C
Christopher A. Haiman
Researcher at University of Southern California
Publications - 783
Citations - 65352
Christopher A. Haiman is an academic researcher from University of Southern California. The author has contributed to research in topics: Breast cancer & Genome-wide association study. The author has an hindex of 106, co-authored 687 publications receiving 54813 citations. Previous affiliations of Christopher A. Haiman include University of California, San Francisco & National Institutes of Health.
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A polygenic risk score for breast cancer in U.S. Latinas and Latin-American women
Yiwey Shieh,Laura Fejerman,Paul C. Lott,Katie Marker,S Sawyer,Donglei Hu,Scott Huntsman,Javier Torres,Magdalena Echeverry,Mabel Bohorquez,Juan Carlos Martínez-Chéquer,Guadalupe Polanco-Echeverry,Ana P. Estrada-Florez,Christopher A. Haiman,Esther M. John,Lawrence H. Kushi,Gabriela Torres-Mejía,Tatianna Vidaurre,Jeffrey N. Weitzel,Sandro Casavilca Zambrano,Luis G. Carvajal-Carmona,Luis G. Carvajal-Carmona,Elad Ziv,Susan L. Neuhausen +23 more
TL;DR: The 180-SNP PRS predicts breast cancer risk in Latinas, with similar performance as reported for Europeans, and the performance of the PRS did not vary substantially according to Indigenous American ancestry.
Journal ArticleDOI
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry
Mariaelisa Graff,Anne E. Justice,Kristin L. Young,Eirini Marouli,Xinruo Zhang,Rebecca S. Fine,Elise Lim,Victoria L. Buchanan,Kristin A. Rand,Mary F. Feitosa,Mary K. Wojczynski,Lisa R. Yanek,Yaming Shao,Rebecca Rohde,Adebowale Adeyemo,Melinda C. Aldrich,Matthew A. Allison,Christine B. Ambrosone,Stefan Ambs,Christopher I. Amos,Donna K. Arnett,Larry D. Atwood,Elisa V. Bandera,Traci M. Bartz,Diane M. Becker,Sonja I. Berndt,Leslie Bernstein,Lawrence F. Bielak,William J. Blot,Erwin P. Bottinger,Donald W. Bowden,Jonathan P. Bradfield,Jennifer A. Brody,Ulrich Broeckel,Gregory L. Burke,Brian E. Cade,Qiuyin Cai,Neil E. Caporaso,Christopher S. Carlson,John D. Carpten,Graham Casey,Stephen J. Chanock,Guanjie Chen,Minhui Chen,Yii-Der Ida Chen,Wei-Min Chen,Alessandra Chesi,Charleston W. K. Chiang,Lisa Chu,Gerry A. Coetzee,David V. Conti,Richard S. Cooper,Mary Cushman,Ellen W. Demerath,Sandra L. Deming,Latchezar Dimitrov,Jingzhong Ding,W. Ryan Diver,Qing Duan,Michele K. Evans,Adeyinka G. Falusi,Jessica D. Faul,Myriam Fornage,Caroline S. Fox,Caroline S. Fox,Barry I. Freedman,Melissa Garcia,Elizabeth M. Gillanders,Phyllis J. Goodman,Omri Gottesman,Struan F.A. Grant,Xiuqing Guo,Hakon Hakonarson,Talin Haritunians,Tamara B. Harris,Curtis C. Harris,Brian E. Henderson,Anselm Hennis,Anselm Hennis,Dena G. Hernandez,Joel N. Hirschhorn,Joel N. Hirschhorn,Lorna H. McNeill,Timothy D. Howard,Barbara V. Howard,Ann W. Hsing,Ann W. Hsing,Yu Han H. Hsu,Yu Han H. Hsu,Jennifer J. Hu,Chad D. Huff,Dezheng Huo,Sue A. Ingles,Marguerite R. Irvin,Esther M. John,Karen