Sara S. Strom,Luc Multigner,Pascal Blanchet,Laurent Brureau,Radka Kaneva,Chavdar Slavov,Vanio Mitev,Robin J. Leach,Brandi Weaver,Hermann Brenner,Katarina Cuk,Bernd Holleczek,Kai Uwe Saum,Eric A. Klein,Ann W. Hsing,Rick A. Kittles,Adam B. Murphy,Christopher J. Logothetis,Jeri Kim,Susan L. Neuhausen,Linda Steele,Yuan Chun Ding,William B. Isaacs,Barbara Nemesure,Anselm Hennis,Anselm Hennis,John D. Carpten,Hardev Pandha,Agnieszka Michael,Kim De Ruyck,Gert De Meerleer,Piet Ost,Jianfeng Xu,Azad Hassan Abdul Razack,Jasmine Lim,Soo-Hwang Teo,Lisa F. Newcomb,Daniel W. Lin,Jay H. Fowke,Christine Neslund-Dudas,Benjamin A. Rybicki,Marija Gamulin,Davor Lessel,Tomislav Kuliš,Nawaid Usmani,Nawaid Usmani,Sandeep Singhal,Matthew Parliament,Matthew Parliament,Frank Claessens,Steven Joniau,Thomas Van den Broeck,Manuela Gago-Dominguez,Manuela Gago-Dominguez,Jose Esteban Castelao,Maria Elena Martinez,Samantha E.T. Larkin,Paul A. Townsend,Paul A. Townsend,Claire Aukim-Hastie,William S. Bush,Melinda C. Aldrich,Dana C. Crawford,Shiv Srivastava,Jennifer Cullen,Gyorgy Petrovics,Graham Casey,Monique J. Roobol,Guido Jenster,Ron H.N. van Schaik,Jennifer J. Hu,Maureen Sanderson,Rohit Varma,Roberta McKean-Cowdin,Mina Torres,Nicholas Mancuso,Sonja I. Berndt,Stephen K. Van Den Eeden,Stephen K. Van Den Eeden,Douglas F. Easton,Stephen J. Chanock,Michael B. Cook,Fredrik Wiklund,Hidewaki Nakagawa,John S. Witte,Rosalind A. Eeles,Rosalind A. Eeles,Zsofia Kote-Jarai,Christopher A. Haiman +254 more
TL;DR: This paper conducted a meta-analysis of prostate cancer genome-wide association studies (107,247 cases and 127,006 controls) and identified 86 new genetic risk variants independently associated with prostate cancer risk, bringing the total to 269 known risk variants.
Journal ArticleDOI
Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer: A Life-Table Model.
TL;DR: Not offering breast cancer screening to women at lower risk could improve the cost-effectiveness of the screening program, reduce overdiagnosis, and maintain the benefits of screening.