C
Christopher A. Walsh
Researcher at Howard Hughes Medical Institute
Publications - 470
Citations - 62520
Christopher A. Walsh is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Cerebral cortex & Microcephaly. The author has an hindex of 123, co-authored 455 publications receiving 55874 citations. Previous affiliations of Christopher A. Walsh include University of Liverpool & Newcastle University.
Papers
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Journal ArticleDOI
The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets
Ayako Y. Murayama,Ken-ichiro Kuwako,Ken-ichiro Kuwako,Junko Okahara,Byoung-Il Bae,Byoung-Il Bae,Masako Okuno,Hiromi Mashiko,Tomomi Shimogori,Christopher A. Walsh,Christopher A. Walsh,Erika Sasaki,Hideyuki Okano +12 more
TL;DR: A possible pathogenic role for GABAergic neuron in the cerebral cortex of patients with GPR56 mutations is indicated by a transgenic marmoset line in which EGFP is expressed under the control of the human minimal e1m promoter.
Journal ArticleDOI
A neural stem cell paradigm of pediatric hydrocephalus.
Phan Q. Duy,Pasko Rakic,Seth L. Alper,Stephanie M. Robert,Adam J. Kundishora,William E. Butler,Christopher A. Walsh,Nenad Sestan,Daniel H. Geschwind,Sheng Chih Jin,Kristopher T. Kahle +10 more
TL;DR: It is proposed that heterogenous defects in the development of NSCs are neuroprogenitor cells that comprise the germinal neuroepithelium lining the prenatal brain ventricles, leading to abnormal brain-CSF biomechanical interactions that facilitate passive pooling of CSF and secondary ventricular distention.
Patent
Embryonic cerebrospinal fluis (e-csf), proteins from e-csf, and related methods and compositions
TL;DR: In this article, a proteomic analysis of embryonic cerebrospinal fluid (e-CSF) in human and rats was performed, and methods and compositions for cell culture including components of eCSF or fragments thereof.
Journal ArticleDOI
Mapping of the mouse hyh gene to a YAC/BAC contig on proximal Chromosome 7
TL;DR: A physical map and transcript map may be useful for positional cloning of genes in this unusually gene-rich region of the genome and a number of potential candidate genes within this interval have been identified.
Journal ArticleDOI
Genetic malformations of the human frontal lobe
Dina Amrom,Christopher A. Walsh +1 more
TL;DR: Interest in genetic malformations of the frontal lobe has grown from the recognition that certain brain mal Formations have a predilection for the frontal lobes or are more severe in the anterior brain.