C. Johnson,Joanne M. Jordan,Edmond K. Kabagambe,Sun J. Kang,Sharon L.R. Kardia,Brendan J. Keating,Rick A. Kittles,Eric A. Klein,Suzanne Kolb,Laurence N. Kolonel,Charles Kooperberg,Lewis H. Kuller,Abdullah Kutlar,Leslie A. Lange,Carl D. Langefeld,Loic Le Marchand,Hampton L. Leonard,Guillaume Lettre,Albert M. Levin,Yun Li,Jin Li,Yongmei Liu,Youfang Liu,Simin Liu,Kurt Lohman,Vaneet Lotay,Yingchang Lu,Yingchang Lu,William Maixner,JoAnn E. Manson,Barbara McKnight,Yan Meng,Keri L. Monda,Keri L. Monda,Kris Monroe,Jason H. Moore,Thomas H. Mosley,Poorva Mudgal,Adam B. Murphy,Rajiv Nadukuru,Mike A. Nalls,Katherine L. Nathanson,Uma Nayak,Amidou N'Diaye,Barbara Nemesure,Christine Neslund-Dudas,Marian L. Neuhouser,Sarah J. Nyante,Heather M. Ochs-Balcom,Temidayo O. Ogundiran,Adesola Ogunniyi,Oladosu Ojengbede,Hayrettin Okut,Olufunmilayo I. Olopade,Andrew F. Olshan,Badri Padhukasahasram,Julie R. Palmer,Cameron D. Palmer,Cameron D. Palmer,Nicholette D. Palmer,George J. Papanicolaou,Sanjay R. Patel,Curtis A. Pettaway,Patricia A. Peyser,Michael F. Press,D. C. Rao,Laura J. Rasmussen-Torvik,Susan Redline,Alexander P. Reiner,Suhn K. Rhie,Jorge L. Rodriguez-Gil,Charles N. Rotimi,Jerome I. Rotter,Edward A. Ruiz-Narváez,Benjamin A. Rybicki,Babatunde L. Salako,Michèle M. Sale,Maureen Sanderson,Eric E. Schadt,Pamela J. Schreiner,Claudia Schurmann,Ann G. Schwartz,Daniel Shriner,Lisa B. Signorello,Andrew B. Singleton,David S. Siscovick,Jennifer A. Smith,Shad B. Smith,Elizabeth K. Speliotes,Margaret R. Spitz,Janet L. Stanford,Janet L. Stanford,Victoria L. Stevens,Alex Stram,Sara S. Strom,Lara Sucheston,Yan V. Sun,Salman M. Tajuddin,Herman A. Taylor,Kira C. Taylor,Bamidele O. Tayo,Michael J. Thun,Margaret A. Tucker,Dhananjay Vaidya,David Van Den Berg,Sailaja Vedantam,Sailaja Vedantam,Mara Z. Vitolins,Zhaoming Wang,Erin B. Ware,Sylvia Wassertheil-Smoller,David R. Weir,John K. Wiencke,Scott M. Williams,L. Keoki Williams,James G. Wilson,John S. Witte,Margaret Wrensch,Xifeng Wu,Jie Yao,Neil A. Zakai,Krista A. Zanetti,Babette S. Zemel,Wei Zhao,Jing Hua Zhao,Wei Zheng,Degui Zhi,Jie Zhou,Xiaofeng Zhu,Regina G. Ziegler,J. M. Zmuda,Alan B. Zonderman,Bruce M. Psaty,Ingrid B. Borecki,Ingrid B. Borecki,L. Adrienne Cupples,L. Adrienne Cupples,Ching-Ti Liu,Christopher A. Haiman,Ruth J. F. Loos,Maggie C.Y. Ng,Kari E. North +236 more
TL;DR: In this article, a trans-ethnic meta-analysis revealed novel signals and further improved fine-mapping of putative causal variants in loci shared between African and European ancestry populations.
Journal ArticleDOI
IGF1, IGFBP1 and IGFBP3 genes and mammographic density: The Multiethnic Cohort
Martijn Verheus,Gertraud Maskarinec,Christy G. Woolcott,Christopher A. Haiman,Loic Le Marchand,Brian E. Henderson,Iona Cheng,Laurence N. Kolonel +7 more
TL;DR: There is weak evidence that genetic variations in IGFBP1 or IGFBP3 may be related to mammographic density, and ethnicity may modify these relations.
Journal ArticleDOI
No Association of Type 2 Diabetes Risk Variants and Prostate Cancer Risk: the Multiethnic Cohort and PAGE
Kevin M. Waters,Lynne R. Wilkens,Kristine R. Monroe,Daniel O. Stram,Laurence N. Kolonel,Brian E. Henderson,Loic Le Marchand,Christopher A. Haiman +7 more
TL;DR: Resequencing and fine-mapping of the loci for diabetes and prostate cancer that were identified by genome-wide association studies are necessary to understand any genetic contribution for the inverse association between these common diseases.
Journal ArticleDOI
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Jonathan Tyrer,Daniel R. Barnes,Katja K.H. Aben,Muriel A. Adank,Simona Agata,Hoda Anton-Culver,Gerassimos Aravantinos,Banu Arun,Annelie Augustinsson,Elisa V. Bandera,Rosa B. Barkardottir,Javier Benitez,Marina Bermisheva,Marcus Q. Bernardini,Line Bjørge,Amanda Black,Natalia Bogdanova,James D. Brenton,R. Butzow,Ian G. Campbell,Jenny Chang-Claude,Kexin Chen,Yoke-Eng Chiew,Kathleen Claes,Fabienne Noura Lesueur Mebirouk,Fabienne Lesueur,Noura Mebirouk,Christoph Rita K. Engel Schmutzler,Daniel Eleanor Diana M. D. Gareth Barrowdale Davies Eccles Evans,Daniel Barrowdale,Eleanor Davies,D. Gareth Evans,Fergus J. Couch,Robin de Putter,Peter Devilee,Yuan Chun Ding,Jennifer A. Doherty,Susan M. Domchek,Thilo Dörk,Diana Eccles,Heather Eliassen,Christoph Engel,Gareth Evans,Peter A. Fasching,James M. Flanagan,Renée T. Fortner,Eva Machackova,Eitan Friedman,Patricia A. Ganz,Francesca Gensini,Marc T. Goodman,Jacek Gronwald,Eric Hahnen,Holly R. Harris,Mikael Hartman,Michelle A.T. Hildebrandt,Estrid Høgdall,John L. Hopper,David G. Huntsman,Georgia Chenevix-Trench,Muriel A. Peter Annemieke H. Adank Devilee van der Hout,Annemieke H. van der Hout,Ramunas Janavicius,Allan Jensen,Esther M. John,Daehee Kang,Beth Y. Karlan,Linda E. Kelemen,E. Khusnutdinova,Byoung-Gie Kim,Ian K. Komenaka,Jolanta Kupryjanczyk,Allison W. Kurian,Diether Lambrechts,Melissa C. Larson,Conxi Lázaro,Nhu D. Le,Goska Leslie,Lian Li,Jennifer T. Loud,Phuong L. Mai,Siranoush Manoukian,Lesley McGuffog,Iain A. McNeish,Usha B Menon,Austin Miller,Francesmary Modugno,Kirsten B. Moysich,Elizabeth G. Munro,Katherine L. Nathanson,Susan L. Neuhausen,Heli Nevanlinna,Finn Cilius Nielsen,Liene Nikitina-Zake,Kunle Odunsi,Kenneth Offit,Edith Olah,Siel Olbrecht,Håkan Olsson,Michael T. Parsons,Harshad Pathak,Inge Søkilde Pedersen,Ana Peixoto,Tanja Pejovic,Beth N. Peshkin,Darya Prokofyeva,Paolo Radice,Johanna Rantala,Harvey A. Risch,Eric A. Ross,Ingo B. Runnebaum,Penny Soucy,Rita K. Schmutzler,Weiva Sieh,Jacques Simard,Melissa C. Southey,Helen Steed,Dominique Stoppa-Lyonnet,Yen Y. Tan,Manuel R. Teixeira,Kathryn L. Terry,Mary Beth Terry,Eileen Dareng,Michelle R. Jones,Natalia Antonenkova,Matthias W. Beckmann,Alicia Beeghly-Fadiel,Line Bjørge,Agnieszka Budzilowska,Hui Cai,Rikki Cannioto,Stephen J. Chanock,Ken Chen,Linda S. Cook,Fanny Dao,Joe Dennis,Andreas du Bois,M. Dürst,Graham G. Giles,Christopher A. Haiman,Niclas Håkansson,Florian Heitz,Claus Høgdall,Ruea-Yea Huang,Chad D. Huff,Anna Jakubowska,Michael Jones,Anthony N. Karnezis,Lambertus A. Kiemeney,Susanne K. Kjaer,Jenny Lester,Douglas A. Levine,Karen H. Lu,Jan Lubinski,Jeffrey R. Marks,Rayna K. Matsuno,Keitaro Matsuo,Taymaa May,John R. McLaughlin,Roger L. Milne,Albina N. Minlikeeva,Sara H. Olson,Ana Osorio,Sue K. Park,Jennifer B. Permuth,Anna M. Piskorz,Marjorie J. Riggan,Cristina Rodríguez-Antona,Mary Anne Rossing,Dale P. Sandler,Veronica Wendy Setiawan,Kang Shan,Honglin Song,Rebecca Sutphen,Anthony J. Swerdlow,Soo Hwang Teo,Pamela J. Thompson,Liv Cecilie Vestrheim Thomsen,Linda J. Titus,Ruth C. Travis,Elena Valen,Frances Wang,Nicolas Wentzensen,Alice S. Whittemore,Alicja Wolk,Anna H. Wu,Drakoulis Yannoukakos,Argyrios Ziogas,Susan J. Ramus,Celeste Leigh Pearce,Alvaro N.A. Monteiro,Ellen L. Goode,Joellen M. Schildkraut,Simon A. Gayther,Xin Yang,Irene L. Andrulis,Judith Balmaña,Bernardo Bonanni,Åke Borg,Saundra S. Buys,Maria A. Caligo,Hayley Cassingham,Wendy K. Chung,Sarah Colonna,Mary B. Daly,M. De La Hoya,Allison DePersia,Orland Diez,Judy Garber,Gord Glendon,Andrew K. Godwin,Mark I. Greene,Ute Hamann,Thomas van Overeem Hansen,Peter J. Hulick,Evgeny N. Imyanitov,Claudine Isaacs,Paul A. James,Oskar T. Johannsson,Ava Kwong,Jingmei Li,Marco Montagna,Joanne Ngeow Yuen Yie,Henriette Roed Nielsen,Olufunmilayo I. Olopade,Laura Papi,Harshal Pathak,Pedro Pérez-Segura,Paolo Peterlongo,Eric E. Ross,Marta Santamariña,Christian F. Singer,Anna P. Sokolenko,Nadine Tung,Elizabeth J. van Rensburg,Ana Vega,Barbara Wappenschmidt,Katia Zavaglia,Mads Thomassen,Darcy L. Thull,Marc Tischkowitz,Amanda E. Toland,Diana Torres,Britton Trabert,Shelley S. Tworoger,Anne M. van Altena,Els Van Nieuwenhuysen,Digna R. Velez Edwards,Robert A. Vierkant,Penelope M. Webb,Clarice R. Weinberg,Jeffrey N. Weitzel,Emily White,Stacey J. Winham,Yin Ling Woo,Li Yan,Wei Zheng,Kristin K. Zorn,Zdenek Kleibl,Douglas F. Easton,Kate Lawrenson,Antoinette DeFazio,Thomas A. Sellers,Julie M. Cunningham,Andrew Berchuck,Antonis C. Antoniou,Paul D.P. Pharoah +266 more
TL;DR: In this article , the authors implemented computationally efficient, penalized, logistic regression models (lasso, elastic net, stepwise) to individual level genotype data and a Bayesian framework with continuous shrinkage, "select and shrink for summary statistics" (S4), to summary level data for epithelial non-mucinous ovarian cancer risk prediction.